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oxyphenbutazone and Polymyalgia Rheumatica

oxyphenbutazone has been researched along with Polymyalgia Rheumatica in 4 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Polymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hart, FD1
Wadman, B1
Werner, I1
Cosh, JA1
Widhammer, M1
Frenger, W1

Other Studies

4 other studies available for oxyphenbutazone and Polymyalgia Rheumatica

ArticleYear
Inflammatory disease and its control in rheumatic disorders.
    British medical journal, 1975, Oct-25, Volume: 4, Issue:5990

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Female; Gout; Hum

1975
Therapeutic hazards of phenylbutazone and oxyphenbutazone in polymyalgia rheumatica.
    Lancet (London, England), 1967, Mar-18, Volume: 1, Issue:7490

    Topics: Aged; Female; Giant Cell Arteritis; Humans; Male; Middle Aged; Oxyphenbutazone; Phenylbutazone; Poly

1967
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974
[Efficacy and compatibility of bumadizone-Ca in rheumatoid diseases. A comparison with oxyphenbutazone].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Dose-Response Relationshi

1973