oxytetracycline--anhydrous and Dental-Plaque

The aim of the present experiment was to study if the quality of the titanium surface is a decisive factor for osseointegration and re-osseointegration.. 2 Labrador dogs were used. The mandibular 1st molars and all premolars were removed bilaterally. 3 months later, 1 standard fixture and 3, 2-part "test fixtures" were installed in each side of the mandible. The text fixtures consisted of 1 6-mm long apical and 1 4-mm long coronal part connected with an internal screw. After 4 months, abutment connection was performed. 5 months later, a period of experimental peri-implantitis was initiated during which about 50% of the supporting bone tissue was lost. The dogs were later subjected to a treatment that included (i) systemic administration of antibiotics and (ii) surgical debridement of all implant sites. The abutments and the coronal parts of the text fixtures were removed. All parts of the exposed portion of the standard fixtures, the connecting screw and the apical part of the test fixtures were meticulously cleaned by mechanical means. A pristine, coronal fixture part was via the connecting screw attached to the apical fixture part of each text fixture. All fixtures were submerged. 2 weeks later, a fluorochrome was injected intravenously. After 4 months, biopsies of the implant sites were dissected and prepared for ground sectioning and analysis.. It was demonstrated that re-osseointegration failed to occur to implant surfaces (standard) exposed to bacterial contamination, but did consistently occur at sites where a pristine implant component was placed in the bone defect following surgical debridement.. The above findings seem to imply that the quality of the titanium surface is of decisive importance for both osseointegration and re-osseointegration.

Topics: Alveolar Bone Loss; Amoxicillin; Animals; Bicuspid; Coloring Agents; Curettage; Debridement; Dental Abutments; Dental Implantation, Endosseous; Dental Implants; Dental Plaque; Dental Prosthesis Design; Dogs; Fluorescent Dyes; Molar; Osseointegration; Osteogenesis; Oxytetracycline; Penicillins; Periodontitis; Reoperation; Surface Properties; Titanium; Tolonium Chloride; Tooth Extraction; Wound Healing

The clinical development of broken mouth over a single reproductive year and the effect of two broad spectrum antibacterial agents upon it was followed in 72 Scottish Blackface ewes aged between two and three years. Using a number of dental health indices especially developed for the purpose, the amount of gingivitis, tooth movement, gum recession and pocketing were quantified and graphed for both the whole population and each group in the drug trial. All clinical features except movement fluctuated significantly with time, the fluctuations often being associated with nutritional or other environmental factors. Despite the extended use of large doses of two antimicrobial agents no significant reduction in the amount of clinical gingivitis or pocketing was evident.

Topics: Animals; Body Weight; Dental Plaque; Female; Gingiva; Metronidazole; Oxytetracycline; Periodontal Diseases; Periodontal Index; Sheep; Sheep Diseases; Time Factors

Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis; Humans; Mouthwashes; Oxytetracycline; Periodontal Diseases; Tooth Discoloration; Toothbrushing

Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis; Humans; Mouthwashes; Oxytetracycline; Periodontal Diseases; Tooth Discoloration; Toothbrushing