oxytetracycline--anhydrous and Jaundice

Eperythrozoonosis was diagnosed in 23 herds of swine. Icterus and anemia were the major diagnostic criteria, with low packed cell volumes confirming the clinical impression of anemia. Indirect hemagglutination titers provided an indirect measure of infection rates and appeared to correlate positively with severity of signs. Treatment with oxytetracycline and arsanilic acid controlled the disease, but only when combined with efforts to limit transmission of the causative organism through control of lice.

Topics: Anaplasmataceae Infections; Anemia; Animals; Arsanilic Acid; Female; Insect Control; Jaundice; Mycoplasma Infections; Oxytetracycline; Phthiraptera; Pregnancy; Pregnancy Complications, Infectious; Swine; Swine Diseases

A colony of nude mice was maintained under controlled standards of care for 12 months, at which time a rapidly escalating liver disease developed in the animals, characterized by jaundice, emaciation, and rapid death. Histologically, the livers had swollen, vacuolated hepatic cells and increased numbers of enlarged Kupffer cells. Mouse hepatitis virus was not isolated from the livers of sick mice. Although the nature of the lesions suggested toxicity, efforts to reproduce the lesions by increased exposure to chemical compounds used for colony husbandry were unsuccessful. A definitive determination of the causative agent was not made.

Topics: Animals; Hepatitis, Animal; Jaundice; Liver; Mice; Mice, Nude; Oxytetracycline; Peracetic Acid; Rodent Diseases

Topics: Adolescent; Chloramphenicol; Cysts; Echinococcosis; Echinococcosis, Hepatic; Fever; Jaundice; Liver; Oxytetracycline; Pain; Penicillins; Postoperative Complications; Rifamycins; Sepsis; Streptomycin; Suppuration; Surgical Procedures, Operative

Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Diet; Diet Therapy; Hepatitis; Hepatitis A; Humans; Jaundice; Oxytetracycline; Pathology; Prednisone; Prognosis; Tetracycline; Therapeutics; Vitamin K; Vitamins

Topics: Acidosis; Cesarean Section; Fatty Liver; Female; Hematemesis; Humans; Hypoproteinemia; Hypotension; Hysterectomy; Jaundice; Liver Diseases; Melena; Oxytetracycline; Pathology; Placenta Previa; Pneumonia; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Pregnancy Complications; Tetracycline; Toxicology

Topics: Anaplasmosis; Anemia; Animals; Chlortetracycline; Jaundice; Louisiana; Oxytetracycline