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oxyphenbutazone and Pain, Postoperative

oxyphenbutazone has been researched along with Pain, Postoperative in 10 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"A double-blind controlled trial was carried out to test the value of oxyphenbutazone (Tandearil; Geigy Pharmaceuticals) in preventing the troublesome edema of external genitalia that may occasionally develop after bilateral inguinal herniorrhaphy."7.64Trial of oxyphenbutazone for postoperative edema after bilateral herniorrhaphy. ( ILES, JD, 1963)
"The efficacy of oxyphenbutazone (OPB) in the control of postoperative inflammation was investigated, and previous findings were extended on the rate at which the inflammatory response of plasma seromucoids was significantly modified by this drug."7.64Effects of oxyphenbutazone (tandearil) on plasma seromucoids. II. In postoperative inflammation. ( BARCELO, R; LEBLANC, C; LEGRESLEY, LP; RIOPEL, P, 1963)
"A double-blind controlled trial was carried out to test the value of oxyphenbutazone (Tandearil; Geigy Pharmaceuticals) in preventing the troublesome edema of external genitalia that may occasionally develop after bilateral inguinal herniorrhaphy."3.64Trial of oxyphenbutazone for postoperative edema after bilateral herniorrhaphy. ( ILES, JD, 1963)
"The efficacy of oxyphenbutazone (OPB) in the control of postoperative inflammation was investigated, and previous findings were extended on the rate at which the inflammatory response of plasma seromucoids was significantly modified by this drug."3.64Effects of oxyphenbutazone (tandearil) on plasma seromucoids. II. In postoperative inflammation. ( BARCELO, R; LEBLANC, C; LEGRESLEY, LP; RIOPEL, P, 1963)
"There was a significant reduction of postoperative pain and trismus with Rheumapax in addition to a favorable, through nonsignificant, effect on swelling."2.64Clinical and hematological investigation of Rheumapax in surgical removal of impacted wisdom teeth from the mandible. ( Bystedt, H, 1976)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ILES, JD1
BARCELO, R1
LEBLANC, C1
RIOPEL, P1
LEGRESLEY, LP1
Tamura, T1
Kvarnes, L1
Detournay, M1
Svendsen, H1
Honig, WJ1
Bystedt, H1
Breytenbach, HS1

Reviews

1 review available for oxyphenbutazone and Pain, Postoperative

ArticleYear
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1983, Volume: 38, Issue:7

    Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indometha

1983

Trials

4 trials available for oxyphenbutazone and Pain, Postoperative

ArticleYear
Naproxen suppositories in postoperative pain and swelling after joint surgery. A comparative, double-blind study.
    Scandinavian journal of rheumatology, 1984, Volume: 13, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Elbow Joint; Female; Finger Joint; Humans; Joi

1984
[The effect of naproxen suppositories on postoperative pain and edema compared with oxyphenbutazone and placebo. A single blind pilot project in rheumatoid surgery].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1982, Jan-20, Volume: 102, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Edema; Humans; Joints; Male; Middle Aged; Naproxen; Oxyphenbu

1982
The use of diflunisal in post-operative pain: a report of double-blind comparative trials in patients after meniscectomy.
    Current medical research and opinion, 1978, Volume: 5, Issue:7

    Topics: Adolescent; Adult; Analgesics; Aspirin; Biphenyl Compounds; Clinical Trials as Topic; Double-Blind M

1978
Clinical and hematological investigation of Rheumapax in surgical removal of impacted wisdom teeth from the mandible.
    International journal of oral surgery, 1976, Volume: 5, Issue:2

    Topics: Adult; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dr

1976

Other Studies

5 other studies available for oxyphenbutazone and Pain, Postoperative

ArticleYear
Trial of oxyphenbutazone for postoperative edema after bilateral herniorrhaphy.
    Canadian Medical Association journal, 1963, Apr-20, Volume: 88

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Double-Blind Method; Edema; Hernia, Inguinal; He

1963
Effects of oxyphenbutazone (tandearil) on plasma seromucoids. II. In postoperative inflammation.
    Canadian Medical Association journal, 1963, Mar-23, Volume: 88

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Proteins; Double-Blind Method; Fe

1963
[Clofezone and oxyphenbutazone excluded from dental use].
    Nihon Shika Ishikai zasshi, 1984, Volume: 37, Issue:4

    Topics: Anti-Inflammatory Agents; Humans; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone; Temporomandi

1984
[Fenoprofen as a treatment of postsurgical pain].
    Revue medicale de Liege, 1983, Nov-15, Volume: 38, Issue:22

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fenoprofen; Humans; Male; Oxyphenbutazone; P

1983
Effects of tanderil (oxyphenbutazone), chymoral (proteolytic enzymes) and placebo in the control of swelling, trismus and pain after the removal of impacted wisdom teeth.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1976, Volume: 31, Issue:2

    Topics: Female; Humans; Male; Molar; Oxyphenbutazone; Pain, Postoperative; Peptide Hydrolases; Placebos; Pos

1976