oxytetracycline--anhydrous and Streptococcal-Infections

Topics: Acute Radiation Syndrome; Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Diphtheria; Enterobacter aerogenes; Escherichia coli Infections; Oxytetracycline; Penicillin G; Penicillins; Pharmacology; Proteus Infections; Pseudomonas Infections; Radiation Injuries, Experimental; Rats; Research; Staphylococcal Infections; Streptococcal Infections; Streptomycin

To determine whether antibiotic and supportive treatment would improve outcome for dairy cows with naturally developing clinical mastitis, compared with supportive treatment alone.. Randomized controlled trial.. 124 cows in one herd with 172 episodes of clinical mastitis.. Cows were examined at the onset of clinical mastitis, assigned a severity score, and randomly assigned to receive antibiotic (intramammary administration of cephapirin, i.v. administration of oxytetracycline, or both) and supportive treatment (administration of oxytocin, stripping of affected glands, and, in severely affected cows, administration of flunixin meglumine or fluids) or supportive treatment alone. Treatment was continued until 24 hours after signs of clinical mastitis resolved (clinical cure). Milk samples from affected glands were submitted for bacterial culture before initial treatment and every 2 weeks thereafter until the causative organism was no longer isolated (bacteriologic cure).. When mastitis was caused by Streptococcus spp or coliform bacteria, clinical cure rate by the tenth milking was significantly higher if antibiotics were used. Bacteriologic cure rate at 14 days was significantly higher when antibiotics were used, particularly if mastitis was caused by Streptococcus spp. Cows receiving antibiotics developed fewer subsequent episodes of clinical mastitis during the 60 days after the initial episode of mastitis and had less severe clinical disease than cows that did not.. Results suggest that, in herds in which mastitis is often caused by environmental bacteria, antibiotic and supportive treatment may result in a better outcome for cows with clinical mastitis than supportive treatment alone.

Topics: Animals; Anti-Bacterial Agents; Cattle; Cephalosporins; Cephapirin; Combined Modality Therapy; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Mastitis, Bovine; Microbial Sensitivity Tests; Oxytetracycline; Recurrence; Severity of Illness Index; Streptococcal Infections; Treatment Outcome

This study carried out at the Saint-Germain-en-Laye Hospital maternity ward included all the neonates delivered between February and September 1989 who exhibited no abnormal manifestations during their stay in the ward, except for ocular symptoms in some subjects. Nine hundred neonates were enrolled. Each day, one of two eyedrop preparations for the prevention of neonatal ocular infections was selected at random. Investigators were blinded to the preparation used. Study subjects were evaluated twice, between D1 and D7 (900 infants) and between D15 and D30 (407 infants). Ocular findings were classified as follows: normal, minimally abnormal (isolated swelling of the eyelids, clear discharge), or frankly abnormal (conjunctivitis, purulent discharge). A bacteriologic study was performed in all patients with minimally abnormal or abnormal findings. Between D1 and D7, ocular symptoms were significantly (p less than 0.05) more prevalent in neonates treated with silver nitrate than in neonates treated with oxytetracycline hydrochloride. This difference was no longer present between D15 and D30. Bacteriologic studies recovered no gonococci. One enfant in the oxytetracycline group had bacteriologically confirmed Chlamydia trachomatis ocular infection. The other organisms recovered were mainly Staphylococcus aureus and non-hemolytic streptococci. In inclusion, no currently available eyedrop preparation offers complete protection against C. trachomatis but tolerance is considerably better with oxytetracycline hydrochlorate than with silver nitrate.

Topics: Conjunctivitis, Bacterial; Female; Humans; Infant, Newborn; Male; Ophthalmic Solutions; Oxytetracycline; Silver Nitrate; Staphylococcal Infections; Streptococcal Infections; Time Factors

Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dermatomycoses; Drug Tolerance; Enterobacteriaceae Infections; Erythema; Female; Humans; Male; Middle Aged; Ointments; Oxytetracycline; Placebos; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections; Time Factors

Topics: Adolescent; Adult; Bacterial Infections; Clinical Trials as Topic; Diabetes Complications; Doxycycline; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Oxytetracycline; Skin Diseases, Infectious; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus pyogenes; Thoracic Diseases; Time Factors

Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Drug Hypersensitivity; Female; Humans; Injections, Intravenous; Male; Middle Aged; Oxytetracycline; Peritonitis; Staphylococcal Infections; Streptococcal Infections; Surgical Wound Infection

