oxytetracycline--anhydrous and Bacteriuria

Topics: Absorption; Acne Vulgaris; Bacteria; Bacteriuria; Bronchial Diseases; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlortetracycline; Demeclocycline; Drug Eruptions; Humans; Infections; Kidney Diseases; Methacycline; Oxytetracycline; Protein Binding; Tetracycline; Tooth Discoloration

Topics: Adult; Anti-Bacterial Agents; Bacteriuria; Drug Resistance, Microbial; Female; Humans; Klebsiella Infections; Oxytetracycline; Pregnancy; Pregnancy Complications, Infectious; Pyelonephritis; Sepsis

To evaluate antibiotics for treatment of cattle with leptospirosis caused by Leptospira borgpetersenii serovar hardjo.. Randomized controlled trial.. 42 healthy mixed-breed cattle.. Cattle were inoculated via conjunctival instillation with L. borgpetersenii serovar hardjo. After infection and urinary shedding of L. borgpetersenii were confirmed, cattle were treated with various antibiotics. To determine effectiveness of antibiotic treatment, urinary shedding of L. borgpetersenii was monitored for 4 to 6 weeks after administration of antibiotics, using darkfield microscopic examination, microbial culture, immunofluorescence testing, and a polymerase chain reaction assay.. All inoculated cattle developed leptospirosis and shed leptospires in their urine. The following antibiotic treatments resulted in elimination of urinary shedding of leptospires: a single injection of oxytetracycline (20 mg/kg 19 mg/lb] of body weight, IM), tilmicosin (10 mg/kg [4.5 mg/lb], SC), or a combination product that contained dihydrostreptomycin-penicillin G (25 mg/kg [11.4 mg/lb], IM) or multiple injections of ceftiofur sodium (2.2 or 5 mg/kg [1 or 2.3 mg/lb], IM, once daily for 5 days, or 20 mg/kg, IM, once daily for 3 days).. Successful resolution of leptospirosis in cattle by administration of dihydrostreptomycin-penicillin G confirms results obtained by other investigators. Three other antibiotics (oxytetracycline, tilmicosin, and ceftiofur) also were effective for resolving leptospirosis and may be useful substitutes for dihydrostreptomycin, an antibiotic that is no longer available for use in food-producing animals in the United States. Cost, safety, and withdrawal times of these various treatment options need to be considered.

Topics: Animals; Anti-Bacterial Agents; Bacteriuria; Cattle; Cattle Diseases; Cephalosporins; Dihydrostreptomycin Sulfate; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Leptospira; Leptospirosis; Macrolides; Male; Oxytetracycline; Penicillin G; Polymerase Chain Reaction; Treatment Outcome; Tylosin

Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacteriuria; Biological Assay; Blood; Female; Humans; Male; Middle Aged; Oxytetracycline; Recurrence; Retrospective Studies; Time Factors; Urinary Tract Infections; Urine; Urography

Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Bacteriuria; Carbenicillin; Chloramphenicol; Depression, Chemical; Drug Antagonism; Drug Synergism; Erythromycin; Escherichia coli; Exudates and Transudates; Humans; Kanamycin; Methacycline; Novobiocin; Oxytetracycline; Proteus; Pseudomonas aeruginosa; Rifampin; Ristocetin; Sepsis; Sputum; Staphylococcus; Surgical Wound Infection

Topics: Adult; Bacteriuria; Blood Urea Nitrogen; Female; Humans; Male; Middle Aged; Oxytetracycline; Uremia

Topics: Aged; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Cephaloridine; Gentamicins; Humans; Male; Methacycline; Methenamine; Middle Aged; Nalidixic Acid; Nitrofurantoin; Oxytetracycline; Penicillin G; Postoperative Care; Postoperative Complications; Prospective Studies; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Sulfamethizole; Urethra; Urinary Tract Infections; Urine

Topics: Adolescent; Adult; Aged; Bacteriuria; Cephalothin; Chloramphenicol; Chronic Disease; Colistin; Drug Resistance, Microbial; Escherichia coli Infections; Female; Gentamicins; Humans; Kanamycin; Male; Methacycline; Middle Aged; Oxytetracycline; Proteus Infections; Rifampin; Sulfamethoxypyridazine; Urinary Tract Infections

Topics: Agar; Alcaligenes; Bacteria; Bacteriuria; Chloramphenicol; Diffusion; Doxycycline; Drug Resistance, Microbial; Escherichia coli; Haemophilus influenzae; Humans; Klebsiella; Methods; Microbial Sensitivity Tests; Oxytetracycline; Proteus; Pseudomonas; Respiratory System; Species Specificity; Staphylococcus; Streptococcus; Tetracycline

Topics: Bacteriuria; Carcinoma, Squamous Cell; Female; Genital Diseases, Female; Humans; Hysterectomy; Kidney Diseases; Kidney Function Tests; Neomycin; Oxytetracycline; Postoperative Complications; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Infectious; Pyelonephritis; Uterine Cervical Neoplasms

Topics: Bacteria; Bacteriological Techniques; Bacteriuria; Drug Resistance, Microbial; Humans; Methods; Oxytetracycline

Topics: Bacteriuria; Child; Child, Preschool; Chloramphenicol; Cytodiagnosis; Diagnosis, Differential; Humans; Infant; Nitrofurantoin; Oxytetracycline; Prognosis; Pyelonephritis; Streptomycin

Topics: Bacteriuria; Chloramphenicol; Drug Resistance, Microbial; Humans; Klebsiella; Klebsiella Infections; Nitrofurantoin; Oxytetracycline; Respiratory Tract Infections; Serotyping; Streptomycin; Suppuration

Topics: Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cephalosporins; Cephalothin; Chloramphenicol; Chlortetracycline; Demeclocycline; Escherichia coli; Gentamicins; Humans; Kanamycin; Klebsiella; Methacycline; Microbial Sensitivity Tests; Oxytetracycline; Penicillin G; Penicillins; Polymyxins; Proteus; Pseudomonas aeruginosa; Sepsis; Serratia; Streptomycin; Tetracycline