oxymetazoline has been researched along with Pain in 7 studies
Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In untreated mice, morphine, fentanyl, clonidine, oxymetazoline, desipramine and lidocaine, but not MK801, produced dose-related antinociception when tested using a 55 degrees C water tail-flick test." | 1.31 | Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. ( Shannon, HE; Womer, DE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, AK | 3 |
| Chiu, CC | 3 |
| Zhu, GC | 3 |
| Wang, JJ | 3 |
| Chen, YW | 3 |
| Hung, CH | 3 |
| Prieto, M | 1 |
| Gómez, FM | 1 |
| Teresa Giralt, M | 1 |
| Jonas, NE | 1 |
| Visser, MF | 1 |
| Oomen, A | 1 |
| Albertyn, R | 1 |
| van Dijk, M | 1 |
| Prescott, CA | 1 |
| Noorily, AD | 1 |
| Otto, RA | 1 |
| Noorily, SH | 1 |
| Womer, DE | 1 |
| Shannon, HE | 1 |
| Baraniuk, JN | 1 |
| Ali, M | 1 |
| Naranch, K | 1 |
| Loomis, CW | 1 |
| Vyas, D | 1 |
| Sherman, SE | 1 |
2 trials available for oxymetazoline and Pain
| Article | Year |
|---|---|
Is topical local anaesthesia necessary when performing paediatric flexible nasendoscopy? A double-blind randomized controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Anxiety; Child; Double-Blind Method; Drug Combinations; | 2007 |
Intranasal anesthetic effects of lidocaine and tetracaine compared.
Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Middl | 1995 |
5 other studies available for oxymetazoline and Pain
| Article | Year |
|---|---|
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain.
Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Bra | 2003 |
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Dru | 2000 |
Hypertonic saline nasal provocation and acoustic rhinometry.
Topics: Administration, Intranasal; Dose-Response Relationship, Drug; Humans; Hypertonic Solutions; Kinetics | 2002 |
Intrathecal oxymetazoline does not produce neurotoxicity in the spinal cord of the rat.
Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; G | 1992 |