The objectives of this study were to determine the prevalence of S. equi in a horse population in Colombia, to determine the risk factors associated with its detection in the guttural pouches and to report the antimicrobial susceptibility of the isolates. Fifteen farms and 137 horses >6 months of age were enrolled. Sampling was randomly, stratified and proportional to the population size of each farm. The guttural pouch (GP) was swabbed via endoscopic guidance and culture was performed. DNA extraction and conventional PCR were performed in colonies compatibles with S. equi, the PCR products were sequenced and subjected to BLAST analysis. Antimicrobial drug sensitivity was assessed using an antimicrobial disc diffusion assay including penicillin, ceftiofur, trimethoprim-sulfamethoxasole (TMS), enrofloxacin and oxytetracycline. A mixed logistic regression model was constructed to evaluate risk factors associated with the presence of S. equi. The S. equi culture prevalence in the GP was 15%; 13.5 % for S. equi subsp. equi and 1.5% for S. equi subsp. zooepidemicus. History of travel was associated with the presence of S. equi, whereas every 1-year increase in age decreased the risk for S. equi detection in the GP. All isolates were susceptible to TMS, ceftiofur and penicillin, but resistant to enrofloxacin and oxytetracycline. S. equi is present in horses in Colombia, with a high prevalence and appear to be endemic in the tested population. Younger horses and horses with recent history of travelling had higher odds of testing positive for S. equi in swabs of the GP.

Topics: Animals; Colombia; Enrofloxacin; Horse Diseases; Horses; Oxytetracycline; Penicillins; Prevalence; Risk Factors; Streptococcal Infections; Streptococcus equi

Topics: Animals; Anti-Bacterial Agents; Brazil; Carrier State; Cichlids; Fish Diseases; Microbial Sensitivity Tests; Oxytetracycline; Streptococcal Infections; Streptococcus agalactiae

Lancefield group C Streptococcus dysgalactiae is an emerging fish pathogen, which was first isolated in 2002 in Japan. Streptococcus dysgalactiae isolates collected from diseased fish in Japan (n=12), Taiwan (n=12), China (n=2), Malaysia (n=3), and Indonesia (n=1) were characterized using biased sinusoidal field gel electrophoresis (BSFGE), sodA gene sequence analysis, and antimicrobial susceptibility. These isolates exhibited high phenotypic homogeneity irrespective of the countries from where the strains were collected. Seventeen isolates were found to be resistant to oxytetracycline and carried the tet(M) gene, except for the strains collected in Taiwan and the PP1564 strain collected in China. The sodA gene sequence analysis revealed that 23 isolates were identical, except for one Japanese isolate (KNH07902), in which a single nucleotide differed from that of the other isolates. Based on BSFGE typing by ApaI macrorestriction, the isolates - including the Japanese, Taiwanese, and Chinese isolates - could be grouped into one main cluster at a 70% similarity level. However, the macrorestriction genotypes of some isolates were apparently distinct from those of the main cluster.

Topics: Animals; Anti-Bacterial Agents; Asia, Eastern; Asia, Southeastern; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Fish Diseases; Genetic Variation; Genome, Bacterial; Oxytetracycline; Perciformes; Phylogeny; Sequence Analysis, DNA; Smegmamorpha; Streptococcal Infections; Streptococcus; Superoxide Dismutase

Topics: Abscess; Adult; Chronic Disease; Drug Combinations; Drug Therapy, Combination; Erythromycin; Female; Folliculitis; Furunculosis; Humans; Male; Middle Aged; Oxytetracycline; Pyoderma; Skin Ulcer; Staphylococcal Infections; Streptococcal Infections

Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Child; Child, Preschool; Conjunctivitis; Female; Humans; Klebsiella Infections; Male; Microbial Sensitivity Tests; Middle Aged; Ointments; Oxytetracycline; Staphylococcal Infections; Streptococcal Infections

Topics: Ampicillin; Anti-Bacterial Agents; Floxacillin; Gentamicins; Haemophilus Infections; Haemophilus influenzae; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mycoplasma Infections; Oxytetracycline; Penicillin G; Penicillin Resistance; Pneumonia; Streptococcal Infections

Topics: Aerosols; Candidiasis, Cutaneous; Escherichia coli Infections; Humans; Oxytetracycline; Polymyxins; Powders; Proteus Infections; Pseudomonas Infections; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections

Germs in patients suffering from nonspecific odontogenous infections described in a previous paper were analysed with regard to their resistance to chemotherapy (1964 to 1971). At the same time it was discovered that in the bacteria groups: staphyloccocus aureus, streptococci and pneumococci and enterobacteriaceae plus pseudomonas (344 strains) their sensitivity to penicillin, streptomycin, chloramphenicol, oxytetracyclin, erythromycin, polymyxin B and nifurantin varied in several and significant ways. Significant changes were established in the resistance of staphylococcus aureus to all the potentially effective antibiotics, while from 1969 to 1971 the strains with the least resistance appeared. In the 1970 to 1971 period strepto- and pneumococci showed insensitivity to penicillin and streptomycin more frequently than before. From 1969 to 1971 entero-bacteriaceae and pseudomonas also showed evidence of increasing loss of sensitivity to chloramphenicol and oxytetracyclin, whereas the frequency of strains resistant to polymyxin B and nifurantine diminished. The findings are being discussed.

