oxyquinoline has been researched along with Neoplasms in 34 studies
Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.
quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "In studies of their anti-cancer properties, CQ has been proposed to elicit toxic intracellular copper accumulation and to trigger apoptotic cancer cell death through several possible pathways." | 1.56 | PBT2 acts through a different mechanism of action than other 8-hydroxyquinolines: an X-ray fluorescence imaging study. ( Dolgova, NV; Gagnon, KB; George, GN; Harris, HH; James, AK; Lai, B; Nichol, HK; Pickering, IJ; Sopasis, GJ; Summers, KL; Sylvain, NJ, 2020) |
| "Compound 4c might be utilized for cancer theranostic agents because of its significant quantum yield in water, high potency, selectivity and high cellular uptake in cancer cell lines." | 1.48 | Amberlite IR-120 (H) mediated "on water" synthesis of fluorescent Ruthenium(II)-arene 8-hydroxyquinoline complexes for cancer therapy and live cell imaging. ( De, S; Jacob, R; Maiti, S; Mondal, A; Moorthy, A; Paira, P; Sarkar, B; Sk, AK, 2018) |
| "In previous studies the anticancer potential of organoruthenium complex with 8-hydroxyquinoline ligand clioquinol was well established and we have decided to perform an extended biological evaluation (antibacterial and antitumor activity) of the whole series of halo-substituted analogs." | 1.48 | Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines. ( Bai, Y; Cadavid-Vargas, JF; Etcheverry, SB; He, W; Kljun, J; León, IE; Peršič, Š; Turel, I, 2018) |
| "More than 85% of (111)In remained in tumors, bound to cell cytoplasmic components of apparent molecular weights 250 and 6 kDa." | 1.32 | Role of lipid-soluble complexes in targeted tumor therapy. ( Coss, R; Howell, R; Leeper, DL; Liu, J; Rao, SP; Spana, G; Thakur, ML; Vassileva-Belnikolovska, D; Wachsberger, P, 2003) |
| "Twenty-five of 29 foci of bacterial infection were demonstrated on the leukocyte-labeled images (sensitivity of detection = 86%)." | 1.27 | In-111 labeled leukocytes: a review of problems in image interpretation. ( McAfee, JG; Samin, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (26.47) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 13 (38.24) | 24.3611 |
| 2020's | 7 (20.59) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Perez, C | 1 |
| Li, J | 1 |
| Parlati, F | 1 |
| Rouffet, M | 1 |
| Ma, Y | 1 |
| Mackinnon, AL | 1 |
| Chou, TF | 1 |
| Deshaies, RJ | 1 |
| Cohen, SM | 1 |
| Pape, VFS | 2 |
| Palkó, R | 1 |
| Tóth, S | 2 |
| Szabó, MJ | 1 |
| Sessler, J | 1 |
| Dormán, G | 1 |
| Enyedy, ÉA | 1 |
| Soós, T | 1 |
| Szatmári, I | 1 |
| Szakács, G | 2 |
| Cserepes, M | 1 |
| Türk, D | 1 |
| Gaál, A | 1 |
| Gera, M | 1 |
| Szabó, JE | 1 |
| Kucsma, N | 1 |
| Várady, G | 1 |
| Vértessy, BG | 1 |
| Streli, C | 1 |
| Szabó, PT | 1 |
| Tovari, J | 1 |
| Szoboszlai, N | 1 |
| Yang, QY | 1 |
| Cao, QQ | 1 |
| Zhang, YL | 1 |
| Xu, XF | 1 |
| Deng, CX | 1 |
| Kumar, R | 1 |
| Zhu, XM | 1 |
| Wang, XJ | 1 |
| Liang, H | 2 |
| Chen, ZF | 2 |
| Summers, KL | 1 |
| Dolgova, NV | 1 |
| Gagnon, KB | 1 |
| Sopasis, GJ | 1 |
| James, AK | 1 |
| Lai, B | 1 |
| Sylvain, NJ | 1 |
| Harris, HH | 1 |
| Nichol, HK | 1 |
| George, GN | 1 |
| Pickering, IJ | 1 |
| Gupta, R | 1 |
| Luxami, V | 1 |
| Paul, K | 1 |
| Wang, X | 1 |
| Niu, X | 1 |
| Zhang, X | 1 |
| Zhang, Z | 1 |
| Gao, X | 1 |
| Wang, W | 1 |
| Yuan, Z | 1 |
| Zheng, H | 1 |
| Zhu, T | 1 |
| Li, X | 1 |
| Wang, G | 1 |
| Jia, Q | 1 |
| Mondal, A | 1 |
| De, S | 1 |
| Maiti, S | 1 |
