oxytetracycline--anhydrous and Pseudomonas-Infections

Topics: Acute Radiation Syndrome; Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Diphtheria; Enterobacter aerogenes; Escherichia coli Infections; Oxytetracycline; Penicillin G; Penicillins; Pharmacology; Proteus Infections; Pseudomonas Infections; Radiation Injuries, Experimental; Rats; Research; Staphylococcal Infections; Streptococcal Infections; Streptomycin

Chronic infection with Pseudomonas aeruginosa is common in cystic fibrosis (CF) and certain strains are more transmissible and virulent than others. Of these, the Liverpool Epidemic Strain (LES) is highly transmissible and cross infection has been reported between patients with CF and healthy non-CF relatives. However, the risk of transmission from humans to animals is unknown. The first report of interspecies transmission of the LES strain of P aeruginosa from an adult patient with CF to a pet cat is described. This development further complicates the issue of infection control policies required to prevent the spread of this organism.

Topics: Animals; Animals, Domestic; Anti-Bacterial Agents; Cat Diseases; Cats; Chronic Disease; Cystic Fibrosis; Humans; Male; Middle Aged; Oxytetracycline; Pseudomonas aeruginosa; Pseudomonas Infections

Irrespective of the microbial agent, group III steroid solution cured external otitis efficiently in a rat model. The addition of antibiotic components to steroid solutions for the treatment of external otitis is of questionable validity.. External otitis, caused by infection with either Pseudomonas aeruginosa or Candida albicans, was established in a rat model and the treatment efficacy of a group III steroid solution was studied.. Three treatments were studied: (i) a group III steroid solution; (ii) a group I steroid combined with two antibiotic components; and (iii) a saline solution. A scoring scale was used to evaluate the characteristics of the ear canal skin. Bacteriological and fungal samples were collected for culturing and ear canal skin biopsies were taken for structural analyses.. It was possible to cause P. aeruginosa and C. albicans infections in an animal model. In the P. aeruginosa-infected animals, only the group III steroid treatment cured all the animals. In the C. albicans-infected animals, group III steroid treatment resolved external otitis faster than the other treatment modalities.

Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Betamethasone; Candidiasis; Colony-Forming Units Assay; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ear Canal; Hydrocortisone; Male; Otitis Externa; Oxytetracycline; Polymyxin B; Pseudomonas Infections; Rats; Treatment Outcome

Topics: Accidents, Occupational; Anti-Bacterial Agents; Bone Resorption; Finger Injuries; Humans; Male; Metallurgy; Middle Aged; Oxytetracycline; Pseudomonas Infections

Topics: Administration, Topical; Adult; Drug Combinations; Female; Foot Dermatoses; Humans; Intertrigo; Male; Middle Aged; Oxytetracycline; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections

Combinations of EDTA-tromethamine and 7 antimicrobial agents (chloramphenicol, nalidixic acid, oxytetracycline, penicillin, polymyxin-B, streptomycin, and triple sulfa) were tested for synergistic activities against Pseudomonas aeruginosa. Three in vitro tests were used, including minimal inhibitory concentrations of the drugs, a 2-dimensional Microtiter checkerboard technique, and bacterial inhibition studies. A synergistic inhibitory action was observed with combinations of EDTA-tromethamine plus penicillin and EDTA-tromethamine plus oxytetracycline. When chloramphenicol, streptomycin, nalidixic acid, polymyxin-B, or triple sulfa was mixed with EDTA-tromethamine, synergistic action did not occur.

Topics: Animals; Anti-Bacterial Agents; Dog Diseases; Dogs; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Edetic Acid; Otitis Externa; Oxytetracycline; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Tromethamine

Topics: Humans; Oxytetracycline; Proteus Infections; Pseudomonas Infections; Urinary Tract Infections

Topics: Aerosols; Candidiasis, Cutaneous; Escherichia coli Infections; Humans; Oxytetracycline; Polymyxins; Powders; Proteus Infections; Pseudomonas Infections; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections

Germs in patients suffering from nonspecific odontogenous infections described in a previous paper were analysed with regard to their resistance to chemotherapy (1964 to 1971). At the same time it was discovered that in the bacteria groups: staphyloccocus aureus, streptococci and pneumococci and enterobacteriaceae plus pseudomonas (344 strains) their sensitivity to penicillin, streptomycin, chloramphenicol, oxytetracyclin, erythromycin, polymyxin B and nifurantin varied in several and significant ways. Significant changes were established in the resistance of staphylococcus aureus to all the potentially effective antibiotics, while from 1969 to 1971 the strains with the least resistance appeared. In the 1970 to 1971 period strepto- and pneumococci showed insensitivity to penicillin and streptomycin more frequently than before. From 1969 to 1971 entero-bacteriaceae and pseudomonas also showed evidence of increasing loss of sensitivity to chloramphenicol and oxytetracyclin, whereas the frequency of strains resistant to polymyxin B and nifurantine diminished. The findings are being discussed.

