oxyphenbutazone has been researched along with Anemia, Hemolytic in 3 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cases of drug-induced aplastic anaemia, haemolytic anaemia, thrombocytopenia, and agranulocytosis reported to the Swedish Adverse Drug Reaction Committee during the five-year period 1966-70 have been analysed and compared with cases of the same cytopenias from "all" causes." | 1.25 | Drug-induced blood dyscrasias in Sweden. ( Böttiger, LE; Westerholm, B, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Girdwood, RH | 1 |
| Böttiger, LE | 1 |
| Westerholm, B | 1 |
| Goedee, HW | 1 |
| Altland, K | 1 |
1 review available for oxyphenbutazone and Anemia, Hemolytic
| Article | Year |
|---|---|
[Genetically dependent variability of drug effects].
Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temp | 1970 |
2 other studies available for oxyphenbutazone and Anemia, Hemolytic
| Article | Year |
|---|---|
Haematological side-effects of drugs.
Topics: Ampicillin; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Megaloblastic; Anti-Inflammatory Agents, No | 1976 |
Drug-induced blood dyscrasias in Sweden.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Agranulocytosis; Anemia, Aplastic; Anemi | 1973 |