oxytetracycline--anhydrous and Skin-Diseases--Infectious

The results of a clinical trial using a new preparation of Terracortril ointment and Terracortril cream without preservatives are reported. Apart from oxytetracycline 30 mg/g and 10 mg hydrocortisone alcohol/g, each drug contains polymyxin B 10,000 I.U./g. Of a total of 85 patients with primary and secondary pyodermias, 41 were completely or almost completely cured after application of ointment or cream respectively, 13 were largely, and 31 cases satisfactorily improved (see tables 1 and 2). The bacteriological findings are discussed. No skin irritations such as contact dermatitis were observed.

Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Dosage Forms; Drug Eruptions; Eczema; Female; Humans; Hydrocortisone; Male; Middle Aged; Ointments; Oxytetracycline; Pyoderma; Skin Diseases, Infectious

Topics: Bacitracin; Chlorine; Female; Furunculosis; Humans; Male; Mycoses; Neomycin; Ointments; Oxytetracycline; Skin Diseases, Infectious

Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dermatomycoses; Drug Tolerance; Enterobacteriaceae Infections; Erythema; Female; Humans; Male; Middle Aged; Ointments; Oxytetracycline; Placebos; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections; Time Factors

Topics: Adolescent; Adult; Bacterial Infections; Clinical Trials as Topic; Diabetes Complications; Doxycycline; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Oxytetracycline; Skin Diseases, Infectious; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus pyogenes; Thoracic Diseases; Time Factors

Topics: Adult; Animals; Child; Humans; Mice; Oxytetracycline; Skin Diseases, Infectious; Urethritis

Three cases of chronic infection with Borrelia burgdorferi are described. The patients presented with nodular or discoid fibrosis, partly in conjunction with acrodermatitis chronica atrophicans (ACA). Juxta-articular fibrotic nodules may develop within a few months of the onset of ACA. Nodular, discoid morphoea-like, and widespread cutaneous fibroses in chronic Borrelia infection may be provoked by trauma, surgery or electromagnetic radiation. They respond well to antibiotic therapy. These lesions offer an in vivo model for studying the evolution of immunologically induced fibrosis.

Topics: Adult; Borrelia burgdorferi Group; Female; Fibrosis; Humans; Immunoglobulin G; Lyme Disease; Male; Middle Aged; Oxytetracycline; Penicillin G Procaine; Penicillin V; Skin Diseases, Infectious

Topics: Actinomycetales; Actinomycetales Infections; Animals; Cattle; Cattle Diseases; Epidermis; Oxytetracycline; Penicillin G; Penicillin G Procaine; Skin Diseases, Infectious

Topics: Aerosols; Candidiasis, Cutaneous; Escherichia coli Infections; Humans; Oxytetracycline; Polymyxins; Powders; Proteus Infections; Pseudomonas Infections; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections

Topics: Administration, Topical; Aerosols; Anti-Inflammatory Agents; Female; Humans; Hydrocortisone; Hypersensitivity; Male; Neomycin; Oxytetracycline; Skin Diseases; Skin Diseases, Infectious

Topics: Abattoirs; Adult; Animals; Anthrax; Cattle; Cattle Diseases; Doxycycline; Humans; Male; Occupational Diseases; Occupational Medicine; Oxytetracycline; Penicillins; Skin Diseases, Infectious; Zoonoses

Topics: Anti-Bacterial Agents; Chloramphenicol; Gonorrhea; Humans; Neomycin; Oxytetracycline; Penicillin Resistance; Penicillins; Skin Diseases, Infectious; Syphilis

Topics: Drug Stability; Emulsions; Glycols; Humans; Microbial Sensitivity Tests; Ointments; Oxytetracycline; Pharmaceutical Vehicles; Skin Absorption; Skin Diseases, Infectious; Solubility; Time Factors; Triglycerides; Ultraviolet Rays

Topics: Anti-Bacterial Agents; Gonorrhea; Humans; Oxytetracycline; Sexually Transmitted Diseases; Skin Diseases, Infectious; Syphilis; Syphilis, Latent

Topics: Dermatologic Agents; Gels; Humans; Hydrocortisone; Oxytetracycline; Polymyxins; Skin Diseases, Infectious; Wound Infection

Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Autoantibodies; Chloramphenicol; Chronic Disease; Eczema; Humans; Immunotherapy; Ointments; Oxytetracycline; Penicillin Resistance; Penicillins; Salicylates; Skin Diseases, Infectious; Staphylococcal Infections; Streptomycin; Tars; Zinc

Topics: Adult; Animals; Child; Demeclocycline; Humans; Mice; Oxytetracycline; Respiratory Tract Infections; Skin Diseases, Infectious; Tetracycline; Urinary Tract Infections

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Humans; Oxytetracycline; Polymyxin B; Skin Diseases; Skin Diseases, Infectious

Topics: Humans; Oxytetracycline; Skin Diseases; Skin Diseases, Infectious