oxyphenbutazone has been researched along with Pain in 29 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind randomized trial was carried out in 31 patients suffering from acute, minor ligamentous injuries to compare the efficacy of diflunisal in the relief of pain with that of oxyphenbutazone." | 5.04 | Diflunisal in the management of sprains. ( Adams, ID, 1978) |
| "Meclofenamic acid is an analgesic endowed with anti-inflammatory properties." | 1.28 | Clinical experiences in the treatment of pain in rheumatology. ( Pellegrini, P, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (96.55) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEIN, ID | 1 |
| BARNES, WC | 1 |
| MALAMENT, M | 1 |
| GUZMAN, F | 1 |
| BRAUN, C | 1 |
| LIM, RK | 1 |
| POTTER, GD | 1 |
| RODGERS, DW | 1 |
| BOEECHAT, D | 1 |
| Corrigan, AB | 1 |
| Commandré, FA | 1 |
| Fornaris, E | 1 |
| Fourré, JM | 1 |
| Raybaud, A | 1 |
| Colonna, P | 1 |
| Pirdas, C | 1 |
| Watson, PG | 2 |
| Archer, DS | 1 |
| Fowler, PD | 1 |
| Adams, ID | 1 |
| Dieckmann, J | 1 |
| Mazurkiewicz, H | 1 |
| Stachurski, W | 1 |
| Adamowski, R | 1 |
| Pandhi, RK | 1 |
| Dedi, TR | 1 |
| Pellegrini, P | 1 |
| Carty, MJ | 1 |
| Hart, FD | 1 |
| Widhammer, M | 1 |
| Frenger, W | 1 |
| Medenica, R | 1 |
| Abele, I | 1 |
| Dobryk, R | 1 |
| Kuzmanovic, I | 1 |
| Junet, R | 1 |
| Seghezzi, R | 1 |
| Borri, P | 1 |
| Chierichetti, S | 1 |
| Ferrari, P | 1 |
| Mikkelsen, OA | 1 |
| Mäder, H | 1 |
| McKay, DA | 1 |
| Clemett, RS | 1 |
| Wilkinson, P | 1 |
| Pilliaert, JM | 1 |
| Golding, D | 1 |
| Naess, K | 1 |
| Sugano, T | 1 |
| Fujimori, I | 1 |
| Grimmeisen, H | 1 |
| Vandehove, P | 1 |
| Vande Weghe, JP | 1 |
| Boedts, D | 1 |
| Marmor, L | 1 |
| Peter, JB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Single-dose, Pharmacokinetic Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Orthodontic Pain[NCT05844995] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | ||
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for oxyphenbutazone and Pain
| Article | Year |
|---|---|
[Comparative double-blind study of Bi-Profenid and oxyphenbutazone in sports pathology].
Topics: Adolescent; Adult; Ankle Injuries; Athletic Injuries; Clinical Trials as Topic; Double-Blind Method; | 1983 |
Comparison of oxyphenbutazone and placebo in the treatment of superficial thrombophelbitis: an object lesson in clinical trial design.
Topics: Clinical Trials as Topic; Double-Blind Method; Erythema; Female; Humans; Male; Middle Aged; Oxyphenb | 1977 |
Diflunisal in the management of sprains.
Topics: Adolescent; Adult; Age Factors; Aged; Analgesics; Biphenyl Compounds; Clinical Trials as Topic; Fema | 1978 |
[Possibilities for pain reduction by the prevention of edemas and elimination of endogenous pain producing substances].
Topics: Apicoectomy; Coumarins; Drug Combinations; Edema; Humans; Hydroxyethylrutoside; Maxillary Sinus; Noc | 1978 |
The use of oxyphenbutazone ('Tanderil') in acute pelvic inflammatory disease.
Topics: Female; Follow-Up Studies; Gonorrhea; Humans; Kenya; Length of Stay; Male; Neisseria gonorrhoeae; Ox | 1973 |
[Double-blind clinical study with placebo versus bumadizone-Ca in 113 patients with rheumatism].
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Body Tem | 1973 |
[Controlled clinical trial of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370) and oxyphenbutazone in thrombophlebitis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Blood Cell Count; Blood Urea Nitrogen; Clinical Trials as Top | 1972 |
Tanderil in surgery of rheumatic diseases. A double blind trial at dorsal synovectomy of the wrist joint.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Edema; Female; Huma | 1972 |
[Comparative studies on the effect of bromelin and oxyphenbutazone in episiotomy pains].
