oxymetazoline has been researched along with Recrudescence in 6 studies
Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this retrospective study, 36 patients were given oxymetazoline as a first step in treatment for posterior epistaxis." | 7.70 | Oxymetazoline in the treatment of posterior epistaxis. ( Doo, G; Johnson, DS, 1999) |
| " Safety assessments included treatment-emergent adverse events (TEAEs) and posttreatment worsening of erythema (composite CEA/SSA increase of 1-grade severity from baseline; rebound effect)." | 6.87 | Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial. ( Ahluwalia, G; Berk, DR; Cook-Bolden, FE; Draelos, ZD; DuBois, J; Grande, K; Kircik, LH; Weng, E; Werschler, P, 2018) |
| "In this retrospective study, 36 patients were given oxymetazoline as a first step in treatment for posterior epistaxis." | 3.70 | Oxymetazoline in the treatment of posterior epistaxis. ( Doo, G; Johnson, DS, 1999) |
| " Safety assessments included treatment-emergent adverse events (TEAEs) and posttreatment worsening of erythema (composite CEA/SSA increase of 1-grade severity from baseline; rebound effect)." | 2.87 | Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial. ( Ahluwalia, G; Berk, DR; Cook-Bolden, FE; Draelos, ZD; DuBois, J; Grande, K; Kircik, LH; Weng, E; Werschler, P, 2018) |
| "Symptomatic relapse and recurrence were similar between groups." | 2.68 | Randomized controlled trial of 3 vs 10 days of trimethoprim/sulfamethoxazole for acute maxillary sinusitis. ( Holleman, DR; Samsa, GP; Simel, DL; Williams, JW, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kircik, LH | 1 |
| DuBois, J | 1 |
| Draelos, ZD | 1 |
| Werschler, P | 1 |
| Grande, K | 1 |
| Cook-Bolden, FE | 1 |
| Weng, E | 1 |
| Berk, DR | 1 |
| Ahluwalia, G | 1 |
| Prieto, M | 1 |
| Gómez, FM | 1 |
| Teresa Giralt, M | 1 |
| Kumar, VV | 1 |
| Gaughan, J | 1 |
| Isaacson, G | 1 |
| Szeremeta, W | 1 |
| Williams, JW | 1 |
| Holleman, DR | 1 |
| Samsa, GP | 1 |
| Simel, DL | 1 |
| Borges Dinis, P | 1 |
| Guerra, JB | 1 |
| Gomes, A | 1 |
| Doo, G | 1 |
| Johnson, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feasibility Study of a Nasal Compression Device in Comparison to Digital Nasal Compression for Stopping Epistaxis[NCT05789264] | 40 participants (Anticipated) | Interventional | 2023-09-26 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for oxymetazoline and Recrudescence
| Article | Year |
|---|---|
Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Dermatitis; Double-Blind Method; Erythema | 2018 |
Randomized controlled trial of 3 vs 10 days of trimethoprim/sulfamethoxazole for acute maxillary sinusitis.
Topics: Acute Disease; Adult; Drug Administration Schedule; Humans; Male; Maxillary Sinusitis; Middle Aged; | 1995 |
4 other studies available for oxymetazoline and Recrudescence
| Article | Year |
|---|---|
Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain.
Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Bra | 2003 |
Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction.
Topics: Administration, Topical; Adolescent; Adrenergic alpha-Agonists; Anti-Infective Agents; Antibiotic Pr | 2005 |
Sequential clinical comparison between two commercially available rhinomanometers.
Topics: Adolescent; Adult; Aged; Airway Resistance; Child; Chronic Disease; Equipment Design; Female; Humans | 1994 |
Oxymetazoline in the treatment of posterior epistaxis.
Topics: Adult; Aged; Epistaxis; Female; Humans; Male; Middle Aged; Nasal Decongestants; Oxymetazoline; Recur | 1999 |