Page last updated: 2024-11-02

oxymetazoline and Rhinitis

oxymetazoline has been researched along with Rhinitis in 47 studies

Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to summarise the evidence for efficacy of combination treatment of intranasal corticosteroid spray with oxymetazoline hydrochloride nasal spray for chronic rhinitis."9.22Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review. ( Camacho, M; Neighbors, CL; Salvador, CF; Tsai, P; Zhu, B, 2022)
"We sought to explore the benefit of oxymetazoline (Oxymet) plus INS on nasal congestion without inducing rhinitis medicamentosa."9.22The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial. ( Assanasen, P; Pradubpongsa, P; Tantilipikorn, P; Thongngarm, T, 2016)
"A prospective placebo-controlled double-blind study investigated the question whether oxymetazoline has a clinically relevant impact on the duration of acute rhinitis."9.11[Investigation of the effect of oxymetazoline on the duration of rhinitis. results of a placebo-controlled double-blind study in patients with acute rhinitis]. ( Reinecke, S; Tschaikin, M, 2005)
"This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis."9.10[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003)
"A new administration form of the nasal decongestant oxymetazoline and its effects on maxillary ostial patency were investigated in 5 healthy individuals and 20 patients with acute rhinitis."9.07Effects of a new administration form of oxymetazoline on maxillary ostial patency in healthy individuals and patients with acute rhinitis. ( Ackerhans, M; Jannert, M; Tönnesson, M, 1994)
"The absolute bioavailability (f) and pharmacokinetics of transnasal butorphanol were evaluated in patients experiencing rhinitis."9.07The absolute bioavailability of transnasal butorphanol in patients experiencing rhinitis. ( Barbhaiya, RH; Pittman, KA; Robinson, DS; Shyu, WC, 1993)
"According to the results, xylitol solution is effective as mometasone, usable and well-priced in the treatment of rhinitis medicamentosa."7.91Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study. ( Cam, B; Gergin, O; Midi, A; Sari, M, 2019)
"This study aimed to summarise the evidence for efficacy of combination treatment of intranasal corticosteroid spray with oxymetazoline hydrochloride nasal spray for chronic rhinitis."5.22Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review. ( Camacho, M; Neighbors, CL; Salvador, CF; Tsai, P; Zhu, B, 2022)
"We sought to explore the benefit of oxymetazoline (Oxymet) plus INS on nasal congestion without inducing rhinitis medicamentosa."5.22The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial. ( Assanasen, P; Pradubpongsa, P; Tantilipikorn, P; Thongngarm, T, 2016)
"A prospective placebo-controlled double-blind study investigated the question whether oxymetazoline has a clinically relevant impact on the duration of acute rhinitis."5.11[Investigation of the effect of oxymetazoline on the duration of rhinitis. results of a placebo-controlled double-blind study in patients with acute rhinitis]. ( Reinecke, S; Tschaikin, M, 2005)
"This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis."5.10[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003)
"A randomized double-blind parallel study with 20 healthy volunteers was performed to examine the effect of oxymetazoline nasal spray on the development of rhinitis medicamentosa."5.08Four-week use of oxymetazoline nasal spray (Nezeril) once daily at night induces rebound swelling and nasal hyperreactivity. ( Graf, P; Hallén, H; Juto, JE, 1995)
"A new administration form of the nasal decongestant oxymetazoline and its effects on maxillary ostial patency were investigated in 5 healthy individuals and 20 patients with acute rhinitis."5.07Effects of a new administration form of oxymetazoline on maxillary ostial patency in healthy individuals and patients with acute rhinitis. ( Ackerhans, M; Jannert, M; Tönnesson, M, 1994)
