oxyphenbutazone has been researched along with Osteoarthritis in 21 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Postoperative use of special elastic bandages and oxyphenbutazone significantly decreased the frequency of thrombosis." | 5.05 | Survey of orthopaedic surgical research in a university center (Linköping). ( Lindahl, O, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ONEL, D | 1 |
| IMRE, I | 1 |
| GJORUP, L | 1 |
| HART, FD | 4 |
| SPERLING, IL | 2 |
| BOARDMAN, PL | 1 |
| CASTAGNA, AN | 1 |
| Lindahl, O | 1 |
| Fowler, PD | 1 |
| Faragher, EB | 1 |
| Maibach, E | 1 |
| Roux, H | 1 |
| Cosh, JA | 1 |
| Medenica, R | 1 |
| Abele, I | 1 |
| Dobryk, R | 1 |
| Kuzmanovic, I | 1 |
| Junet, R | 1 |
| Erdmann, GH | 1 |
| El-Mehairy, MM | 1 |
| Shaker, A | 1 |
| Bahgat, NE | 1 |
| Hamza, S | 1 |
| Salam, MS | 1 |
| Alvarez Fernández, V | 1 |
| Tagiaferro, E | 1 |
| Marmor, L | 1 |
| Peter, JB | 1 |
5 trials available for oxyphenbutazone and Osteoarthritis
| Article | Year |
|---|---|
Survey of orthopaedic surgical research in a university center (Linköping).
Topics: Arthroscopy; Back Pain; Bandages; Clinical Trials as Topic; Colles' Fracture; Fractures, Ununited; H | 1984 |
European experiences with tolmetin in the treatment of rheumatic diseases.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Ag | 1976 |
[Double-blind clinical study with placebo versus bumadizone-Ca in 113 patients with rheumatism].
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Body Tem | 1973 |
Oxyphenbutazone and flufenamic acid in the treatment of osteo-arthritis of the knee. A double-blind trial comparison.
Topics: Clinical Trials as Topic; Flufenamic Acid; Humans; Knee; Osteoarthritis; Oxyphenbutazone | 1974 |
A double-blind comparison of niflumic acid with phenylbutazone, oxyphenylbutazone and placebo in the treatment of osteoarthrosis.
Topics: Aniline Compounds; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Evaluation; Female; Hip; | 1974 |
16 other studies available for oxyphenbutazone and Osteoarthritis
| Article | Year |
|---|---|
[On Tanderil and the results of its clinical use].
Topics: Arthritis, Rheumatoid; Humans; Joint Diseases; Osteoarthritis; Oxyphenbutazone; Phenylbutazone; Spon | 1962 |
[Medicinal treatment of arthroses. Effects of oxyphenbutazone (Tanderil) compared with phenylbutazone (Butazolidin)].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Humans; Joint Diseases; Osteoarthritis; Oxyphenb | 1963 |
DEGENERATIVE JOINT DISEASES--DISCS AND OSTEOARTHRITIS. II. DIAGNOSIS AND MANAGEMENT OF OSTEOARTHRITIS.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Diagnosis, Differential; | 1963 |
ACUTE CONFUSION COINCIDING WITH TREATMENT WITH HYDROXYPHENYLBUTAZONE (TANDERIL).
Topics: Confusion; Hallucinations; Mental Disorders; Osteoarthritis; Oxyphenbutazone; Psychoses, Substance-I | 1963 |
3 YEARS' EXPERIENCE WITH OXYPHENBUTAZONE IN THE TREATMENT OF RHEUMATIC DISORDERS.
Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Geriatrics; Gout; Osteoarthritis; Oxyphenbutazone; Pso | 1964 |
TRIAL OF NIFENAZONE ("THYLIN").
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Arthritis; Arthritis, Rheumatoid; Ni | 1964 |
[CONTRIBUTION TO THE STUDY OF INFLAMMATORY DISEASES OF THE LOCOMOTOR APPARATUS].
Topics: Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Fibromyalgia; Humans; Opipram | 1964 |
Drug and non-drug factors influencing adverse reaction to pyrazoles.
Topics: Adult; Aged; Anemia; Arthritis, Rheumatoid; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; | 1977 |
Adverse reactions with long-term use of phenylbutazone and oxyphenbutazone.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Digestive System; Edema; Female; Fibromyalgia | 1969 |
[Therapeutic trail of tanderil in rheumatology].
Topics: Adult; Aged; Arthritis; Back Pain; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis; Ox | 1967 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
Pain in osteoarthrosis.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Cartilage Diseases; Exercise Therapy; Hip; Humans; Im | 1974 |
Analgesics and non-steroid anti-inflammatory agents in rheumatic disease.
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bone Neoplasms; Gout; Humans; | 1972 |
[The Tanderil + prednisolone combination in osteoarthritis: its efficacy and tolerance].
Topics: Drug Combinations; Female; Humans; Male; Osteoarthritis; Oxyphenbutazone; Prednisolone | 1972 |
[Clinical studies of a new antirheumatic-analgesic drug combination].
Topics: Adolescent; Adult; Aged; Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumat | 1972 |
Osteoarthritis of the carpometacarpal joint of the thumb.
Topics: Anti-Inflammatory Agents; Arthrodesis; Arthroplasty; Female; Humans; Injections, Intra-Articular; Li | 1969 |