Topics: Bromelains; Clinical Trials as Topic; Episiotomy; Female; Humans; Oxyphenbutazone; Pain | 1973 |
Treatment of episcleritis. A double-blind trial comparing betamethasone 0.1 per cent, oxyphenbutazone 10 per cent, and placebo eye ointments.
Topics: Administration, Topical; Adolescent; Adult; Betamethasone; Clinical Trials as Topic; Cornea; Eye Dis | 1973 |
19 other studies available for oxyphenbutazone and Pain
| Article | Year |
|---|---|
The effect of oxyphenbutazone on pain related to vascular disease.
Topics: Oxyphenbutazone; Pain; Phenylbutazone; Vascular Diseases | 1960 |
OSTEITIS PUBIS.
Topics: Geriatrics; Humans; Male; Osteitis; Oxyphenbutazone; Pain; Phenylbutazone; Postoperative Complicatio | 1963 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
[OXYPHENYLBUTAZONE IN GYNECOLOGY].
Topics: Bursitis; Cholecystitis; Endometritis; Female; Genital Diseases, Female; Gynecology; Humans; Joint D | 1964 |
Rehabilitation of injured football players.
Topics: Adult; Bone and Bones; Humans; Joints; Muscles; Oxyphenbutazone; Pain; Physical Therapy Modalities; | 1967 |
The diagnosis and management of scleritis.
Topics: Eye Diseases; Humans; Indomethacin; Inflammation; Necrosis; Oxyphenbutazone; Pain; Sclera | 1980 |
[Effect of Tanderil in orthopedic diseases].
Topics: Adult; Aged; Bone Neoplasms; Drug Tolerance; Female; Humans; Inflammation; Male; Middle Aged; Osteom | 1977 |
Letter: Fixed skin eruption caused by oxyphenbutazone with cross-reactivity to phenylbutazone.
Topics: Adult; Drug Interactions; Humans; Male; Oxyphenbutazone; Pain; Phenylbutazone; Skin Diseases | 1975 |
Clinical experiences in the treatment of pain in rheumatology.
Topics: Adult; Aged; Diclofenac; Female; Humans; Indomethacin; Male; Meclofenamic Acid; Middle Aged; Oxyphen | 1991 |
Pain in haemophilia.
Topics: Acetaminophen; Analgesics; Hemophilia A; Humans; Indomethacin; Male; Meperidine; Oxyphenbutazone; Pa | 1973 |
Pain in osteoarthrosis.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Cartilage Diseases; Exercise Therapy; Hip; Humans; Im | 1974 |
[Efficacy and compatibility of bumadizone-Ca in rheumatoid diseases. A comparison with oxyphenbutazone].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Dose-Response Relationshi | 1973 |
[Tanderil in ORL surgery. Apropos of 63 cases].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Edema; Female; Fever; Humans; Male; Middle Aged; O | 1973 |
Treating erythema nodosum.
Topics: Adult; Erythema Nodosum; Female; Humans; Oxyphenbutazone; Pain; Sarcoidosis | 1969 |
[Anticoagulants--antiphlogistics--acetylsalicylic acid. A note on interaction].
Topics: Analgesics; Angina Pectoris; Anticoagulants; Drug Synergism; Ecchymosis; Female; Humans; Middle Aged | 1970 |
[Clinical aspecs of the anti-inflammatory drugs in the surgical and orthopedic fields].
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis; Gout; Humans; Indomethacin; Joint Diseases; Mefenam | 1970 |
[Experiences with a combination of oxyphenbutazone and prednisolone in painful diseases of the locomotor system].
Topics: Humans; Joint Diseases; Oxyphenbutazone; Pain; Prednisolone | 1970 |
Observations on the use of benzydamine hydrochloride in otorhinolaryngology.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Chronic Disease; Cicatrix; Deglutition Disorders; | 1968 |
Osteoarthritis of the carpometacarpal joint of the thumb.
Topics: Anti-Inflammatory Agents; Arthrodesis; Arthroplasty; Female; Humans; Injections, Intra-Articular; Li | 1969 |