"The absolute bioavailability (f) and pharmacokinetics of transnasal butorphanol were evaluated in patients experiencing rhinitis."5.07The absolute bioavailability of transnasal butorphanol in patients experiencing rhinitis. ( Barbhaiya, RH; Pittman, KA; Robinson, DS; Shyu, WC, 1993)
"According to the results, xylitol solution is effective as mometasone, usable and well-priced in the treatment of rhinitis medicamentosa."3.91Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study. ( Cam, B; Gergin, O; Midi, A; Sari, M, 2019)
"The nasal decongestant oxymetazoline (OMZ) is frequently used in the topical treatment of rhinitis/sinusitis."3.74Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells. ( Jonuleit, H; Knop, J; Koelsch, S; Tuettenberg, A, 2007)
"105 patients collected from chronic simple rhinitis, chronic hypertrophic rhinitis and perennial allergic rhinitis were treated with daphnlin spray (daphnlin group) or ephedrine spray (ephedrine group)."3.70[The curative effect of daphnlin spray on treating rhinitis]. ( Huang, X; Tan, H; Yue, J, 1999)
"The aim was to study changes in sales and prescribing of nasal decongestants containing oxymetazoline or xylometazoline, changes in number of physician visits for rhinitis and sinusitis, and changes in public expenditures for physician visits due to the switch of these drugs from prescription to over-the-counter status in Sweden in 1989."3.70The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits. ( Isacson, D; Lundberg, L, 1999)
" In conclusion, the long-term use of benzalkonium chloride in oxymetazoline nasal spray accentuates the severity of rhinitis medicamentosa in healthy volunteers."2.68Benzalkonium chloride in a decongestant nasal spray aggravates rhinitis medicamentosa in healthy volunteers. ( Graf, P; Hallén, H; Juto, JE, 1995)
" It is concluded that a nasal decongestant spray composed of a combination of vasoactive substance and benzalkonium chloride has a long-term adverse effect on the nasal mucosa."2.68Benzalkonium chloride in nasal decongestive sprays has a long-lasting adverse effect on the nasal mucosa of healthy volunteers. ( Graf, P; Hallén, H, 1995)
" Long-term use of placebo and benzalkonium chloride nasal sprays also caused an increase in nasal reactivity, but not to the same extent as with the nasal sprays containing oxymetazoline."2.68Effect on the nasal mucosa of long-term treatment with oxymetazoline, benzalkonium chloride, and placebo nasal sprays. ( Graf, P; Hallén, H, 1996)
"Our aim in this study is to reveal the expression of Vascular Endothelial Growth Factor (VEGF) and Inducible Nitric Oxide Synthase (iNOS) in the pathogenesis of rhinitis medicamentosa (RM), which occurs as a result of the overdose and long-term use of topical nasal decongestants."1.72The importance of vascular epithelial growth factor (VEGF) and inducible nitric oxide synthase (INOS) in rhinitis medicamentosa pathogenesis: An experimental rat model study. ( Bulut, F; Cumbul, A, 2022)
"Oxymetazoline or Salbutamol were prescribed according to best clinical practice guidelines."1.46Efficacy and usability of a novel nebulizer targeting both upper and lower airways. ( Hofmaier, S; Lau, S; Matricardi, PM; Perna, S; Pizzulli, A; Posa, D; Wagner, P, 2017)
"Nasal obstruction is caused by rebound swelling when the decongestive effect has disappeared."1.33[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa]. ( Bloching, M; Holzhausen, HJ; Knipping, S; Riederer, A, 2006)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199014 (29.79)18.7374
1990's14 (29.79)18.2507
2000's10 (21.28)29.6817
2010's5 (10.64)24.3611
2020's4 (8.51)2.80

