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oxyphenbutazone and Rheumatism

oxyphenbutazone has been researched along with Rheumatism in 44 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Research Excerpts

ExcerptRelevanceReference
"Meclofenamic acid is an analgesic endowed with anti-inflammatory properties."1.28Clinical experiences in the treatment of pain in rheumatology. ( Pellegrini, P, 1991)
" All patients were started on 500 mg naproxen twice daily but adjustment of the dosage was permitted."1.26A compliance study in general practice of patients switched from phenylbutazone and oxyphenbutazone to naproxen and other non-steroidal anti-inflammatory drugs. ( Dickson, DJ; English, JR, 1982)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199043 (97.73)18.7374
1990's1 (2.27)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KELLY, M1
JARLOV, NV1
ROSENBAUM, ER1
SCHWARZ, GR1
LENG LEVY, J1
DAVID CHAUSSE, J1
DAVID CHAUSSE, F1
HIEMEYER, V1
SPERLING, IL1
FERREIRA, EB1
YANO, Y1
TOKIEDA, M1
GONCALVES, GW1
BOEECHAT, D1
ROBINSON, RG1
Offerhaus, L1
Magnanini, R1
Mazzoni, G1
Musiani, M1
Orlandi, V1
D'Antonio, C1
Dickson, DJ1
English, JR1
Ring, EF1
Partsch, G1
Sandtner, I1
Tausch, G1
Eberl, R1
Hoffmann, J1
Wigley, RA1
Fowles, M1
Maibach, E1
Hart, FD2
Pellegrini, P2
Colamussi, V1
Trotta, F1
Scaramelli, M1
Bazzanini, G1
Almeyda, J1
Baker, H1
Domenjoz, R1
Klinefelter, HF1
Cosh, JA1
Zicha, L1
Scheiffarth, F1
Schmid, E2
Tauber, O2
Finger, H1
Grimm-Strang, M1
Kwoczek, J1
Sell, G1
Schirmböck, J1
Widhammer, M1
Frenger, W1
Medenica, R1
Abele, I1
Dobryk, R1
Kuzmanovic, I1
Junet, R1
Boeke, F1
Lobsiger, M1
Gabel, H1
Mayr, E1
Hartl, W1
Puxeddu, A1
Heinkel, K1
Jansen, W1
Meythaler, C1
Schäffer, S1
Casademont, M1
Roimicher, S1
Azevedo, MN1
Pereira Filho, O1
France, O1
Rhein, E1
Wenig, A1
Winkler, R1
Sliwka, P1

Reviews

4 reviews available for oxyphenbutazone and Rheumatism

ArticleYear
Thermography and rheumatic diseases.
    Bibliotheca radiologica, 1975, Issue:6

    Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Body Temperature

1975
Analgesics and the stomach.
    The New Zealand medical journal, 1976, Aug-11, Volume: 84, Issue:569

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indometha

1976
Drug reactions. XII. Cutaneous reactions to anti-rheumatic drugs.
    The British journal of dermatology, 1970, Volume: 83, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Drug Eruptions; Edema; Female; Gold; Humans; Indomethacin; Lymphade

1970
[Antirheumatic drugs. 40].
    Pharmazeutische Praxis, 1969, Volume: 10

    Topics: Aminopyrine; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Antipyrine;

1969

Trials

6 trials available for oxyphenbutazone and Rheumatism

ArticleYear
[Treatment of inflammatory-degenerative rheumatic diseases with Rheumatol dragees].
    Die Medizinische Welt, 1979, Jun-08, Volume: 30, Issue:23

    Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Female; Humans; Male; Malonates; Middle Aged; Ox

1979
European experiences with tolmetin in the treatment of rheumatic diseases.
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:3

    Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Ag

1976
[Pyrasanone in the treatment of rheumatism].
    Minerva medica, 1975, Oct-10, Volume: 66, Issue:67

    Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Evaluation; Female; Gout; Huma

1975
[Double-blind clinical study with placebo versus bumadizone-Ca in 113 patients with rheumatism].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Body Tem

1973
[Therapeutic experiences with a combination of oxyphenbutazone and prednisolone in diseases of the locomotor system].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Apr-10, Volume: 62, Issue:15

    Topics: Chronic Disease; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Middle Aged; Oxy

1973
[Therapeutic and clinicopharmacological observations with oxyphenbutazone (Tanderil) and other anti-inflammatory agents of the pyrazolone group].
    Die Medizinische Welt, 1967, Jan-28, Volume: 4

    Topics: Anti-Inflammatory Agents; Humans; Oxyphenbutazone; Rheumatic Diseases; Stomach Diseases

