oxyphenbutazone has been researched along with Adverse Drug Event in 7 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Hausmann, K | 2 |
| Skrandies, G | 2 |
| Sachtleben, P | 2 |
| Luyckx, A | 1 |
| Scheen, A | 1 |
| Van Cauwenberge, H | 1 |
| Bruinsma, W | 1 |
| Rintelen, F | 1 |
| Meyer, JP | 1 |
| Wiegershausen, B | 1 |
1 trial available for oxyphenbutazone and Adverse Drug Event
| Article | Year |
|---|---|
[Drug side-effects from the pharmacological viewpoint].
Topics: Acetates; Aminosalicylic Acids; Animals; Anticoagulants; Drug Hypersensitivity; Drug-Related Side Ef | 1969 |
6 other studies available for oxyphenbutazone and Adverse Drug Event
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
[Current aspects of iatrogenic lesions of the bone marrow].
Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol; | 1976 |
[Drug update].
Topics: Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Oxyphenbutazone; Phenylbutazo | 1985 |
[Present aspects of bone marrow lesions due to drugs (author's transl)].
Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse React | 1974 |
Adverse reaction profiles of drug eruptions.
Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Er | 1972 |
[Realization of nonocular dangers resulting from general medical therapy in ocular affections].
Topics: Acetazolamide; Aged; Anticoagulants; Diuretics; Drug-Related Side Effects and Adverse Reactions; Ede | 1970 |