Authors

AuthorsStudies
Neighbors, CL1
Salvador, CF1
Zhu, B1
Camacho, M1
Tsai, P1
Cumbul, A1
Bulut, F1
Cam, B1
Sari, M1
Midi, A1
Gergin, O1
Cengiz, B1
Bostancıklıoğlu, M1
Demir, T1
Karabulut, H1
Dokuyucu, R1
Ulaşlı, M1
Shakhova, EG1
Posa, D1
Pizzulli, A1
Wagner, P1
Perna, S1
Hofmaier, S1
Matricardi, PM1
Lau, S1
Thongngarm, T1
Assanasen, P1
Pradubpongsa, P1
Tantilipikorn, P1
Fabi, M1
Formigari, R1
Picchio, FM1
Tüttenberg, A1
Bielenberg, J1
Yue, J1
Huang, X1
Tan, H1
SLODKI, SJ1
MONTGOMERY, CA1
Dorn, M1
Hofmann, W1
Knick, E1
Reinecke, S2
Tschaikin, M2
Knipping, S1
Holzhausen, HJ1
Riederer, A1
Bloching, M1
Tuettenberg, A1
Koelsch, S1
Knop, J1
Jonuleit, H1
Straszek, SP1
Schlünssen, V1
Sigsgaard, T1
Pedersen, OF1
Bende, M2
Ekedahl, C2
Geterud, A3
Petruson, B2
Aust, R2
Odkvist, L2
Rundcrantz, H1
Graf, P5
Hallén, H4
Juto, JE2
Wilhelmson, B1
Ackerhans, M1
Jannert, M1
Tönnesson, M1
Shyu, WC1
Pittman, KA1
Robinson, DS1
Barbhaiya, RH1
Yoo, JK1
Seikaly, H1
Calhoun, KH1
Hummel, T1
Rothbauer, C1
Pauli, E1
Kobal, G1
Lundberg, L1
Isacson, D1
Dowley, AC1
Homer, JJ1
Inanli, S1
Oztürk, O1
Korkmaz, M1
Tutkun, A1
Batman, C1
Redemsky, J1
Hansell, P1
Intaglietta, M1
Arfors, KE1
Howarth, P1
Walsh, S1
Robinson, C1
Osguthorpe, JD1
Shirley, R1
Blakley, BW1
Wilson, KS1
Rüggeberg, F1
Ten Eyck, TG1
Schleuning, A1
Stride, RD1
Neffson, AH1
Connell, JT1
Neidorff, AH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Proof of Concept Study to Evaluate if Concomitant Topical Intranasal Steroid Prevents Tolerance and Rebound Congestion Due to Regular Oxymetazoline in Persistent Allergic Rhinitis.[NCT00846326]Phase 40 participants (Actual)InterventionalWithdrawn (stopped due to The suppliers were unable to provide the investigational medicinal product (IMP))
A Proof of Concept Study to Evaluate Differential Tachyphylaxis of Alpha 1 and Alpha 2 Adrenoreceptor Mediated Decongestant Response to Oxymetazoline and Its Acute Reversal by Corticosteroid in Healthy Volunteers[NCT00487032]Phase 419 participants (Actual)Interventional2008-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for oxymetazoline and Rhinitis

ArticleYear
Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review.
    The Journal of laryngology and otology, 2022, Volume: 136, Issue:1

    Topics: Administration, Intranasal; Chronic Disease; Glucocorticoids; Humans; Nasal Decongestants; Oxymetazo

2022

Trials

21 trials available for oxymetazoline and Rhinitis

ArticleYear
[Comparative study of the efficacy of combined nasal topical drug and topical decongestants in the treatment of acute rhinosinusitis].
    Vestnik otorinolaringologii, 2020, Volume: 85, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Double-Blind Method; Female; Humans; Male; Middle Age

2020
The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial.
    Asian Pacific journal of allergy and immunology, 2016, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Budesonide; Chronic Disease; Double-Blind Method; Drug Therapy, C

2016
[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis].
    HNO, 2003, Volume: 51, Issue:10

    Topics: Acute Disease; Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Common Cold; Dou

2003
[Investigation of the effect of oxymetazoline on the duration of rhinitis. results of a placebo-controlled double-blind study in patients with acute rhinitis].
    MMW Fortschritte der Medizin, 2005, Oct-06, Volume: 147 Suppl 3

