Page last updated: 2024-11-02

oxyphenbutazone and Goiter

oxyphenbutazone has been researched along with Goiter in 3 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).

Research Excerpts

ExcerptRelevanceReference
"A woman who had taken oxyphenbutazone for 4 years because of back pain presented with goitre and hypothyroidism."3.65Oxyphenbutazone-induced goitre. ( Clark, F; Lane, RJ; McCollum, JK, 1977)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lane, RJ1
Clark, F1
McCollum, JK1
Norell, E2

Other Studies

3 other studies available for oxyphenbutazone and Goiter

ArticleYear
Oxyphenbutazone-induced goitre.
    Postgraduate medical journal, 1977, Volume: 53, Issue:616

    Topics: Back Pain; Female; Goiter; Humans; Hypothyroidism; Middle Aged; Oxyphenbutazone

1977
[Can treatment with tandearil cause struma?].
    Svensk tandlakare tidskrift. Swedish dental journal, 1967, Volume: 60, Issue:10

    Topics: Goiter; Oxyphenbutazone

1967
[Can Tanderil therapy induce struma?].
    Lakartidningen, 1967, Sep-06, Volume: 64, Issue:36

    Topics: Goiter; Humans; Male; Middle Aged; Oxyphenbutazone

1967