oxyphenbutazone has been researched along with Deficiency, Protein in 2 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dietary protein deficiency was associated with a decrease in the conversion of phenylbutazone into oxyphenbutazone by 9000 x g liver supernatant of protein-deficient rats." | 1.26 | Influence of dietary portein on the disposition and metabolism of phenylbutazone in rats. ( Varma, DR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Varma, DR | 2 |
2 other studies available for oxyphenbutazone and Deficiency, Protein
| Article | Year |
|---|---|
Influence of dietary portein on the disposition and metabolism of phenylbutazone in rats.
Topics: Animals; Biotransformation; Dietary Proteins; Half-Life; In Vitro Techniques; Liver; Male; Oxyphenbu | 1980 |
Anti-inflammatory and ulcerogenic effects and pharmacokinetics of oxyphenbutazone in protein deficient rats.
Topics: Animals; Carrageenan; Dermatitis, Atopic; Dietary Proteins; Kinetics; Male; Oxyphenbutazone; Protein | 1980 |