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Nasal Decongestants; O

2005
[Investigation of the effect of oxymetazoline on the duration of rhinitis].
    MMW Fortschritte der Medizin, 2005, Oct-13, Volume: 147, Issue:41

    Topics: Adolescent; Adult; Child; Double-Blind Method; Female; Humans; Male; Nasal Decongestants; Nasal Obst

2005
A comparative preference study between xylometazoline nasal dose spray (Otrivin) and oxymetazoline single-dose pipettes (Nezeril).
    Rhinology, 1983, Volume: 21, Issue:3

    Topics: Adult; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Nasal Decongestants; Oxymetazolin

1983
[Comparison between xylometazoline in a dosage spray and oxymetazoline in one dose pipettes].
    Lakartidningen, 1983, May-04, Volume: 80, Issue:18

    Topics: Adult; Aerosols; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Middle Aged; Oxymetazol

1983
Benzalkonium chloride in a decongestant nasal spray aggravates rhinitis medicamentosa in healthy volunteers.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:5

    Topics: Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Double-Blind Method; Female; Hu

1995
Benzalkonium chloride in nasal decongestive sprays has a long-lasting adverse effect on the nasal mucosa of healthy volunteers.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:5

    Topics: Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Double-Blind Method; Drug Admin

1995
Four-week use of oxymetazoline nasal spray (Nezeril) once daily at night induces rebound swelling and nasal hyperreactivity.
    Acta oto-laryngologica, 1995, Volume: 115, Issue:1

    Topics: Administration, Intranasal; Adult; Double-Blind Method; Female; Humans; Hypersensitivity; Male; Nasa

1995
Effects of a new administration form of oxymetazoline on maxillary ostial patency in healthy individuals and patients with acute rhinitis.
    Acta oto-laryngologica. Supplementum, 1994, Volume: 515

    Topics: Acute Disease; Administration, Intranasal; Double-Blind Method; Female; Humans; Male; Maxillary Sinu

1994
The absolute bioavailability of transnasal butorphanol in patients experiencing rhinitis.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:6

    Topics: Absorption; Administration, Intranasal; Adult; Biological Availability; Butorphanol; Drug Interactio

1993
Effect on the nasal mucosa of long-term treatment with oxymetazoline, benzalkonium chloride, and placebo nasal sprays.
    The Laryngoscope, 1996, Volume: 106, Issue:5 Pt 1

    Topics: Administration, Intranasal; Adolescent; Adult; Benzalkonium Compounds; Double-Blind Method; Female;

1996
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
    Rhinology, 1996, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema

1996
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
    Rhinology, 1996, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema

1996
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
    Rhinology, 1996, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema

1996
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
    Rhinology, 1996, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema

1996
Extended use of topical nasal decongestants.
    The Laryngoscope, 1997, Volume: 107, Issue:1

    Topics: Humans; Nasal Decongestants; Nasal Obstruction; Oxymetazoline; Rhinitis; Sympathomimetics

1997
Extended use of topical nasal decongestants.
    The Laryngoscope, 1997, Volume: 107, Issue:1

    Topics: Humans; Nasal Decongestants; Nasal Obstruction; Oxymetazoline; Rhinitis; Sympathomimetics

1997
Extended use of topical nasal decongestants.
    The Laryngoscope, 1997, Volume: 107, Issue:1

    Topics: Humans; Nasal Decongestants; Nasal Obstruction; Oxymetazoline; Rhinitis; Sympathomimetics

1997
Extended use of topical nasal decongestants.
    The Laryngoscope, 1997, Volume: 107, Issue:1

    Topics: Humans; Nasal Decongestants; Nasal Obstruction; Oxymetazoline; Rhinitis; Sympathomimetics

1997
Effects of the nasal decongestant oxymetazoline on human olfactory and intranasal trigeminal function in acute rhinitis.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:7

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Male; Nasal Decongestants; Olfactory Nerv

