oxyphenbutazone has been researched along with Goiter in 3 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Excerpt | Relevance | Reference |
---|---|---|
"A woman who had taken oxyphenbutazone for 4 years because of back pain presented with goitre and hypothyroidism." | 3.65 | Oxyphenbutazone-induced goitre. ( Clark, F; Lane, RJ; McCollum, JK, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lane, RJ | 1 |
Clark, F | 1 |
McCollum, JK | 1 |
Norell, E | 2 |
3 other studies available for oxyphenbutazone and Goiter
Article | Year |
---|---|
Oxyphenbutazone-induced goitre.
Topics: Back Pain; Female; Goiter; Humans; Hypothyroidism; Middle Aged; Oxyphenbutazone | 1977 |
[Can treatment with tandearil cause struma?].
Topics: Goiter; Oxyphenbutazone | 1967 |
[Can Tanderil therapy induce struma?].
Topics: Goiter; Humans; Male; Middle Aged; Oxyphenbutazone | 1967 |