oxyphenbutazone has been researched along with Neoplasms in 11 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Zhao, Y | 1 |
| Guan, YY | 1 |
| Zhao, F | 1 |
| Yu, T | 1 |
| Zhang, SJ | 1 |
| Zhang, YZ | 1 |
| Duan, YC | 1 |
| Zhou, XL | 1 |
| COCCHI, U | 1 |
| PELUSO, E | 1 |
| NUNEZCABEZAS, A | 1 |
| MARTINEZSAHUQUILLO, A | 1 |
| PAUWEN, J | 1 |
| Frenger, W | 1 |
| Cheikh-Ali, H | 1 |
| Miotti, R | 1 |
| Kleibel, F | 1 |
3 reviews available for oxyphenbutazone and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Recent strategies targeting Embryonic Ectoderm Development (EED) for cancer therapy: Allosteric inhibitors, PPI inhibitors, and PROTACs.
Topics: Ectoderm; Enhancer of Zeste Homolog 2 Protein; Humans; Intercellular Signaling Peptides and Proteins | 2022 |
2 trials available for oxyphenbutazone and Neoplasms
| Article | Year |
|---|---|
[Study of the effect of oxyphenbutazone on the radiation reaction in cobalt isotope teletherapy of neoplasms in a double blind experiment].
Topics: Clinical Trials as Topic; Cobalt Isotopes; Deglutition Disorders; Esophageal Neoplasms; Humans; Neop | 1969 |
[Double blind experiment with vasoactive drugs in radiogenic hypotension].
Topics: Humans; Hypotension; Hypotension, Orthostatic; Male; Middle Aged; Neoplasms; Norepinephrine; Oxyphen | 1969 |
6 other studies available for oxyphenbutazone and Neoplasms
| Article | Year |
|---|---|
[Preliminary report on experiences with oxyphenbutazone (Tanderil) in roentgen-irradiated patients with tumors of the mouth, pharynx and larynx].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Humans; Laryngeal Neoplasms; Larynx; Mouth Neopl | 1963 |
[THERAPEUTIC EFFECTS OF A METABOLITE OF PHENYLBUTAZONE (G 27202) IN PRIMARY SEROSITIS].
Topics: Aminopyrine; Blood Sedimentation; Humans; Isoniazid; Neoplasms; Oxyphenbutazone; Peritonitis; Perito | 1964 |
[INDICATIONS FOR OXYPHENBUTAZONE IN PLASTIC SURGERY].
Topics: Burns; Edema; Humans; Inflammation; Neoplasms; Nose; Oxyphenbutazone; Postoperative Complications; S | 1964 |
[OXYPHENBUTAZONE IN THE RADIOTHERAPY OF UTERINE CARCINOMA].
Topics: Anti-Inflammatory Agents; Drug Therapy; Female; Humans; Neoplasms; Oxyphenbutazone; Uterine Neoplasm | 1964 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
[Studies on the problem of the modification of human isoagglutinins with adrenal cortex steroids, x-rays and anti-inflammatory agents].
Topics: Adrenal Cortex Hormones; Drug Therapy; Hemagglutination Tests; Humans; Isoantibodies; Neoplasms; Oxy | 1967 |