1998
The effect of inferior turbinate hypertrophy on nasal spray distribution to the middle meatus.
    Clinical otolaryngology and allied sciences, 2001, Volume: 26, Issue:6

    Topics: Administration, Intranasal; Aerosols; Cross-Over Studies; Humans; Hypertrophy; Nasal Cavity; Nasal D

2001
The effects of topical agents of fluticasone propionate, oxymetazoline, and 3% and 0.9% sodium chloride solutions on mucociliary clearance in the therapy of acute bacterial rhinosinusitis in vivo.
    The Laryngoscope, 2002, Volume: 112, Issue:2

    Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Analysis of Variance; Androstadiene

2002
[Clinical test of oxymetazoline-HCl-nose drops for infants (Nasivin 0,01 per cent)].
    Zeitschrift fur Allgemeinmedizin, 1974, Apr-20, Volume: 50, Issue:11

    Topics: Clinical Trials as Topic; Humans; Imidazoles; Infant; Nasal Decongestants; Oxymetazoline; Rhinitis;

1974
Effectiveness of topical nasal decongestants.
    Annals of allergy, 1969, Volume: 27, Issue:11

    Topics: Adolescent; Adult; Airway Resistance; Clinical Trials as Topic; Common Cold; Female; Humans; Male; M

1969
Clinical note: double-blind comparison of the duration of effect of oxymetazoline and phenylephrine in children.
    Annals of allergy, 1966, Volume: 24, Issue:5

    Topics: Asthma; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Oxymetazoline; Phenylephrine; Rh

1966

Other Studies

25 other studies available for oxymetazoline and Rhinitis

ArticleYear
The importance of vascular epithelial growth factor (VEGF) and inducible nitric oxide synthase (INOS) in rhinitis medicamentosa pathogenesis: An experimental rat model study.
    Histology and histopathology, 2022, Volume: 37, Issue:3

    Topics: Animals; Edema; Nasal Mucosa; Nitric Oxide Synthase Type II; Oxymetazoline; Rats; Rats, Wistar; Rhin

2022
Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019, Volume: 276, Issue:11

    Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Male; Mometas

2019
Investigation of Cytotoxic Effects of Oxymetazoline on Lungs in a Rat Model of Rhinitis Medicamentosa.
    Current molecular pharmacology, 2021, 10-25, Volume: 14, Issue:4

    Topics: Animals; Lung; Nasal Decongestants; Oxymetazoline; Rats; Rats, Wistar; Rhinitis

2021
Efficacy and usability of a novel nebulizer targeting both upper and lower airways.
    Italian journal of pediatrics, 2017, Sep-29, Volume: 43, Issue:1

    Topics: Administration, Inhalation; Adolescent; Albuterol; Ambulatory Care Facilities; Asthma; Bronchodilato

2017
Are nasal decongestants safer than rhinitis? A case of oxymetazoline-induced syncope.
    Cardiology in the young, 2009, Volume: 19, Issue:6

    Topics: Bradycardia; Diagnosis, Differential; Echocardiography; Electrocardiography; Humans; Infant; Male; N

2009
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha

2009
[Rhinitis acuta: therapeutic approach with oxymetazoline].
    MMW Fortschritte der Medizin, 2010, Apr-08, Volume: 152 Suppl 1

    Topics: Administration, Intranasal; CD4-Positive T-Lymphocytes; Common Cold; Cytokines; Dendritic Cells; Dos

2010
["Of snakes and crocodiles": central side effects of nose drops and facts about rhinitis medicamentosa].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2011, Volume: 30, Issue:10

    Topics: Administration, Intranasal; Adult; Child, Preschool; Drug Combinations; Female; Hallucinations; Huma

2011
[The curative effect of daphnlin spray on treating rhinitis].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 1999, Volume: 13, Issue:10

    Topics: Administration, Inhalation; Adolescent; Adult; Ephedrine; Female; Humans; Male; Middle Aged; Nasal D

