Page last updated: 2024-10-21

oxyquinoline and Breast Neoplasms

oxyquinoline has been researched along with Breast Neoplasms in 6 studies

Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.
quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
" 8Q showed some antitumor activity alone but had much better therapeutic effect and relapse prevention when combined with paclitaxel than either 8Q or paclitaxel alone in both MCF7 and MDA-MB-435 xenograft models."5.35Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model. ( Gu, P; Margolick, JB; Yin, D; Zhang, H; Zhang, Y; Zhou, J, 2009)
" 8Q showed some antitumor activity alone but had much better therapeutic effect and relapse prevention when combined with paclitaxel than either 8Q or paclitaxel alone in both MCF7 and MDA-MB-435 xenograft models."1.35Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model. ( Gu, P; Margolick, JB; Yin, D; Zhang, H; Zhang, Y; Zhou, J, 2009)
"More than 85% of (111)In remained in tumors, bound to cell cytoplasmic components of apparent molecular weights 250 and 6 kDa."1.32Role of lipid-soluble complexes in targeted tumor therapy. ( Coss, R; Howell, R; Leeper, DL; Liu, J; Rao, SP; Spana, G; Thakur, ML; Vassileva-Belnikolovska, D; Wachsberger, P, 2003)
"In the animal bearing breast carcinoma, uptake occurred in the tumor, lungs and in a draining sinus in the left axilla."1.27In vivo studies of 111In-labelled canine lymphocytes. ( Benua, RS; Robinson, LW; Yeh, SD, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Ma, L1
Xuan, X1
Fan, M1
Zhang, Y2
Yuan, G1
Huang, G1
Liu, Z1
Kessel, SL1
Chan, LL1
Zhou, J1
Zhang, H1
Gu, P1
Margolick, JB1
Yin, D1
Thakur, ML1
Coss, R1
Howell, R1
Vassileva-Belnikolovska, D1
Liu, J1
Rao, SP1
Spana, G1
Wachsberger, P1
Leeper, DL1
Viola-Rhenals, M1
Rieber, MS1
Rieber, M1
Robinson, LW1
Yeh, SD1
Benua, RS1

Other Studies

6 other studies available for oxyquinoline and Breast Neoplasms

ArticleYear
A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis.
    Apoptosis : an international journal on programmed cell death, 2022, Volume: 27, Issue:7-8

    Topics: Apoptosis; Breast Neoplasms; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum Stress; Extracellul

2022
A High-Throughput Image Cytometry Method for the Formation, Morphometric, and Viability Analysis of Drug-Treated Mammospheres.
    SLAS discovery : advancing life sciences R & D, 2020, Volume: 25, Issue:7

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Female; High-Thr

2020
Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model.
    Breast cancer research and treatment, 2009, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease

2009
Role of lipid-soluble complexes in targeted tumor therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:8

    Topics: Animals; Breast Neoplasms; Cell Line; Colorectal Neoplasms; Dose-Response Relationship, Radiation; D

2003
Suppression of survival in human SKBR3 breast carcinoma in response to metal-chelator complexes is preferential for copper-dithiocarbamate.
    Biochemical pharmacology, 2006, Mar-14, Volume: 71, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chelating Agents; Copper;

2006
In vivo studies of 111In-labelled canine lymphocytes.
    International journal of nuclear medicine and biology, 1984, Volume: 11, Issue:1

    Topics: Animals; Breast Neoplasms; Dogs; Female; Indium; Isotope Labeling; Lymph Nodes; Lymphocytes; Organom

1984