Topics: Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Enterobacteriaceae Infections; Erythromycin; Focal Infection, Dental; Humans; Microbial Sensitivity Tests; Nitrofurantoin; Oxytetracycline; Penicillin Resistance; Penicillins; Pneumococcal Infections; Polymyxins; Pseudomonas Infections; Staphylococcal Infections; Streptococcal Infections; Streptomycin

Some 115 R- and 143 S-streptococcal strains were isolated from 258 pigs that had died or been killed for disease, between 1969 and 1973. They were cultured and biochemically tested for sensitivity to chemotherapeutics. All R- and S-strains were of normal sensitivity to penicillin and, with few exceptions, to chloramphenicol and oxytetracycline as well. Most of the strains caused primary Sc.-infection, such as septicaemia, leptomeningitis, endocarditis, and arthritis. R-Sc.-infections were contracted mainly by store pigs and animals in advenced age, while S-Sc.-infections affected mainly piglets.

Topics: Animals; Arthritis; Chloramphenicol; Endocarditis; Meningitis; Oxytetracycline; Penicillins; Sepsis; Streptococcal Infections; Streptococcus; Swine; Swine Diseases

Topics: Ampicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Bronchopneumonia; Chloramphenicol; Corneal Ulcer; Diarrhea; Enteritis; Female; Horse Diseases; Horses; Male; Oxytetracycline; Penicillin Resistance; Penicillins; Pleurisy; Pneumonia; Pneumonia, Aspiration; Pneumonia, Pneumocystis; Postoperative Complications; Salmonella Infections, Animal; Sepsis; Streptococcal Infections; Uterine Diseases

Topics: Diagnosis, Differential; Humans; Male; Middle Aged; Oxytetracycline; Staphylococcal Infections; Streptococcal Infections; Tooth, Impacted

Topics: Administration, Oral; Adult; Aged; Bacterial Infections; Doxycycline; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; In Vitro Techniques; Klebsiella Infections; Male; Methacycline; Microbial Sensitivity Tests; Middle Aged; Oxytetracycline; Respiratory Tract Infections; Staphylococcal Infections; Streptococcal Infections; Tetracycline; Urinary Tract Infections

Topics: Abscess; Administration, Oral; Animal Feed; Animals; Anti-Bacterial Agents; Bacterial Vaccines; Chlortetracycline; Germ-Free Life; Lymphadenitis; Oxytetracycline; Penicillin G Benzathine; Streptococcal Infections; Streptococcus; Swine; Swine Diseases; Vaccination

Topics: Aged; Biguanides; Drug Resistance, Microbial; Female; Humans; Leg Ulcer; Male; Microbial Sensitivity Tests; Middle Aged; Oxytetracycline; Polymyxins; Powders; Serratia marcescens; Streptococcal Infections; Streptococcus; Time Factors

Topics: Cellulitis; Cephaloridine; Drainage; Female; Gases; Humans; Kanamycin; Male; Mediastinitis; Middle Aged; Neck; Oxytetracycline; Peritonsillar Abscess; Radiography; Streptococcal Infections; Sulfadimethoxine; Tracheotomy

Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Clostridium Infections; Debridement; Guinea Pigs; Kanamycin; Military Medicine; Oxytetracycline; Penicillins; Pseudomonas Infections; Soil Microbiology; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Wound Infection

Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Blood; Child; Child, Preschool; Ear, Middle; Female; Haemophilus influenzae; Humans; Injections, Intramuscular; Male; Middle Aged; Otitis Media; Oxytetracycline; Penicillin G; Pneumococcal Infections; Streptococcal Infections

Topics: Humans; Oxytetracycline; Penicillin G; Penicillinase; Pharyngitis; Staphylococcus; Streptococcal Infections

Topics: Abortion, Septic; Anti-Bacterial Agents; Bile Ducts; Chloramphenicol; Emetine; Escherichia coli Infections; Female; Humans; Kanamycin; Neomycin; Oxytetracycline; Paraplegia; Penicillins; Peritonitis; Pregnancy; Pressure Ulcer; Pseudomonas Infections; Pyelonephritis; Pyoderma; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline

