oxytetracycline--anhydrous and Porphyrias

oxytetracycline--anhydrous has been researched along with Porphyrias* in 2 studies

Other Studies

2 other study(ies) available for oxytetracycline--anhydrous and Porphyrias

Article	Year
The influence of porphyrogenic drugs on the glyoxalase enzymes. Research communications in chemical pathology and pharmacology, 1993, Volume: 82, Issue:3 A variety of drugs, known to induce acute attacks in porphyric patients has been found to inhibit the glyoxalase pathway. Glyoxalase I is competitively inhibited by sulphadimidine, oxytetracycline, chloramphenicol, etc. Allylisopropyl acetamide (AIA) seems to inhibit glyoxalase II. This inhibition could play a contributing role in the overproduction of porphyrins in porphyria and thus help explain the mechanism of induction of porphyric attacks. The results indicate, that the Heme pathway and the glyoxalase cycle are closely connected. Topics: Allylisopropylacetamide; Barbiturates; Chloramphenicol; Diazepam; Erythrocytes; Heme; Hemoglobins; Humans; Kinetics; Lactoylglutathione Lyase; Oxytetracycline; Porphyrias; Protoporphyrins; Spectrophotometry, Ultraviolet; Sulfamethazine; Thiolester Hydrolases	1993
Skin changes resembling hepatic cutaneous porphyria induced by oxytetracycline photosensitization. Clinical and experimental dermatology, 1980, Volume: 5, Issue:3 Topics: Acne Vulgaris; Adult; Female; Humans; Oxytetracycline; Photosensitivity Disorders; Porphyrias	1980

Article

Year

The influence of porphyrogenic drugs on the glyoxalase enzymes.

Research communications in chemical pathology and pharmacology, 1993, Volume: 82, Issue:3

A variety of drugs, known to induce acute attacks in porphyric patients has been found to inhibit the glyoxalase pathway. Glyoxalase I is competitively inhibited by sulphadimidine, oxytetracycline, chloramphenicol, etc. Allylisopropyl acetamide (AIA) seems to inhibit glyoxalase II. This inhibition could play a contributing role in the overproduction of porphyrins in porphyria and thus help explain the mechanism of induction of porphyric attacks. The results indicate, that the Heme pathway and the glyoxalase cycle are closely connected.

Topics: Allylisopropylacetamide; Barbiturates; Chloramphenicol; Diazepam; Erythrocytes; Heme; Hemoglobins; Humans; Kinetics; Lactoylglutathione Lyase; Oxytetracycline; Porphyrias; Protoporphyrins; Spectrophotometry, Ultraviolet; Sulfamethazine; Thiolester Hydrolases

1993

Skin changes resembling hepatic cutaneous porphyria induced by oxytetracycline photosensitization.

Clinical and experimental dermatology, 1980, Volume: 5, Issue:3

Topics: Acne Vulgaris; Adult; Female; Humans; Oxytetracycline; Photosensitivity Disorders; Porphyrias

1980