oxyphenbutazone has been researched along with Equine Diseases in 4 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenylbutazone was given orally to 2 groups of horses and the plasma levels of the drug and its 2 principal metabolites oxyphenbutazone and gamma-hydroxyphenylbutazone measured by high performance liquid chromatography." | 1.26 | Pharmacokinetics of phenylbutazone and its metabolites in the horse. ( Gerring, EL; Lees, P; Taylor, JB, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higgins, AJ | 1 |
| Lees, P | 2 |
| Taylor, JB | 2 |
| Gerring, EL | 1 |
| Hopes, R | 1 |
| Gorman, HA | 1 |
| Wolff, WA | 1 |
| Frost, WW | 1 |
| Lumb, WV | 1 |
| Nelson, AW | 1 |
4 other studies available for oxyphenbutazone and Equine Diseases
| Article | Year |
|---|---|
Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cell Migration Inhibition; Dinoprostone; Exudates and Transud | 1984 |
Pharmacokinetics of phenylbutazone and its metabolites in the horse.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Horse Diseases; Horses; Kinetics; Lameness, Animal; | 1981 |
Uses and misuses of anti-inflammatory drugs in racehorses. 1.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Glucocorticoids; | 1972 |
Effect of oxyphenylbutazone on surgical wounds of horses.
Topics: Animals; Female; Horse Diseases; Horses; Inflammation; Male; Oxyphenbutazone; Surgical Wound Infecti | 1968 |