oxytetracycline--anhydrous and Animal-Diseases

Topics: Animal Diseases; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anti-Bacterial Agents; Bacitracin; Body Weight; Cattle; Chlortetracycline; Food Additives; Meat; Oxytetracycline; Penicillin G Procaine; Poultry; Sheep; Swine

The depletion times of enrofloxacin and its metabolite ciprofloxacin as well as sulfaquinoxaline and oxytetracycline were evaluated in broiler chickens that had been subjected to pharmacological treatment. The presence and residue levels of these drugs in muscle tissue were evaluated using an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method that was validated in this work. The results showed the presence of all antimicrobial residues; however, the presence of residues at concentrations higher than the drugs' maximum residue limit (MRL) of 100 μg kg-1 was found only during the treatment period for oxytetracycline and until two days after discontinuation of the medication for enrofloxacin, ciprofloxacin and sulfaquinoxaline. It was concluded that the residues of all antimicrobials were rapidly metabolized from the broiler muscles; after four days of withdrawal, the levels were lower than the limit of quantification (LOQ) of the method for the studied analytes.

Topics: Animal Diseases; Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Inactivation, Metabolic; Muscles; Oxytetracycline; Sulfaquinoxaline

Topics: Animal Diseases; Animals; Anti-Bacterial Agents; Daphnia; Lethal Dose 50; Oxytetracycline; Sulfadimethoxine; Sulfamethazine; Tylosin; Veterinary Medicine

Topics: Administration, Cutaneous; Animal Diseases; Animal Identification Systems; Animals; Animals, Newborn; Anti-Bacterial Agents; Cattle; Disease Outbreaks; Ear; England; Oxytetracycline; Papilloma; Skin Neoplasms

Topics: Animal Diseases; Animal Nutritional Physiological Phenomena; Animals; Chlortetracycline; Infections; Oleandomycin; Oxytetracycline; Tetracycline