Page last updated: 2024-11-02

oxyphenbutazone and Liver Cirrhosis

oxyphenbutazone has been researched along with Liver Cirrhosis in 2 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pentikäinen, LA1
Mustala, OO1
Hvidberg, EF1
Andreasen, PB1
Ranek, L1

Other Studies

2 other studies available for oxyphenbutazone and Liver Cirrhosis

ArticleYear
Effect of oxyphenbutazone on liver function in man.
    Annals of clinical research, 1972, Volume: 4, Issue:5

    Topics: Administration, Oral; Aged; Bilirubin; Depression, Chemical; Humans; Liver; Liver Cirrhosis; Liver F

1972
Plasma half-life of phenylbutazone in patients with impaired liver function.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:2

    Topics: Adult; Aged; Female; Galactose; Half-Life; Humans; Liver Cirrhosis; Liver Function Tests; Male; Midd

1974