Page last updated: 2024-11-06

oxyphenonium and Asthma

oxyphenonium has been researched along with Asthma in 3 studies

Oxyphenonium: A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"The protective effects of oxyphenonium bromide, terbutaline and theophylline were compared in 8 asthmatic patients by determination of the degree of non-specific airway reactivity after 1 week of oral treatment according to a fixed dose scheme in a double-blind random order: oxyphenonium bromide 3 X 10 mg; terbutaline 3 X 5 mg; theophylline 2 X 300 mg and placebo."5.05Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol. ( de Vries, K; de Zeeuw, RA; Greving, J; Jonkman, JH; Koëter, GH; Leferink, J; Meurs, H; Sluiter, HJ, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BUYTENDIJK, HJ1
MAESEN, F1
van Bork, LE1
Jonkman, JH2
Greving, JE1
Orie, NG1
Peset, R1
de Vries, K2
de Zeeuw, RA2
Koëter, GH1
Meurs, H1
Greving, J1
Leferink, J1
Sluiter, HJ1

Trials

1 trial available for oxyphenonium and Asthma

ArticleYear
Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:4

    Topics: Acetylcholine; Administration, Oral; Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests

1984

Other Studies

2 other studies available for oxyphenonium and Asthma

ArticleYear
[VALUE OF ANTRENYL AS A BRONCHODILATOR. COMPARATIVE STUDY WITH RESPECT TO AMINOPHYLLINE].
    Le Poumon et le coeur, 1963, Volume: 19

    Topics: Aminophylline; Asthma; Bronchodilator Agents; Geriatrics; Humans; Male; Oxyphenonium; Parasympatholy

1963
Relationship between plasma concentration and the pulmonary and cardiac effects of three anticholinergics.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Asthma; Bronchodilator Agents; Emphysema; Humans; Injections, Intramuscular; Injections, Intravenous

1984