Topics: Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Enterobacteriaceae Infections; Erythromycin; Focal Infection, Dental; Humans; Microbial Sensitivity Tests; Nitrofurantoin; Oxytetracycline; Penicillin Resistance; Penicillins; Pneumococcal Infections; Polymyxins; Pseudomonas Infections; Staphylococcal Infections; Streptococcal Infections; Streptomycin

Pseudomonas aeruginosa was isolated from the viscera of diseased and dead birds (young and adult chickens) as well as from 9 poultry houses on seven farms. Its typing was performed on the basis of the blue-green coloration of the cultures, their hemolytic activity, the pleasant odour of lime-tree, the growth in culturing at 42 degrees C, the presence of the pyocianin pigment, and the positive results of the cytochromoxidase test after Gaby and Hadley and the biochemical test after Kovacs. The pathogenicity of the agent was demonstrated through the experimental parenteral infection of chicks, albino mice, and guinea pigs. Pseudomonas aeruginosa cultures showed weak sensitivity and good resistance to the various drugs tested. Most active proved streptomycin, kanamycin, and spectam.

Topics: Ampicillin; Animals; Chickens; Chloramphenicol; Drug Combinations; Furazolidone; Guinea Pigs; Kanamycin; Mice; Oleandomycin; Oxytetracycline; Penicillin Resistance; Penicillins; Poultry Diseases; Pseudomonas aeruginosa; Pseudomonas Infections; Spectinomycin; Streptomycin; Sulfadiazine; Sulfamerazine; Sulfathiazoles

Topics: Drug Synergism; Female; Humans; Male; Microbial Sensitivity Tests; Oxytetracycline; Polymyxins; Pseudomonas Infections; Urinary Tract Infections

Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Burns; Chloramphenicol; Dexamethasone; Gentamicins; Humans; Oxytetracycline; Polymyxins; Prednisolone; Pseudomonas Infections; Shock, Septic; Skin Transplantation; Transplantation, Homologous

Topics: Ampicillin; Anti-Bacterial Agents; Carbenicillin; Chloramphenicol; Colistin; Framycetin; Humans; Microbial Sensitivity Tests; Neomycin; Otorhinolaryngologic Diseases; Oxytetracycline; Penicillin Resistance; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Streptomycin

Topics: Adult; Aged; Anti-Bacterial Agents; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Oxytetracycline; Pseudomonas Infections; Staphylococcal Infections

Topics: Anti-Bacterial Agents; Colistin; Drug Synergism; Humans; Oxytetracycline; Polymyxins; Prognosis; Pseudomonas aeruginosa; Pseudomonas Infections

Topics: Anti-Bacterial Agents; Boric Acids; Child; Gentamicins; Germany, West; Humans; Methylene Blue; Microbial Sensitivity Tests; Neomycin; Oxytetracycline; Penicillins; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Rosaniline Dyes; Seasons

Topics: Bacteriophage Typing; Chloramphenicol; Germany, East; Hospital Departments; Humans; Lysogeny; Microbial Sensitivity Tests; Oxytetracycline; Pseudomonas aeruginosa; Pseudomonas Infections; Streptomycin

Topics: Animals; Bacteria; Colistin; Gentamicins; Mice; Microbial Sensitivity Tests; Microscopy, Electron; Oxytetracycline; Penicillins; Proteus; Proteus Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Shigella; Staphylococcus

Topics: Anti-Bacterial Agents; Drug Synergism; Gentamicins; Humans; Microbial Sensitivity Tests; Oxytetracycline; Penicillins; Pseudomonas; Pseudomonas Infections; Rifampin

Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Clostridium Infections; Debridement; Guinea Pigs; Kanamycin; Military Medicine; Oxytetracycline; Penicillins; Pseudomonas Infections; Soil Microbiology; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Wound Infection

Topics: Ampicillin; Animals; Anti-Infective Agents; Chloramphenicol; Immunization, Passive; Kanamycin; Mice; Nalidixic Acid; Neomycin; Oxazoles; Oxytetracycline; Penicillin G; Polymyxins; Proteus Infections; Pseudomonas Infections; Pyelonephritis; Sulfadiazine; Sulfisoxazole

Topics: Animals; Aqueous Humor; Biological Assay; Blindness; Colistin; Dogs; Eye Diseases; Inflammation; Oxytetracycline; Perfusion; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus; Uveitis; Vitreous Body

Topics: Animals; Anti-Infective Agents, Local; Colistin; Dihydrostreptomycin Sulfate; Female; Genital Diseases, Female; Gentamicins; Horse Diseases; Horses; Hydrocortisone; Infertility, Female; Nitrofurantoin; Novobiocin; Oxytetracycline; Penicillin G; Penicillin G Procaine; Penicillins; Polymyxins; Povidone; Pregnancy; Pregnancy, Animal; Pseudomonas Infections

