oxytetracycline--anhydrous and Toxoplasmosis--Animal

Toxoplasma gondii tachyzoites were seen in the placenta of a late-term aborted Greenland muskox (Ovibos moschatus wardi) fetus in a captive herd at the San Francisco Zoo. The organism stained with anti-T. gondii polyclonal rabbit serum but not with anti-Neospora caninum serum. The dam had a Toxoplasma titer of > or =1:3,200 at the time of abortion and in each of the previous 3 yr (modified agglutination test). The muskox is a new host record for T. gondii.

Topics: Abortion, Veterinary; Agglutination Tests; Animals; Anti-Infective Agents, Local; Antibodies, Protozoan; Birth Weight; Female; Histocytochemistry; Oxytetracycline; Placenta; Povidone-Iodine; Pregnancy; Ruminants; Tetracyclines; Toxoplasma; Toxoplasmosis, Animal

During 1978-79 there was an outbreak of abortion in a large sheep flock during which approximately 10 per cent of the breeding ewes aborted. Both Toxoplasma gondii and Chlamydia ovis (the agent of enzootic abortion of ewes) were considered to be involved. In the year following this outbreak (1979-80), 156 ewes (11.4 per cent) aborted and the majority of cases were diagnosed as enzootic abortion: only one case showed gross pathology typical of toxoplasmosis. Serology carried out on sera collected from ewes at the time of abortion and at two post abortion samplings demonstrated that large numbers of animals had high titres against enzootic abortion of ewes while the prevalence of sheep with titres against toxoplasmosis was relatively low. Following the introduction of control measures to reduce the spread of enzootic abortion of ewes, the abortion rate in 1980-81 fell to 2.2 per cent. A small-scale trial was carried out to investigate the prophylactic effect of long acting oxytetracycline against enzootic abortion of ewes when given to pregnant sheep three weeks before lambing. Results indicated that treatment reduced the number of abortions in comparison with untreated controls.

Topics: Abortion, Veterinary; Animals; Chlamydia Infections; Disease Outbreaks; Female; Oxytetracycline; Pregnancy; Scotland; Sheep; Sheep Diseases; Toxoplasmosis, Animal

Topics: Anilides; Animals; Anti-Bacterial Agents; Colistin; Mice; Oxytetracycline; Penicillin V; Pyrimethamine; Research; Rifamycins; Spiramycin; Sulfadiazine; Tetracyclines; Toxoplasmosis; Toxoplasmosis, Animal; Toxoplasmosis, Ocular

Topics: Animals; Mice; Oxytetracycline; Toxoplasmosis; Toxoplasmosis, Animal