1967

Other Studies

34 other studies available for oxyphenbutazone and Rheumatism

ArticleYear
Oxyphenbutazone ("Tanderil", G 27202): an antirheumatic derivative of phenylbutazone.
    The Medical journal of Australia, 1961, Jun-10, Volume: 48(1)

    Topics: Antirheumatic Agents; Oxyphenbutazone; Phenylbutazone; Rheumatic Diseases

1961
Tanderil (G 27202) in the treatment of the rheumatic diseases.
    Acta rheumatologica Scandinavica, 1960, Volume: 6

    Topics: Arthritis; Arthritis, Rheumatoid; Oxyphenbutazone; Phenylbutazone; Rheumatic Diseases

1960
Long-term evaluation of oxyphenbutazone in rheumatic disorders.
    Northwest medicine, 1962, Volume: 61

    Topics: Arthritis; Arthritis, Rheumatoid; Bursitis; Humans; Oxyphenbutazone; Phenylbutazone; Rheumatic Disea

1962
[CLINICAL RESULTS OF TANDERIL ADMINISTRATION IN GOUT AND RHEUMATIC PELVISPONDYLITIS].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1963, Volume: 140

    Topics: Gout; Oxyphenbutazone; Rheumatic Diseases; Spondylitis

1963
[A CONTRIBUTION TO THE ANTIPHLOGISTIC EFFECT OF TANDERIL, BUTAZOLIDINE AND DELTA-BUTAZOLIDINE].
    Medizinische Klinik, 1963, Dec-20, Volume: 58

    Topics: Arthritis; Humans; Inflammation; Lipopolysaccharides; Oxyphenbutazone; Phenylbutazone; Prednisone; R

1963
3 YEARS' EXPERIENCE WITH OXYPHENBUTAZONE IN THE TREATMENT OF RHEUMATIC DISORDERS.
    Applied therapeutics, 1964, Volume: 6

    Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Geriatrics; Gout; Osteoarthritis; Oxyphenbutazone; Pso

1964
[CLINICAL EXPERIMENTS WITH METABOLITE I OF PHENYLBUTAZONE (G 27-202) IN THE TREATMENT OF VARIOUS INFECTIOUS DISEASES AND RHEUMATIC DISEASES].
    Hospital (Rio de Janeiro, Brazil), 1963, Volume: 64

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Chemical Phenomena; Chemist

1963
[CLINICAL TRIAL OF THE PYRAZOLE DERIVATIVE TANDERIL WITH RHEUMATIC AND OTHER DISEASES].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Arthritis; Arthritis, Rheumatoid; Biomedical

1964
[SIDE-EFFECTS OF ANTI-INFLAMMATORY DRUGS USED IN RHEUMATOLOGY].
    Hospital (Rio de Janeiro, Brazil), 1964, Volume: 66

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Aspirin; Drug Therapy; Oxyphenbuta

1964
[OXYPHENYLBUTAZONE IN GYNECOLOGY].
    Hospital (Rio de Janeiro, Brazil), 1964, Volume: 66

    Topics: Bursitis; Cholecystitis; Endometritis; Female; Genital Diseases, Female; Gynecology; Humans; Joint D

1964
Oxyphenbutazone ("Tanderil") in rheumatic disease.
    The Medical journal of Australia, 1962, Jul-14, Volume: 49(2)

    Topics: Oxyphenbutazone; Phenylbutazone; Rheumatic Diseases

1962
[Russian roulette with pyrazolones].
    Nederlands tijdschrift voor geneeskunde, 1983, Apr-09, Volume: 127, Issue:15

    Topics: Agranulocytosis; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Female; Humans; Mal

1983
[Clinical control of the therapeutic action of a decontracting, anti-rheumatic, analgesic drug combination for topical use, in comparison with oxyphenbutazone].
    La Clinica terapeutica, 1982, Apr-30, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Combinations; Fema

1982
A compliance study in general practice of patients switched from phenylbutazone and oxyphenbutazone to naproxen and other non-steroidal anti-inflammatory drugs.
    Current medical research and opinion, 1982, Volume: 8, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Drug Therapy, Combination; Female; Humans; Male; Middle Aged;

1982
In vitro investigations on the influence of antirheumatic drugs on purine phosphoribosyltransferases and their possible clinical consequence.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Adenine Phosphoribosyltransferase; Apazone; Cell-Free System; Erythrocytes; Flufenamic Acid; Humans;

1977
Inflammatory disease and its control in rheumatic disorders.
    British medical journal, 1975, Oct-25, Volume: 4, Issue:5990

