oxyphenbutazone has been researched along with Pulmonary Fibrosis in 5 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roswit, B | 1 |
| White, DC | 1 |
| James, DG | 2 |
| Carstairs, LS | 2 |
| Trowell, J | 1 |
| Sharma, OP | 2 |
| Klein, U | 2 |
| Müller-Fassbender, H | 2 |
| Bublath, H | 1 |
| Heinze, HG | 2 |
| Bablath, H | 1 |
| Siltzbach, LE | 1 |
1 review available for oxyphenbutazone and Pulmonary Fibrosis
| Article | Year |
|---|---|
Severe radiation injuries of the lung.
Topics: Adrenal Cortex Hormones; Aged; Bed Rest; Cobalt Radioisotopes; Dexamethasone Isonicotinate; Female; | 1977 |
3 trials available for oxyphenbutazone and Pulmonary Fibrosis
| Article | Year |
|---|---|
Treatment of sarcoidosis. Report of a controlled therapeutic trial.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Lung Diseases; Male; Middle Aged; | 1967 |
[Effects of oxyphenbutazone on radiation pneumonitis or radiation fibrosis following irradiation for breast carcinoma].
Topics: Breast Neoplasms; Clinical Trials as Topic; Cobalt Isotopes; Female; Humans; Lung; Oxyphenbutazone; | 1972 |
[Effect of oxyphenbutazone on radiation-induced lung diseases].
Topics: Adult; Aged; Breast Neoplasms; Bronchography; Female; Humans; Lung Diseases; Middle Aged; Oxyphenbut | 1973 |
1 other study available for oxyphenbutazone and Pulmonary Fibrosis
| Article | Year |
|---|---|
A tale of two cities: a comparison of sarcoidosis in London and New York.
Topics: Adult; Age Factors; Black People; Chloroquine; Diagnosis, Differential; Eye Manifestations; Female; | 1969 |