oxyphenbutazone has been researched along with Anemia, Hypoplastic in 23 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirteen out of 17 deaths from agranulocytosis were attributed to co-trimoxazole treatment." | 1.26 | Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone. ( Inman, WH, 1977) |
| "Cases of drug-induced aplastic anaemia, haemolytic anaemia, thrombocytopenia, and agranulocytosis reported to the Swedish Adverse Drug Reaction Committee during the five-year period 1966-70 have been analysed and compared with cases of the same cytopenias from "all" causes." | 1.25 | Drug-induced blood dyscrasias in Sweden. ( Böttiger, LE; Westerholm, B, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BELFRAGE, S | 1 |
| Vincent, PC | 1 |
| Heimpel, H | 1 |
| Heit, W | 1 |
| Haak, HL | 1 |
| Inman, WH | 1 |
| Böttiger, LE | 5 |
| Hausmann, K | 2 |
| Skrandies, G | 2 |
| Sachtleben, P | 2 |
| Girdwood, RH | 1 |
| Chaplin, S | 2 |
| Bull, O | 1 |
| Skobba, TJ | 1 |
| Westerholm, B | 4 |
| Pilewski, RM | 1 |
| Ellis, LD | 1 |
| Sapira, JD | 1 |
| Mark, R | 1 |
| Brownlie, BE | 1 |
| Strang, PJ | 1 |
| Segagni, E | 1 |
| Mina, G | 1 |
| Varaldo, G | 1 |
| Gabriel, B | 1 |
| Gabriel, BJ | 1 |
| Olmer, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Collection of Blood, Stool, Bone Marrow and/or Tissue Samples From Subjects With Hepatitis-Associated Aplastic Anemia[NCT00050115] | 9 participants (Actual) | Observational | 2003-03-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for oxyphenbutazone and Anemia, Hypoplastic
| Article | Year |
|---|---|
In vitro evidence of drug action in aplastic anemia.
Topics: Acetanilides; Anemia, Aplastic; Animals; Benzene; Cell Differentiation; Chloramphenicol; Disease Mod | 1984 |
Drug-induced aplastic anaemia: clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici | 1980 |
Experimental drug-induced aplastic anaemia.
Topics: Anemia, Aplastic; Animals; Benzene; Busulfan; Chloramphenicol; Colony-Forming Units Assay; Disease M | 1980 |
Bone marrow depression due to mianserin, phenylbutazone, oxyphenbutazone, and chloramphenicol--Part I.
Topics: Agranulocytosis; Anemia, Aplastic; Bone Marrow; Cell Membrane; Chloramphenicol; Dibenzazepines; DNA | 1986 |
Bone marrow depression due to mianserin, phenylbutazone, oxyphenbutazone, and chloramphenicol--Part II.
Topics: Anemia, Aplastic; Bone Marrow; Chloramphenicol; Dose-Response Relationship, Drug; Erythropoiesis; Hu | 1986 |
18 other studies available for oxyphenbutazone and Anemia, Hypoplastic
| Article | Year |
|---|---|
[SERIOUS ILLNESS ASSOCIATED WITH TANDERIL TREATMENT].
Topics: Anemia; Anemia, Aplastic; Bone Marrow Diseases; Exanthema; Fever; Geriatrics; Nephrosis; Oxyphenbuta | 1964 |
Phenylbutazone, oxyphenbutazone labeling revised.
Topics: Agranulocytosis; Anemia, Aplastic; Drug Labeling; Humans; Oxyphenbutazone; Phenylbutazone | 1984 |
Phenylbutazone and oxyphenbutazone: time to call a halt.
Topics: Anemia, Aplastic; Bone Marrow; Humans; Oxyphenbutazone; Phenylbutazone | 1984 |
Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone.
Topics: Adolescent; Adult; Age Factors; Aged; Agranulocytosis; Anemia, Aplastic; Child; Death Certificates; | 1977 |
Phenylbutazone, oxyphenbutazone and aplastic anaemia.
Topics: Anemia, Aplastic; Chloramphenicol; Humans; Oxyphenbutazone; Phenylbutazone | 1977 |
[Current aspects of iatrogenic lesions of the bone marrow].
Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol; | 1976 |
Haematological side-effects of drugs.
Topics: Ampicillin; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Megaloblastic; Anti-Inflammatory Agents, No | 1976 |
Editorial: Drug-induced aplastic anaemia.
Topics: Anemia, Aplastic; Anti-Bacterial Agents; Blood Cell Count; Blood Transfusion; Bone Marrow Examinatio | 1974 |
[Present aspects of bone marrow lesions due to drugs (author's transl)].
Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse React | 1974 |
[Acute myelogenous leukemia. Associated with oxyphenbutazone induced aplastic anemia].
Topics: Aged; Anemia, Aplastic; Humans; Leukemia, Myeloid; Male; Oxyphenbutazone; Thrombophlebitis | 1974 |
Drug-induced blood dyscrasias in Sweden.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Agranulocytosis; Anemia, Aplastic; Anemi | 1973 |
Oxyphenbutazone and aplastic anemia.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Male; Oxyphenbutazone | 1972 |
Aplastic anaemia. I. Incidence and aetiology.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Female; Humans; | 1972 |
Aplastic anaemia. II. Drug-induced aplastic anaemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Female; Humans; | 1972 |
Aplastic anaemia. 3. Aplastic anaemia and infectious hepatitis.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Chloramphenicol; Female; Hepatitis A; Humans; Male; Oxyph | 1972 |
Oxyphenbutazone (Tanderil) and blood dyscrasia.
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Bone Marrow; Female; Hematologic Diseases; Hematopoi | 1969 |
[On a case of partial aplastic myelosis during rheumatic disease].
Topics: Agranulocytosis; Analgesics; Anemia, Aplastic; Antihypertensive Agents; Child; Female; Humans; Oxyph | 1969 |
[Bone marrow aplasia in the course of anti-epileptic treatments].
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Ethosuximide; Female; Humans; Hydantoins; Male; Oxyphenb | 1966 |