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Female; Gout; Hum

1975
Clinical experiences in the treatment of pain in rheumatology.
    The Clinical journal of pain, 1991, Volume: 7 Suppl 1

    Topics: Adult; Aged; Diclofenac; Female; Humans; Indomethacin; Male; Meclofenamic Acid; Middle Aged; Oxyphen

1991
[Pharmacology of antirheumatic drugs].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1969, Volume: 1

    Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Central Nervous System; Chemi

1969
Primary fibrositis and its treatment with the pyrazolone derivatives, butazolidin and tandearil.
    The Johns Hopkins medical journal, 1972, Volume: 130, Issue:5

    Topics: Adult; Age Factors; Diagnosis, Differential; Drug Eruptions; Edema; Female; Fibromyalgia; Humans; Ma

1972
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974
[Clinical and experimental studies on phenylbutazone and oxyphenbutazone].
    Arzneimittel-Forschung, 1965, Volume: 15, Issue:8

    Topics: Acetylcholine; Animals; Asthma; Gastric Juice; Guinea Pigs; Histamine H1 Antagonists; Humans; Oxyphe

1965
Analgesics and non-steroid anti-inflammatory agents in rheumatic disease.
    The Practitioner, 1972, Volume: 208, Issue:243

    Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bone Neoplasms; Gout; Humans;

1972
[Studies on the tolerance of Realin in rheumatic diseases].
    Medizinische Monatsschrift, 1972, Volume: 26, Issue:4

    Topics: Adult; Drug Combinations; Drug Tolerance; Female; Humans; Male; Middle Aged; Oxyphenbutazone; Predni

1972
[Which orthopedic indications are promising a successful therapy using Realin?].
    Zeitschrift fur Allgemeinmedizin, 1972, Apr-20, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Oxyphenbutazone;

1972
[Local oxyphenbutazone therapy in blunt injuries and rheumatic diseases].
    Zeitschrift fur Allgemeinmedizin, 1972, May-10, Volume: 48, Issue:13

    Topics: Humans; Oxyphenbutazone; Rheumatic Diseases; Wounds and Injuries

1972
[Efficacy and compatibility of bumadizone-Ca in rheumatoid diseases. A comparison with oxyphenbutazone].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Dose-Response Relationshi

1973
[Letter: Scleritis].
    Deutsche medizinische Wochenschrift (1946), 1974, Volume: 99, Issue:18

    Topics: Adrenal Cortex Hormones; Eye Diseases; Female; Humans; Oxyphenbutazone; Rheumatic Diseases; Sclera

1974
[On the problem of specificity of drug-allergic immune reactions by aminophenazone-containing antirheumatic aents].
    Klinische Wochenschrift, 1966, Jan-01, Volume: 44, Issue:1

    Topics: Aminopyrine; Animals; Antigen-Antibody Reactions; Antipyrine; Complement Fixation Tests; Drug Hypers

1966
[Oxyphenylbutazone rheumatologic practice].
    Revista espanola de reumatismo y enfermedades osteoarticulares, 1966, Volume: 11, Issue:8

    Topics: Humans; Joint Diseases; Oxyphenbutazone; Rheumatic Diseases

1966
[Use of oxyphenylbutazone in rheumatic diseases].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:7

    Topics: Adult; Aged; Capsules; Female; Humans; Male; Middle Aged; Oxyphenbutazone; Rheumatic Diseases; Suppo

1968
[Combination of ketophenylbutazone (Ketason), oxyphenbutazone and proteolytic enzymes in rheumatic diseases].
    Revista medica de Chile, 1968, Volume: 96, Issue:8

    Topics: Administration, Oral; Arthritis; Capsules; Drug Synergism; Humans; Oxyphenbutazone; Peptide Hydrolas

1968
[Clinical experiences in the treatment of rheumatic and non-rheumatic infectious diseases with an antiphlogistic agents].
    Zeitschrift fur Allgemeinmedizin, 1970, Oct-20, Volume: 46, Issue:29

    Topics: Anti-Bacterial Agents; Humans; Infections; Inflammation; Oxyphenbutazone; Rheumatic Diseases

1970
[Treatment of rheumatic diseases with a new combination preparation (Realin)].
    Therapie der Gegenwart, 1970, Volume: 109, Issue:9

    Topics: Adult; Female; Humans; Male; Oxyphenbutazone; Prednisolone; Rheumatic Diseases

1970
[Acute treatment of selected rheumatic diseases with oxyphenbutazone and prednisolone].
    Die Medizinische Welt, 1971, Nov-13, Volume: 46

    Topics: Adolescent; Adult; Aged; Drug Synergism; Female; Humans; Male; Middle Aged; Oxyphenbutazone; Prednis

1971