| Sarkar, B | 1 |
| Sk, AK | 1 |
| Jacob, R | 1 |
| Moorthy, A | 1 |
| Paira, P | 1 |
| Hampton, SE | 1 |
| Dore, TM | 1 |
| Schmidt, WK | 1 |
| Kljun, J | 2 |
| León, IE | 2 |
| Peršič, Š | 1 |
| Cadavid-Vargas, JF | 1 |
| Etcheverry, SB | 1 |
| He, W | 1 |
| Bai, Y | 1 |
| Turel, I | 2 |
| Ruiz, MC | 1 |
| Di Virgilio, AL | 1 |
| Yang, L | 2 |
| Zhang, J | 1 |
| Wang, C | 1 |
| Qin, X | 1 |
| Yu, Q | 1 |
| Zhou, Y | 1 |
| Liu, J | 2 |
| Jungwirth, U | 1 |
| Gojo, J | 1 |
| Tuder, T | 1 |
| Walko, G | 1 |
| Holcmann, M | 1 |
| Schöfl, T | 1 |
| Nowikovsky, K | 1 |
| Wilfinger, N | 1 |
| Schoonhoven, S | 1 |
| Kowol, CR | 1 |
| Lemmens-Gruber, R | 1 |
| Heffeter, P | 1 |
| Keppler, BK | 2 |
| Berger, W | 1 |
| Oliveri, V | 2 |
| Viale, M | 2 |
| Aiello, C | 2 |
| Vecchio, G | 2 |
| Zhai, S | 1 |
| Cui, QC | 1 |
| Sun, Y | 1 |
| Dou, QP | 2 |
| Yan, B | 2 |
| Giuffrida, ML | 1 |
| Rubush, DM | 1 |
| Morges, MA | 1 |
| Rose, BJ | 1 |
| Thamm, DH | 1 |
| Rovis, T | 1 |
| Liu, YC | 1 |
| Song, XY | 1 |
| Peng, Y | 1 |
| Qin, QP | 1 |
| Thakur, ML | 1 |
| Coss, R | 1 |
| Howell, R | 1 |
| Vassileva-Belnikolovska, D | 1 |
| Rao, SP | 1 |
| Spana, G | 1 |
| Wachsberger, P | 1 |
| Leeper, DL | 1 |
| HUEPER, WC | 1 |
| Hofheinz, RD | 1 |
| Dittrich, C | 1 |
| Jakupec, MA | 1 |
| Drescher, A | 1 |
| Jaehde, U | 1 |
| Gneist, M | 1 |
| Graf von Keyserlingk, N | 1 |
| Hochhaus, A | 1 |
| Daniel, KG | 1 |
| Chen, D | 1 |
| Schell-Frederick, E | 1 |
| Frühling, J | 1 |
| Van der Auwera, P | 1 |
| Van Laethem, Y | 1 |
| Klastersky, J | 1 |
| Dutcher, JP | 1 |
| Marienhagen, J | 1 |
| Hennemann, B | 1 |
| Andreesen, R | 1 |
| Eilles, C | 1 |
| Frost, P | 1 |
| Smith, J | 1 |
| Frost, H | 1 |
| Eichler, HG | 1 |
| Gasic, S | 1 |
| Korn, A | 1 |
| McAfee, JG | 1 |
| Samin, A | 1 |
| Boneu, A | 1 |
| Sié, P | 1 |
| Bugat, R | 1 |
| Caranobe, C | 1 |
| Eber, M | 1 |
| Cazenave, JP | 1 |
| Boneu, B | 1 |
| Lockshin, A | 1 |
| Mendoza, JT | 1 |
| Giovanella, BC | 1 |
| Stehlin, JS | 1 |
6 reviews available for oxyquinoline and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Insights of 8-hydroxyquinolines: A novel target in medicinal chemistry.
Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Chemistry, Pharmaceutical; Fungi; Humans; Ne | 2021 |
Rce1: mechanism and inhibition.
Topics: Animals; Endopeptidases; Endoplasmic Reticulum; Humans; Neoplasm Proteins; Neoplasms; Oxyquinoline; | 2018 |
Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer.
Topics: Antineoplastic Agents; Apoptosis; Clioquinol; Copper; Humans; Neoplasms; Neovascularization, Patholo | 2007 |
Labeled cells in patients with malignancy.
Topics: Agranulocytosis; Animals; Blood Transfusion; Cell Movement; Chromium Radioisotopes; Granulocytes; Ho | 1984 |
2 trials available for oxyquinoline and Neoplasms
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Early results from a phase I study on orally administered tris(8-quinolinolato)gallium(III) (FFC11, KP46) in patients with solid tumors--a CESAR study (Central European Society for Anticancer Drug Research--EWIV).
Topics: Administration, Oral; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; | 2005 |
27 other studies available for oxyquinoline and Neoplasms
| Article | Year |
|---|---|
Discovery of an Inhibitor of the Proteasome Subunit Rpn11.
Topics: Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Humans; Models, Molecular; Neoplasm | 2017 |
Structure-Activity Relationships of 8-Hydroxyquinoline-Derived Mannich Bases with Tertiary Amines Targeting Multidrug-Resistant Cancer.
