oxyphenbutazone has been researched along with Gastric Ulcer in 14 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effect of the angiotensin converting enzyme inhibitor, captopril, on two models of gastric ulcers; oxyphenbutazone and ethanol-induced lesions." | 3.68 | Effect of captopril on oxyphenbutazone and ethanol-induced gastric lesions in rats. ( Bhounsule, SA; Diniz D'Souza, RS; Hede, SS; Pereira, JS, 1990) |
| "We have compared the effect of the converting enzyme inhibitors, captopril and enalapril, on two models of gastric ulcers, viz; ethanol and oxyphenbutazone-induced lesions in rats." | 3.68 | Comparison of the effects of captopril and enalapril on oxyphenbutazone and ethanol-induced gastric lesions in rats. ( Bhounsule, SA; D'Souza, RS; Dhume, VG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DENKO, CW | 1 |
| LIBRO, V | 1 |
| NICOD, JL | 1 |
| Varma, DR | 1 |
| Wigley, RA | 1 |
| Fowles, M | 1 |
| Ancill, RJ | 1 |
| Bhounsule, SA | 2 |
| Pereira, JS | 1 |
| Hede, SS | 1 |
| Diniz D'Souza, RS | 1 |
| D'Souza, RS | 1 |
| Dhume, VG | 1 |
| Cosh, JA | 1 |
| Wilhelmi, G | 1 |
| Bhargava, KP | 1 |
| Gupta, MB | 1 |
| Tangri, KK | 1 |
| Kuschinsky, G | 1 |
| Takashima, T | 1 |
| Kado, Y | 1 |
| Kumada, S | 1 |
| Måseide, T | 1 |
1 review available for oxyphenbutazone and Gastric Ulcer
| Article | Year |
|---|---|
Analgesics and the stomach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indometha | 1976 |
13 other studies available for oxyphenbutazone and Gastric Ulcer
| Article | Year |
|---|---|
THE EFFECT OF PHENYLBUTAZONE AND ITS DERIVATIVES OXYPHENBUTAZONE AND SULFINPYRAZONE ON S-35-SULFATE INCORPORATION IN CARTILAGE AND STOMACH.
Topics: Cartilage; Hypophysectomy; Metabolism; Oxyphenbutazone; Pharmacology; Phenylbutazone; Rats; Research | 1964 |
[FINDINGS ON GASTRIC MODIFICATIONS INDUCED BY PYRAZOLIDINIC DERIVATIVES].
Topics: Gastric Mucosa; Oxyphenbutazone; Phenylbutazone; Rats; Research; Stomach Ulcer; Toxicology | 1964 |
[STOMACH ULCERS DUE TO DRUGS].
Topics: Adrenal Cortex Hormones; Cortisone; Duodenal Ulcer; Fluorouracil; Geriatrics; Oxyphenbutazone; Salic | 1964 |
Anti-inflammatory and ulcerogenic effects and pharmacokinetics of oxyphenbutazone in protein deficient rats.
Topics: Animals; Carrageenan; Dermatitis, Atopic; Dietary Proteins; Kinetics; Male; Oxyphenbutazone; Protein | 1980 |
Plasma exchange in severe rhesus disease.
Topics: Animals; Apazone; Humans; Oxyphenbutazone; Phenylbutazone; Rats; Stomach Ulcer; Triazines | 1977 |
Effect of captopril on oxyphenbutazone and ethanol-induced gastric lesions in rats.
Topics: Animals; Captopril; Ethanol; Indomethacin; Male; Oxyphenbutazone; Rats; Rats, Inbred Strains; Stomac | 1990 |
Comparison of the effects of captopril and enalapril on oxyphenbutazone and ethanol-induced gastric lesions in rats.
Topics: Animals; Captopril; Enalapril; Ethanol; Male; Oxyphenbutazone; Rats; Rats, Inbred Strains; Stomach U | 1990 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
Species differences in susceptibility to the gastro-ulcerogenic action of anti-inflammatory agents.
Topics: Administration, Oral; Ambystoma; Animals; Anti-Inflammatory Agents; Cricetinae; Dose-Response Relati | 1974 |
Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cordotomy; Dose-Response Relationship, Drug; Femal | 1973 |
[Ketazon not more gentle to the stomach than Blutazolidin].
Topics: Humans; Oxyphenbutazone; Phenylbutazone; Stomach Ulcer | 1972 |
Pharmacological investigations of benzothiazoline derivatives.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Benzyl Compounds; Body Temperature; Carrageen | 1972 |
[Use of antiphlogistics for athletic injuries].
Topics: Analgesics; Athletic Injuries; Central Nervous System Diseases; Humans; Indomethacin; Male; Oxyphenb | 1969 |