oxymetazoline has been researched along with Sinusitis in 12 studies
Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.
Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to study changes in sales and prescribing of nasal decongestants containing oxymetazoline or xylometazoline, changes in number of physician visits for rhinitis and sinusitis, and changes in public expenditures for physician visits due to the switch of these drugs from prescription to over-the-counter status in Sweden in 1989." | 3.70 | The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits. ( Isacson, D; Lundberg, L, 1999) |
| "The aim of this study was to evaluate the incidence of paranasal sinusitis and the histologic changes in the sinus mucosa after long-term administration of topical nasal decongestants, phenylephrine and oxymetazoline." | 3.69 | Paranasal sinusitis after long-term use of topical nasal decongestants. ( Jeon, SY; Kim, HS; Min, YG; Son, YI; Suh, SH; Yoon, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schechtman, SA | 1 |
| Wertz, AP | 1 |
| Shanks, A | 1 |
| Thompson, A | 1 |
| Tremper, K | 1 |
| Pynnonen, MA | 1 |
| Healy, DW | 1 |
| Song, XH | 1 |
| Zhang, L | 1 |
| Han, DM | 1 |
| Wang, KJ | 1 |
| Wang, H | 1 |
| Zhang, W | 1 |
| Bende, M | 1 |
| Fukami, M | 1 |
| Arfors, KE | 1 |
| Mark, J | 1 |
| Stierna, P | 1 |
| Intaglietta, M | 1 |
| Min, YG | 1 |
| Kim, HS | 1 |
| Suh, SH | 1 |
| Jeon, SY | 1 |
| Son, YI | 1 |
| Yoon, S | 1 |
| Lundberg, L | 1 |
| Isacson, D | 1 |
| Negley, JE | 1 |
| Krause, H | 1 |
| Pawar, S | 1 |
| Reeves-Hoché, MK | 1 |
| Inanli, S | 1 |
| Oztürk, O | 1 |
| Korkmaz, M | 1 |
| Tutkun, A | 1 |
| Batman, C | 1 |
| Riegle, EV | 1 |
| Gunter, JB | 1 |
| Lusk, RP | 1 |
| Muntz, HR | 1 |
| Weiss, KL | 1 |
| Maes, JJ | 1 |
| Clement, PA | 1 |
| Ten Eyck, TG | 1 |
| Schleuning, A | 1 |
| Tanaka, M | 1 |
| Neffson, AH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hot Saline Irrigation vs Room Temperature Saline Irrigation in the Control of Intraoperative Bleeding During Functional Endoscopic Sinus Surgery (FESS)[NCT01717274] | 60 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for oxymetazoline and Sinusitis
| Article | Year |
|---|---|
RinoFlow nasal wash and sinus system as a mechanism to deliver medications to the paranasal sinuses: results of a radiolabeled pilot study.
Topics: Administration, Inhalation; Adolescent; Adult; Drug Delivery Systems; Equipment Design; Female; Huma | 1999 |
The effects of topical agents of fluticasone propionate, oxymetazoline, and 3% and 0.9% sodium chloride solutions on mucociliary clearance in the therapy of acute bacterial rhinosinusitis in vivo.
Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Analysis of Variance; Androstadiene | 2002 |
Comparison of vasoconstrictors for functional endoscopic sinus surgery in children.
Topics: Blood Pressure; Child; Child, Preschool; Chronic Disease; Cocaine; Double-Blind Method; Heart Rate; | 1992 |
The usefulness of irrigation of the maxillary sinus in children with maxillary sinusitis on the basis of the Water's X-ray.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Combined Modality Therapy; Humans; Imidazoles; Maxil | 1987 |
8 other studies available for oxymetazoline and Sinusitis
| Article | Year |
|---|---|
Preoperative β-blockade and hypertension in the first hour of functional endoscopic sinus surgery.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anesthetics, Local; Chronic Disease; Dr | 2017 |
[Effects of oxymetazoline hydrochloride on ex vivo human nasal cilia movement measured with high-speed digital microscopy].
Topics: Cells, Cultured; Cilia; Humans; Microscopy; Mucociliary Clearance; Nasal Mucosa; Oxymetazoline; Sinu | 2008 |
Effect of oxymetazoline nose drops on acute sinusitis in the rabbit.
Topics: Acute Disease; Administration, Intranasal; Animals; Drug Evaluation; Maxillary Sinus; Nasal Deconges | 1996 |
Paranasal sinusitis after long-term use of topical nasal decongestants.
Topics: Administration, Topical; Animals; Nasal Decongestants; Nasal Mucosa; Nerve Degeneration; Oxymetazoli | 1996 |
The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Prescriptions; Female; Health Expenditures; H | 1999 |
Nasal decongestants in otorhinolaryngology.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Nasal Decongestants; Oxymetazoline; Resp | 1966 |
[Clinical use of Nasibin for chronic sinusitis].
Topics: Adolescent; Adult; Child; Female; Humans; Male; Nasal Decongestants; Oxymetazoline; Sinusitis | 1966 |
A topical nasal decongestant for children.
Topics: Child, Preschool; Cresols; Female; Foreign Bodies; Fractures, Bone; Humans; Imidazoles; Infant; Male | 1968 |