oxyphenbutazone has been researched along with Aging in 3 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic variables were calculated, using 1- and 2-compartment open models." | 1.29 | Pharmacokinetics of phenylbutazone in neonatal foals. ( Crisman, MV; Gerken, DF; Sams, RA; Wilcke, JR, 1993) |
| "4 mg/kg bodyweight) of phenylbutazone was administered intravenously and orally to six Welsh mountain ponies to provide data on the pharmacokinetics and bioavailability of the drug." | 1.27 | Pharmacokinetics of phenylbutazone in two age groups of ponies: a preliminary study. ( Lees, P; Maitho, TE; Taylor, JB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heimpel, H | 1 |
| Heit, W | 1 |
| Wilcke, JR | 1 |
| Crisman, MV | 1 |
| Sams, RA | 1 |
| Gerken, DF | 1 |
| Lees, P | 1 |
| Maitho, TE | 1 |
| Taylor, JB | 1 |
1 review available for oxyphenbutazone and Aging
| Article | Year |
|---|---|
Drug-induced aplastic anaemia: clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici | 1980 |
2 other studies available for oxyphenbutazone and Aging
| Article | Year |
|---|---|
Pharmacokinetics of phenylbutazone in neonatal foals.
Topics: Aging; Animals; Animals, Newborn; Female; Horses; Injections, Intravenous; Male; Metabolic Clearance | 1993 |
Pharmacokinetics of phenylbutazone in two age groups of ponies: a preliminary study.
Topics: Administration, Oral; Aging; Animals; Biological Availability; Female; Horses; Injections, Intraveno | 1985 |