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oxyphenbutazone and Drug Hypersensitivity

oxyphenbutazone has been researched along with Drug Hypersensitivity in 9 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, DC1
Littlejohns, DW1
Assem, ES1
Kennedy, CT1
Paschoud, JM1
Almeyda, J1
Levantine, A1
Kimmig, J1
Widhammer, M1
Frenger, W1
Nayyar, KC1
Pasricha, JS1
Hartl, W1
Puxeddu, A1
Wiegershausen, B1

Reviews

1 review available for oxyphenbutazone and Drug Hypersensitivity

ArticleYear
Drug reactions. XX. Cutaneous reactions to anticonvulsants.
    The British journal of dermatology, 1972, Volume: 87, Issue:6

    Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dermatitis, Ex

1972

Trials

1 trial available for oxyphenbutazone and Drug Hypersensitivity

ArticleYear
[Drug side-effects from the pharmacological viewpoint].
    Zeitschrift fur arztliche Fortbildung, 1969, Jun-15, Volume: 63, Issue:12

    Topics: Acetates; Aminosalicylic Acids; Animals; Anticoagulants; Drug Hypersensitivity; Drug-Related Side Ef

1969

Other Studies

7 other studies available for oxyphenbutazone and Drug Hypersensitivity

ArticleYear
Letter: diffuse pulmonary disorder caused by oxyphenbutazone.
    British medical journal, 1975, May-31, Volume: 2, Issue:5969

    Topics: Aged; Drug Hypersensitivity; Female; Humans; Lung Diseases; Oxyphenbutazone

1975
Immunological evidence of two forms of allergy to pyrazolone drugs.
    Rheumatology and rehabilitation, 1973, Volume: 12, Issue:2

    Topics: Aged; Drug Eruptions; Drug Hypersensitivity; Female; Fever; Histamine Release; Humans; Immunoglobuli

1973
[Vasculitis allergica cutis caused by phenylbutazone].
    Dermatologica, 1966, Volume: 133, Issue:1

    Topics: Aged; Aminopyrine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Oxyphen

1966
[Allergy and surgery].
    Langenbecks Archiv fur Chirurgie, 1966, Volume: 316

    Topics: Adult; Aged; Anti-Bacterial Agents; Ascorbic Acid; Drug Hypersensitivity; Erythema Multiforme; Femal

1966
[Efficacy and compatibility of bumadizone-Ca in rheumatoid diseases. A comparison with oxyphenbutazone].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Dose-Response Relationshi

1973
Fixed drug eruption to oxyphenbutazone and phenylbutazone.
    Dermatologica, 1972, Volume: 144, Issue:4

    Topics: Adult; Drug Hypersensitivity; Erythema; Female; Humans; Oxyphenbutazone; Phenylbutazone; Pruritus; S

1972
[On the problem of specificity of drug-allergic immune reactions by aminophenazone-containing antirheumatic aents].
    Klinische Wochenschrift, 1966, Jan-01, Volume: 44, Issue:1

    Topics: Aminopyrine; Animals; Antigen-Antibody Reactions; Antipyrine; Complement Fixation Tests; Drug Hypers

1966