oxyphenbutazone has been researched along with Extravascular Hemolysis in 9 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxyphenbutazone was photooxidized in the presence of Rose Bengal, the latter being a photosensitizer." | 1.27 | Reactions of oxyphenbutazone with active oxygen species. ( Dimitrova, DE; Liochev, SI; Russanov, EM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Minta, JO | 1 |
| Urowitz, MB | 1 |
| Smythe, HA | 1 |
| Isenman, DE | 1 |
| Dimitrova, DE | 1 |
| Liochev, SI | 1 |
| Russanov, EM | 1 |
| Roubal, Z | 1 |
| Grimová, J | 1 |
| Nĕmecek, O | 1 |
| Cepelák, V | 1 |
| Jobin, F | 1 |
| Gagnon, FT | 1 |
| Kalbhen, DA | 1 |
| Gelderblom, P | 1 |
| Domenjoz, R | 1 |
| Fujihira, E | 2 |
| Otomo, S | 2 |
| Mizushima, Y | 1 |
| Sakai, S | 1 |
| Yamaura, M | 1 |
| Brown, JH | 1 |
| Mackey, HK | 1 |
9 other studies available for oxyphenbutazone and Extravascular Hemolysis
| Article | Year |
|---|---|
Effect on the human complement system of the major non-steroidal anti-inflammatory drugs: aspirin, indomethacin, phenylbutazone, oxyphenbutazone and sulindac.
Topics: Anti-Inflammatory Agents; Aspirin; Centrifugation, Density Gradient; Chromatography, Gel; Complement | 1983 |
Reactions of oxyphenbutazone with active oxygen species.
Topics: Animals; Hemolysis; Light; Oxygen; Oxyphenbutazone; Rats; Superoxides | 1987 |
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depressio | 1972 |
Platelet reactions and immune processes. IV. The inhibition of complement by pyrazole compounds and other inhibitors of platelet reactions.
Topics: Animals; Blood Coagulation; Blood Platelets; Chloroquine; Complement Inactivator Proteins; Erythrocy | 1970 |
Effects of antirheumatic drugs on human erythrocyte membranes.
Topics: Aminobenzoates; Analgesics; Antipyrine; Aspirin; Barbiturates; Benzoates; Cell Membrane; Erythrocyte | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. II. On UV-induced canine erythrocyte hemolysisand lipid peroxidation, on UV-induced peroxide formation in extracted lipid, and on irradiated lipid-induced hemolysis].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Capillary Permeability; Chloroquine; Dogs | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. I. On hemolysis and lipid peroxidation induced by H202 in canine erythrocyte].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Cell Membrane; Chloroquine; Dogs; Erythro | 1970 |
Mode of stabilizing action of non-steroid anti-inflammatory drugs on erythrocyte membrane.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Cell Membrane; Dogs; Ery | 1970 |
Further studies on the erythrocyte anti-inflammatory assay.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Dimethyl Sulfoxide; Erythrocytes; Estrog | 1968 |