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oxymetazoline and Disease Models, Animal

oxymetazoline has been researched along with Disease Models, Animal in 7 studies

Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"According to the results, xylitol solution is effective as mometasone, usable and well-priced in the treatment of rhinitis medicamentosa."7.91Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study. ( Cam, B; Gergin, O; Midi, A; Sari, M, 2019)
"When applied topically, oxymetazoline and brimonidine reduce the persistent facial erythema of rosacea; this effect is mediated by cutaneous vasoconstriction induced by postsynaptic activation of α-adrenoceptors."7.88Reduction in ultraviolet B light-induced erythema by oxymetazoline and brimonidine is mediated by different α-adrenoceptors. ( Gil, D; Hsia, E; Tian, M, 2018)
"According to the results, xylitol solution is effective as mometasone, usable and well-priced in the treatment of rhinitis medicamentosa."3.91Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study. ( Cam, B; Gergin, O; Midi, A; Sari, M, 2019)
"When applied topically, oxymetazoline and brimonidine reduce the persistent facial erythema of rosacea; this effect is mediated by cutaneous vasoconstriction induced by postsynaptic activation of α-adrenoceptors."3.88Reduction in ultraviolet B light-induced erythema by oxymetazoline and brimonidine is mediated by different α-adrenoceptors. ( Gil, D; Hsia, E; Tian, M, 2018)
"Oxymetazoline reduces intraocular pressure by decreasing aqueous humor flow rates and increasing uveoscleral outflow."3.68Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits. ( Becker, B; Lee, PY; Mittag, TW; Podos, SM; Serle, JB; Taniguchi, T; Wang, RF, 1993)
"Oxymetazoline did not cause ototoxicity in a chinchilla animal model 2 months after a single application via a tympanostomy tube."1.38Oxymetazoline ototoxicity in a chinchilla animal model. ( Akache, F; Akinpelu, OV; Daniel, SJ; Funnell, WR; Sahmkow, S, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Cam, B1
Sari, M1
Midi, A1
Gergin, O1
Hsia, E1
Tian, M1
Gil, D1
Daniel, SJ1
Akinpelu, OV1
Sahmkow, S1
Funnell, WR1
Akache, F1
Fülöp, K1
Zádori, Z1
Rónai, AZ1
Gyires, K1
Wang, RF1
Lee, PY1
Taniguchi, T1
Becker, B1
Podos, SM1
Serle, JB1
Mittag, TW1

Other Studies

7 other studies available for oxymetazoline and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019, Volume: 276, Issue:11

    Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Male; Mometas

2019
Reduction in ultraviolet B light-induced erythema by oxymetazoline and brimonidine is mediated by different α-adrenoceptors.
    Experimental dermatology, 2018, Volume: 27, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Dis

2018
Oxymetazoline ototoxicity in a chinchilla animal model.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, Volume: 146, Issue:1

    Topics: Administration, Topical; Animals; Cerebrospinal Fluid Otorrhea; Chinchilla; Disease Models, Animal;

2012
Characterisation of alpha2-adrenoceptor subtypes involved in gastric emptying, gastric motility and gastric mucosal defence.
    European journal of pharmacology, 2005, Dec-28, Volume: 528, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal;

2005
Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:4

    Topics: Animals; Aqueous Humor; Blood Flow Velocity; Disease Models, Animal; Eye; Female; Glaucoma; Intraocu

1993