Topics: Anemia; Chloramphenicol; Chlorpromazine; Eye; Glutethimide; Herpes Zoster; Herpes Zoster Ophthalmicus; Hodgkin Disease; Lung Abscess; Mechlorethamine; Meprobamate; Nitrofurantoin; Novobiocin; Ophthalmology; Oxytetracycline; Pentobarbital; Polymyxins; Pseudomonas Infections; Quinine; Retina; Sepsis; Streptomycin; Toxicology

Topics: Granuloma; Humans; Laryngoscopy; Oxytetracycline; Postoperative Complications; Pseudomonas Infections; Staphylococcal Infections; Surgical Wound Infection; Tomography; Tomography, X-Ray Computed; Tracheal Stenosis; Tracheotomy

Topics: Abortion, Septic; Anti-Bacterial Agents; Bile Ducts; Chloramphenicol; Emetine; Escherichia coli Infections; Female; Humans; Kanamycin; Neomycin; Oxytetracycline; Paraplegia; Penicillins; Peritonitis; Pregnancy; Pressure Ulcer; Pseudomonas Infections; Pyelonephritis; Pyoderma; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline

Topics: Anti-Bacterial Agents; Clostridium perfringens; Escherichia coli Infections; Oxytetracycline; Pharmacology; Proteus Infections; Pseudomonas Infections; Rabbits; Research; Staphylococcal Infections; Wound Healing; Wound Infection

Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Child; Chlortetracycline; Cross Infection; Humans; Infant; Leukocyte Count; Neomycin; Oxytetracycline; Penicillins; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Statistics as Topic; Streptomycin

Topics: Cornea; Corneal Ulcer; Drug Therapy; Edetic Acid; Humans; Ophthalmic Solutions; Oxytetracycline; Penicillins; Polymyxins; Pseudomonas; Pseudomonas Infections; Streptomycin

A virulent organism of the genus Pseudomonas was isolated from the white catfish, Ictalurus catus. The bacterium was pathogenic to all species of fish tested. Symptoms of the disease, physiological characteristics of the pathogen, and treatment methods are presented. Kanamycin injected intraperitoneally or oxytetracycline used as a feed additive was effective in controlling the disease. The growth and biochemical characteristics do not fit any description in Bergey's Manual, but the organism appears to be closely related to P. fluorescens.

Topics: Animals; Culture Media; Drug Therapy; Fishes; Ictaluridae; Kanamycin; Oxytetracycline; Pseudomonas Infections

Topics: Alcaligenes; Alcohols; Anti-Infective Agents; Chloramphenicol; Classification; Enterococcus faecalis; Escherichia coli Infections; Fermentation; Humans; Inositol; Nitrofurantoin; Oxytetracycline; Pseudomonas Infections; Streptococcal Infections; Streptomycin; Sucrose; Sulfathiazoles; Urinary Tract Infections; Urine

Forty cases of gonococcal urethritis were treated with oxytetracycline using various dosage schedules; there were 37 cures and three failures. The most convenient and most effective dosage was found to be 250 mg. oxytetracycline, given as a single intramuscular injection of 5 c.c.A series of 40 patients with non-gono-coccal urethritis was also collected. Two cases of urethritis due to Trichomonas vaginalis and two due to Candida albicans were removed from the series. Of the 36 cases which remained, cure was obtained with the use of oxytetracycline in different dosages in 30 cases; six cases were failures. The dosage which gave the best result in the therapy of non-gonococcal urethritis was 250 mg. oxytetracycline (5 c.c.), given as a single intramuscular injection, plus 250 mg. orally, four times a day for four days.The effectiveness of oxytetracycline in the treatment of urethritis has not decreased.

Topics: Candidiasis; Gonorrhea; Humans; Male; Oxytetracycline; Proteus Infections; Pseudomonas Infections; Staphylococcal Infections; Streptococcal Infections; Trichomonas Infections; Trichomonas vaginalis; Urethritis

Topics: Cholesteatoma; Fungi; Humans; Labyrinth Diseases; Mycoses; Otitis Media; Otitis Media, Suppurative; Oxytetracycline; Polymyxin B; Polymyxins; Pseudomonas Infections; Radiography; Surgical Procedures, Operative; Toxicology

Topics: Burns; Candidiasis; Chloramphenicol; Chlortetracycline; Escherichia coli Infections; Humans; Influenza, Human; Klebsiella; Oximetry; Oxygen Inhalation Therapy; Oxytetracycline; Penicillins; Pneumococcal Infections; Pneumonia; Proteus Infections; Pseudomonas Infections; Staphylococcal Infections; Statistics as Topic; Streptococcal Infections; Streptomycin; Sulfanilamide; Sulfanilamides

Topics: Anti-Bacterial Agents; Bacteriology; Chlortetracycline; Infections; Meningitis; Oxytetracycline; Pseudomonas aeruginosa; Pseudomonas Infections; Streptomycin