Page last updated: 2024-11-02

oxymetazoline and Pain

oxymetazoline has been researched along with Pain in 7 studies

Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"In untreated mice, morphine, fentanyl, clonidine, oxymetazoline, desipramine and lidocaine, but not MK801, produced dose-related antinociception when tested using a 55 degrees C water tail-flick test."1.31Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. ( Shannon, HE; Womer, DE, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chou, AK3
Chiu, CC3
Zhu, GC3
Wang, JJ3
Chen, YW3
Hung, CH3
Prieto, M1
Gómez, FM1
Teresa Giralt, M1
Jonas, NE1
Visser, MF1
Oomen, A1
Albertyn, R1
van Dijk, M1
Prescott, CA1
Noorily, AD1
Otto, RA1
Noorily, SH1
Womer, DE1
Shannon, HE1
Baraniuk, JN1
Ali, M1
Naranch, K1
Loomis, CW1
Vyas, D1
Sherman, SE1

Trials

2 trials available for oxymetazoline and Pain

ArticleYear
Is topical local anaesthesia necessary when performing paediatric flexible nasendoscopy? A double-blind randomized controlled trial.
    International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:11

    Topics: Administration, Topical; Anesthetics, Local; Anxiety; Child; Double-Blind Method; Drug Combinations;

2007
Intranasal anesthetic effects of lidocaine and tetracaine compared.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:4

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Middl

1995

Other Studies

5 other studies available for oxymetazoline and Pain

ArticleYear
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L

2023
Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain.
    Stress (Amsterdam, Netherlands), 2003, Volume: 6, Issue:4

    Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Bra

2003
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Dru

2000
Hypertonic saline nasal provocation and acoustic rhinometry.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:4

    Topics: Administration, Intranasal; Dose-Response Relationship, Drug; Humans; Hypertonic Solutions; Kinetics

2002
Intrathecal oxymetazoline does not produce neurotoxicity in the spinal cord of the rat.
    Brain research, 1992, Dec-18, Volume: 599, Issue:1

    Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; G

1992