Page last updated: 2024-11-02

oxyphenbutazone and Granulomas

oxyphenbutazone has been researched along with Granulomas in 10 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Research Excerpts

ExcerptRelevanceReference
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."7.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."3.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dhermy, P1
Prevost-Boure, F1
Guimaraes, M1
Merad, B1
Andersson, DE1
Langworth, S1
Newman, HC1
Ost, A1
Ishak, KG1
Kirchner, JP1
Dhar, JK1
Tariq, M1
Ageel, AM1
al-Yahya, MA1
Mossa, JS1
al-Said, MS1
Deshmukh, VK1
Raman, PH1
Dhuley, JN1
Naik, SR1
Mörsdorf, K1
Anspach, K1
Riedel, R1
Schoetensack, W1
Nakanishi, M1
Imamura, H1
Maruyama, Y1
Ikeda, T1
Watanabe, S1
Hayakawa, M1
Yamamoto, H1
Saito, C1
Okamoto, T1
Awata, H1
Inukai, T1
Hirohashi, A1
Yukawa, Y1

Other Studies

10 other studies available for oxyphenbutazone and Granulomas

ArticleYear
[A case of deep annular granuloma of the eyelid].
    Journal francais d'ophtalmologie, 1983, Volume: 6, Issue:1

    Topics: Adult; Diagnosis, Differential; Eyelid Diseases; Female; Granuloma; Humans; Oxyphenbutazone

1983
Reversible bone marrow granulomas-adverse effect of oxyphenbutazone therapy.
    Acta medica Scandinavica, 1980, Volume: 207, Issue:1-2

    Topics: Bone Marrow; Bone Marrow Diseases; Female; Granuloma; Humans; Middle Aged; Oxyphenbutazone

1980
Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:7

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Diazepam; Granuloma; Hu

1977
Anti-inflammatory activity of Teucrium polium.
    International journal of tissue reactions, 1989, Volume: 11, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Granuloma; Oxyphenbutazone; Plant Extracts; Rats;

1989
Role of ceruloplasmin in inflammation: increased serum ceruloplasmin levels during inflammatory conditions and its possible relationship with anti-inflammatory agents.
    Pharmacological research communications, 1985, Volume: 17, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Ceruloplasmin; Edema; Granu

1985
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr

1973
Pharmacological investigations of 2-amino-3-ethoxy-carbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Bradykinin; C

1970
[Granuloma faciale as an entity localized in the face--typical cases, cases affecting the limbs and the therapeutic effects of tanderil].
    Acta dermatologica-Kyoto. English edition, 1968, Volume: 63, Issue:2

    Topics: Arm; Diagnosis, Differential; Erythema; Facial Dermatoses; Female; Granuloma; Humans; Leg Dermatoses

1968
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:6

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car

1969