1999
CLINICAL COMPARISON OF OXYMETAZOLINE AND EPHEDRINE IN NASAL DECONGESTION.
    Current therapeutic research, clinical and experimental, 1965, Volume: 7

    Topics: Adolescent; Blood Pressure; Blood Pressure Determination; Drug Therapy; Ephedrine; Humans; Imidazole

1965
[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa].
    HNO, 2006, Volume: 54, Issue:10

    Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Capillary Permeability; Chronic Disease; Dose

2006
Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells.
    Experimental dermatology, 2007, Volume: 16, Issue:3

    Topics: Cells, Cultured; Cytokines; Dendritic Cells; Dose-Response Relationship, Drug; Enzyme-Linked Immunos

2007
Reference values for acoustic rhinometry in decongested school children and adults: the most sensitive measurement for change in nasal patency.
    Rhinology, 2007, Volume: 45, Issue:1

    Topics: Adult; Airway Resistance; Anatomy, Cross-Sectional; Asthma; Child; Dermatitis, Atopic; Dust; Female;

2007
Studies of blood flow in the human nasal mucosa.
    European journal of respiratory diseases. Supplement, 1983, Volume: 128 (Pt 2)

    Topics: Adult; Female; Histamine Release; Humans; Male; Nasal Mucosa; Oxymetazoline; Regional Blood Flow; Rh

1983
The effect of a local decongestant in acute rhinitis as related to body position.
    Rhinology, 1983, Volume: 21, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Oxymetazoline

1983
[Rhinitis medicamentosa, an increasing problem. Do nose drops adversely affect bacterial infections?].
    Lakartidningen, 1994, Dec-07, Volume: 91, Issue:49

    Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Humans; Imidazoles; Oxymetazoline; Rhinitis

1994
The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits.
    Scandinavian journal of primary health care, 1999, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Prescriptions; Female; Health Expenditures; H

1999
[Therapeutic experience within the scope of a multicentric study using the new Nasivin-gel].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1977, Jan-20, Volume: 53, Issue:2

    Topics: Adult; Drug Evaluation; Gels; Humans; Imidazoles; Oxymetazoline; Rhinitis

1977
Effect of oxymetazoline nose drops on vascular permeability of the nasal mucosa in the rabbit after provocation with leukotriene B4.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1992, Volume: 54, Issue:5

    Topics: Administration, Intranasal; Animals; Antibodies, Monoclonal; Capillary Permeability; Leukotriene B4;

1992
The comparative nasal effects of prostaglandin D2 in normal and rhinitic subjects.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Airway Resistance; Humans; Hypersensitivity, Immediate; Manometry; Nasal Cavity; Nasal Provocation T

1991
Neonatal respiratory distress from rhinitis medicamentosa.
    The Laryngoscope, 1987, Volume: 97, Issue:7 Pt 1

    Topics: Female; Humans; Infant, Newborn; Nasal Decongestants; Oxymetazoline; Phenylephrine; Respiratory Insu

1987
A simple reversible cause of infant upper airway obstruction.
    Minnesota medicine, 1986, Volume: 69, Issue:3

    Topics: Administration, Intranasal; Airway Obstruction; Humans; Infant, Newborn; Male; Oxymetazoline; Rhinit

1986
Nasal decongestants in otorhinolaryngology.
    Western medicine; the medical journal of the west, 1966, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Nasal Decongestants; Oxymetazoline; Resp

1966
Nasal decongestant therapy.
    The British journal of clinical practice, 1967, Nov-11, Volume: 21, Issue:11

    Topics: Biopsy; Chronic Disease; Epinephrine; Humans; Imidazoles; Nasal Decongestants; Oxymetazoline; Rhinit

1967
A topical nasal decongestant for children.
    Eye, ear, nose & throat monthly, 1968, Volume: 47, Issue:3

    Topics: Child, Preschool; Cresols; Female; Foreign Bodies; Fractures, Bone; Humans; Imidazoles; Infant; Male

1968