oxymetazoline has been researched along with Intraocular Pressure in 6 studies
Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics in patients with open-angle glaucoma and to compare the results with those measured in healthy control participants." | 9.12 | Effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics. ( Akarsu, C; Arikan, OK; Ergin, A; Koç, C; Unal, B, 2006) |
| "To determine the effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics in patients with open-angle glaucoma and to compare the results with those measured in healthy control participants." | 5.12 | Effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics. ( Akarsu, C; Arikan, OK; Ergin, A; Koç, C; Unal, B, 2006) |
| "Two double-blind, random-assignment clinical trials demonstrated the effectiveness of topical oxymetazoline hydrochloride in reducing histamine-induced hyperemia." | 5.05 | Topically applied oxymetazoline. Ocular vasoconstrictive activity, pharmacokinetics, and metabolism. ( Anderson, J; Chen, CC; Duzman, E; Leopold, IH; Lue, JC; Vita, JB, 1983) |
| "1) Moxonidine (MOX), injected icvt into the anterior lateral ventricle of NZW rabbits, induced bilateral, ocular hypotension (> 7." | 3.69 | Potential role of imidazoline (I1) receptors in modulating aqueous humor dynamics. ( Campbell, WR; Potter, DE, 1994) |
| "Oxymetazoline, an alpha 2 agonist, was active in lowering intraocular pressure in normal and sympathetically denervated rabbit eyes." | 3.69 | Oxymetazoline: potential mechanisms of inhibitory effects on aqueous humor dynamics. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1996) |
| "Oxymetazoline reduces intraocular pressure by decreasing aqueous humor flow rates and increasing uveoscleral outflow." | 3.68 | Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits. ( Becker, B; Lee, PY; Mittag, TW; Podos, SM; Serle, JB; Taniguchi, T; Wang, RF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arikan, OK | 1 |
| Akarsu, C | 1 |
| Unal, B | 1 |
| Ergin, A | 1 |
| Koç, C | 1 |
| Duzman, E | 1 |
| Anderson, J | 1 |
| Vita, JB | 1 |
| Lue, JC | 1 |
| Chen, CC | 1 |
| Leopold, IH | 1 |
| Campbell, WR | 1 |
| Potter, DE | 2 |
| Wang, RF | 1 |
| Lee, PY | 1 |
| Taniguchi, T | 1 |
| Becker, B | 1 |
| Podos, SM | 1 |
| Serle, JB | 1 |
| Mittag, TW | 1 |
| Chu, TC | 1 |
| Ogidigben, MJ | 1 |
| Heilmann, K | 1 |
| Goebel, U | 1 |
2 trials available for oxymetazoline and Intraocular Pressure
| Article | Year |
|---|---|
Effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics.
Topics: Administration, Topical; Adolescent; Adult; Aged; Audiometry; Blood Flow Velocity; Female; Glaucoma, | 2006 |
Topically applied oxymetazoline. Ocular vasoconstrictive activity, pharmacokinetics, and metabolism.
Topics: Administration, Topical; Adult; Animals; Clinical Trials as Topic; Conjunctivitis; Dose-Response Rel | 1983 |
4 other studies available for oxymetazoline and Intraocular Pressure
| Article | Year |
|---|---|
Potential role of imidazoline (I1) receptors in modulating aqueous humor dynamics.
Topics: Administration, Topical; Animals; Aqueous Humor; Benzofurans; Brain; Catheters, Indwelling; Imidazol | 1994 |
Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits.
Topics: Animals; Aqueous Humor; Blood Flow Velocity; Disease Models, Animal; Eye; Female; Glaucoma; Intraocu | 1993 |
Oxymetazoline: potential mechanisms of inhibitory effects on aqueous humor dynamics.
Topics: Adrenergic alpha-Agonists; Animals; Aqueous Humor; Ciliary Body; Cyclic AMP; Denervation; Epithelium | 1996 |
[Effect of locally administered oxymetazoline on intraocular pressure].
Topics: Imidazoles; Intraocular Pressure; Ophthalmic Solutions; Oxymetazoline | 1975 |