Topics: Abscess; Diathermy; Drug Therapy; Eyelids; Gangrene; Humans; Oxytetracycline; Penicillins; Postoperative Complications; Postoperative Period; Staphylococcal Infections; Streptococcal Infections; Sulfonamides; Surgical Wound Infection

Topics: Blood Coagulation Tests; Child; Clinical Laboratory Techniques; Fibrinolysin; Gangrene; Hemostasis; Heparin; Humans; Leg; Lower Extremity; Oxytetracycline; Penicillins; Streptococcal Infections; Sympathectomy

Topics: Administration, Topical; Adrenocorticotropic Hormone; Cortisone; Dermatitis; Dermatitis, Contact; Dermatitis, Exfoliative; Fluocinolone Acetonide; Fluorometholone; Hand Dermatoses; Humans; Hydrocortisone; Lichen Planus; Neurodermatitis; Oxytetracycline; Pemphigus; Prednisolone; Progesterone; Proteus Infections; Skin Diseases; Staphylococcal Infections; Streptococcal Infections; Tinea

Topics: Abscess; Arthritis; Child; Chloramphenicol; Diagnosis, Differential; Drainage; Erythromycin; Humans; Infant; Joint Diseases; Novobiocin; Osteomyelitis; Oxytetracycline; Penicillins; Sepsis; Staphylococcal Infections; Streptococcal Infections; Suppuration; Surgical Procedures, Operative; Tetracycline

Topics: Alcaligenes; Alcohols; Anti-Infective Agents; Chloramphenicol; Classification; Enterococcus faecalis; Escherichia coli Infections; Fermentation; Humans; Inositol; Nitrofurantoin; Oxytetracycline; Pseudomonas Infections; Streptococcal Infections; Streptomycin; Sucrose; Sulfathiazoles; Urinary Tract Infections; Urine

Topics: Child; Chlortetracycline; Diethylstilbestrol; Erythromycin; Escherichia coli Infections; Female; Gentian Violet; Humans; Ointments; Oxytetracycline; Penicillins; Piperazines; Staphylococcal Infections; Streptococcal Infections; Trichomonas Vaginitis; Vulvovaginitis

Forty cases of gonococcal urethritis were treated with oxytetracycline using various dosage schedules; there were 37 cures and three failures. The most convenient and most effective dosage was found to be 250 mg. oxytetracycline, given as a single intramuscular injection of 5 c.c.A series of 40 patients with non-gono-coccal urethritis was also collected. Two cases of urethritis due to Trichomonas vaginalis and two due to Candida albicans were removed from the series. Of the 36 cases which remained, cure was obtained with the use of oxytetracycline in different dosages in 30 cases; six cases were failures. The dosage which gave the best result in the therapy of non-gonococcal urethritis was 250 mg. oxytetracycline (5 c.c.), given as a single intramuscular injection, plus 250 mg. orally, four times a day for four days.The effectiveness of oxytetracycline in the treatment of urethritis has not decreased.

Topics: Candidiasis; Gonorrhea; Humans; Male; Oxytetracycline; Proteus Infections; Pseudomonas Infections; Staphylococcal Infections; Streptococcal Infections; Trichomonas Infections; Trichomonas vaginalis; Urethritis

Topics: Anti-Bacterial Agents; Chlortetracycline; Dogs; Enterobacter aerogenes; Escherichia coli Infections; Kanamycin; Neomycin; Oxytetracycline; Parotid Neoplasms; Penicillins; Peritonitis; Pharmacology; Proteus Infections; Rabbits; Rats; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Sulfonamides

Topics: Burns; Candidiasis; Chloramphenicol; Chlortetracycline; Escherichia coli Infections; Humans; Influenza, Human; Klebsiella; Oximetry; Oxygen Inhalation Therapy; Oxytetracycline; Penicillins; Pneumococcal Infections; Pneumonia; Proteus Infections; Pseudomonas Infections; Staphylococcal Infections; Statistics as Topic; Streptococcal Infections; Streptomycin; Sulfanilamide; Sulfanilamides

Topics: Animals; Chlortetracycline; Cortisone; Immunization; Mice; Oxytetracycline; Streptococcal Infections; Vaccination

Topics: Animals; Anti-Bacterial Agents; Chlortetracycline; Mice; Oxytetracycline; Penicillins; Streptococcal Infections; Streptomycin

Topics: Chlortetracycline; Humans; Oxytetracycline; Penicillins; Pharyngitis; Scarlet Fever; Streptococcal Infections; Tonsillitis

Topics: Bacteriology; Humans; Meningitis; Oxytetracycline; Penicillins; Streptococcal Infections; Streptococcus pyogenes; Sulfadiazine

Topics: Burns; Chlortetracycline; Oxytetracycline; Penicillins; Streptococcal Infections; Streptococcus pyogenes