oxyphenbutazone has been researched along with Stevens-Johnson Syndrome in 7 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
Excerpt | Relevance | Reference |
---|---|---|
"The authors report 18 children with toxic epidermal necrolysis (T." | 1.27 | [Toxic epidermal necrolysis in children (Lyell's syndrome). Apropos of 18 cases]. ( Cloup, M; De Frost, Y; Hubert, P; Marsol, P; Richard, P; Roujeau, JC; Teillac, D, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Zeile, G | 1 |
Wandel, E | 1 |
Bork, K | 1 |
Krönig, B | 1 |
Neetens, A | 1 |
Zelencova, L | 1 |
Teillac, D | 1 |
Marsol, P | 1 |
Richard, P | 1 |
Hubert, P | 1 |
Roujeau, JC | 2 |
Cloup, M | 1 |
De Frost, Y | 1 |
Albengres, E | 1 |
Moritz, S | 1 |
Piacentino, A | 1 |
Cuny, M | 1 |
Revuz, J | 1 |
Touraine, R | 1 |
Kimmig, J | 1 |
Bruinsma, W | 1 |
Ritland, S | 1 |
7 other studies available for oxyphenbutazone and Stevens-Johnson Syndrome
Article | Year |
---|---|
[Lyell's syndrome with transient bone marrow depression caused by oxyphenebutazone].
Topics: Adult; Anemia; Blood Cell Count; Bone Marrow Cells; Bone Marrow Diseases; Humans; Male; Oxyphenbutaz | 1979 |
Toxic epidermal bullous necrolysis. A case of lyell-syndrome with fatal issue.
Topics: Aged; Eye; Female; Humans; Oxyphenbutazone; Skin; Stevens-Johnson Syndrome; Uveitis | 1977 |
[Toxic epidermal necrolysis in children (Lyell's syndrome). Apropos of 18 cases].
Topics: Child; Child, Preschool; Combined Modality Therapy; Critical Care; Female; Humans; Infant; Male; Oxy | 1987 |
Lymphocyte transformation test in drug-induced toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dipyrone; Drug Combinations; Female; Flurbiprofen; Hu | 1985 |
[Allergy and surgery].
Topics: Adult; Aged; Anti-Bacterial Agents; Ascorbic Acid; Drug Hypersensitivity; Erythema Multiforme; Femal | 1966 |
Adverse reaction profiles of drug eruptions.
Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Er | 1972 |
[Stevens-Johnson syndrome after treatment with Tanderil].
Topics: Adolescent; Female; Humans; Oxyphenbutazone; Stevens-Johnson Syndrome | 1968 |