Topics: Antineoplastic Agents; Chelating Agents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Human | 2022 |
Unshielding Multidrug Resistant Cancer through Selective Iron Depletion of P-Glycoprotein-Expressing Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Cell | 2020 |
Synthesis, structural characterization and antitumor activity of six rare earth metal complexes with 8-hydroxyquinoline derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cisplatin; Coordination Complexes; H | 2020 |
PBT2 acts through a different mechanism of action than other 8-hydroxyquinolines: an X-ray fluorescence imaging study.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Copper; Humans; Neoplasms; Optical Ima | 2020 |
Construction of an AuHQ nano-sensitizer for enhanced radiotherapy efficacy through remolding tumor vasculature.
Topics: Animals; Cell Survival; Female; Gold; Hep G2 Cells; Heterografts; Human Umbilical Vein Endothelial C | 2021 |
Immobilization of β-Cyclodextrin-Conjugated Lactoferrin onto Polymer Monolith for Enrichment of Ga in Metabolic Residues of Ga-Based Anticancer Drugs.
Topics: Antineoplastic Agents; beta-Cyclodextrins; Gallium; Humans; Lactoferrin; Limit of Detection; Neoplas | 2017 |
Amberlite IR-120 (H) mediated "on water" synthesis of fluorescent Ruthenium(II)-arene 8-hydroxyquinoline complexes for cancer therapy and live cell imaging.
Topics: Antineoplastic Agents; Binding Sites; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Coordination Co | 2018 |
Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines.
Topics: A549 Cells; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Humans; Neoplasms; Organometall | 2018 |
Comparative antitumor studies of organoruthenium complexes with 8-hydroxyquinolines on 2D and 3D cell models of bone, lung and breast cancer.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Hu | 2019 |
Interaction between 8-hydroxyquinoline ruthenium(II) complexes and basic fibroblast growth factors (bFGF): inhibiting angiogenesis and tumor growth through ERK and AKT signaling pathways.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Coordina | 2014 |
Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46.
Topics: Animals; Caco-2 Cells; Calpain; Cell Adhesion; Cell Line, Tumor; Female; Humans; Integrins; Mice; Mi | 2014 |
New 8-hydroxyquinoline galactosides. The role of the sugar in the antiproliferative activity of copper(II) ionophores.
Topics: A549 Cells; Cell Proliferation; Copper; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Iono | 2015 |
Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells.
Topics: Antineoplastic Agents; Biological Transport; Cell Proliferation; Clioquinol; Copper; Drug Screening | 2010 |
Gluconjugates of 8-hydroxyquinolines as potential anti-cancer prodrugs.
Topics: Antineoplastic Agents; beta-Glucosidase; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays | 2012 |
An asymmetric synthesis of 1,2,4-trioxane anticancer agents via desymmetrization of peroxyquinols through a Brønsted acid catalysis cascade.
Topics: Acids; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cell Survival; Heterocyclic Compounds; Hu | 2012 |
Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato-lanthanides.
Topics: Cell Line, Tumor; Cell Survival; Circular Dichroism; Coordination Complexes; Crystallography, X-Ray; | 2013 |
Role of lipid-soluble complexes in targeted tumor therapy.
Topics: Animals; Breast Neoplasms; Cell Line; Colorectal Neoplasms; Dose-Response Relationship, Radiation; D | 2003 |
EXPERIMENTAL STUDIES ON 8-HYDROXYQUINOLINE IN RATS AND MICE.
Topics: Adenocarcinoma; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Mice; Neoplasms; N | 1965 |
111Indium-oxine-labeled leukocytes in the diagnosis of localized infection in patients with neoplastic disease.
Topics: Bacterial Infections; Bone Neoplasms; Diagnosis, Differential; False Negative Reactions; Female; Hum | 1984 |
111In-oxine labelling of tumour-cytotoxic macrophages generated in vitro from circulating blood monocytes: an in vitro evaluation.
Topics: Cell Survival; Cytotoxicity, Immunologic; Humans; Immunotherapy, Adoptive; In Vitro Techniques; Indi | 1995 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
The radiolabeling of lymphocytes and tumor cells with 111indium.
Topics: Animals; Cell Membrane; Cytoplasm; Indium; Isotope Labeling; Leukocytes; Mice; Mice, Inbred BALB C; | 1978 |
[Carrier systems for drugs--a new principle in drug therapy?].
Topics: Blood Platelets; Drug Therapy; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Liposomes; Macr | 1985 |
In-111 labeled leukocytes: a review of problems in image interpretation.
Topics: Abdomen; Abscess; Adult; Aged; Bacterial Infections; False Positive Reactions; Female; Humans; Indiu | 1985 |
Platelet regeneration time after aspirin ingestion and platelet survival time after labelling with 51chromium or 111indium oxine--a comparative study.
Topics: Adult; Aspirin; Blood Platelets; Cell Survival; Chromium Radioisotopes; Female; Humans; Hydroxyquino | 1985 |
111Indium labeling of cultured human tumor cells.
Topics: Animals; Cell Line; Cell Survival; Deoxyuridine; Diphtheria Toxin; Edetic Acid; Half-Life; Humans; H | 1985 |