Page last updated: 2024-11-02

oxymetazoline and Chronic Illness

oxymetazoline has been researched along with Chronic Illness in 10 studies

Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to summarise the evidence for efficacy of combination treatment of intranasal corticosteroid spray with oxymetazoline hydrochloride nasal spray for chronic rhinitis."9.22Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review. ( Camacho, M; Neighbors, CL; Salvador, CF; Tsai, P; Zhu, B, 2022)
"We sought to explore the benefit of oxymetazoline (Oxymet) plus INS on nasal congestion without inducing rhinitis medicamentosa."9.22The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial. ( Assanasen, P; Pradubpongsa, P; Tantilipikorn, P; Thongngarm, T, 2016)
"This study aimed to summarise the evidence for efficacy of combination treatment of intranasal corticosteroid spray with oxymetazoline hydrochloride nasal spray for chronic rhinitis."5.22Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review. ( Camacho, M; Neighbors, CL; Salvador, CF; Tsai, P; Zhu, B, 2022)
"We sought to explore the benefit of oxymetazoline (Oxymet) plus INS on nasal congestion without inducing rhinitis medicamentosa."5.22The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial. ( Assanasen, P; Pradubpongsa, P; Tantilipikorn, P; Thongngarm, T, 2016)
"Nasal obstruction is caused by rebound swelling when the decongestive effect has disappeared."1.33[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa]. ( Bloching, M; Holzhausen, HJ; Knipping, S; Riederer, A, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Neighbors, CL1
Salvador, CF1
Zhu, B1
Camacho, M1
Tsai, P1
Thongngarm, T1
Assanasen, P1
Pradubpongsa, P1
Tantilipikorn, P1
Schechtman, SA1
Wertz, AP1
Shanks, A1
Thompson, A1
Tremper, K1
Pynnonen, MA1
Healy, DW1
Prieto, M1
Gómez, FM1
Teresa Giralt, M1
Kumar, VV1
Gaughan, J1
Isaacson, G1
Szeremeta, W1
Knipping, S1
Holzhausen, HJ1
Riederer, A1
Bloching, M1
Borges Dinis, P1
Guerra, JB1
Gomes, A1
Flügge, G1
Riegle, EV1
Gunter, JB1
Lusk, RP1
Muntz, HR1
Weiss, KL1
Stride, RD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hot Saline Irrigation vs Room Temperature Saline Irrigation in the Control of Intraoperative Bleeding During Functional Endoscopic Sinus Surgery (FESS)[NCT01717274]60 participants (Actual)Interventional2012-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for oxymetazoline and Chronic Illness

ArticleYear
Intranasal corticosteroid and oxymetazoline for chronic rhinitis: a systematic review.
    The Journal of laryngology and otology, 2022, Volume: 136, Issue:1

    Topics: Administration, Intranasal; Chronic Disease; Glucocorticoids; Humans; Nasal Decongestants; Oxymetazo

2022

Trials

2 trials available for oxymetazoline and Chronic Illness

ArticleYear
The effectiveness of oxymetazoline plus intranasal steroid in the treatment of chronic rhinitis: A randomised controlled trial.
    Asian Pacific journal of allergy and immunology, 2016, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Budesonide; Chronic Disease; Double-Blind Method; Drug Therapy, C

2016
Comparison of vasoconstrictors for functional endoscopic sinus surgery in children.
    The Laryngoscope, 1992, Volume: 102, Issue:7

    Topics: Blood Pressure; Child; Child, Preschool; Chronic Disease; Cocaine; Double-Blind Method; Heart Rate;

1992

Other Studies

7 other studies available for oxymetazoline and Chronic Illness

ArticleYear
Preoperative β-blockade and hypertension in the first hour of functional endoscopic sinus surgery.
    The Laryngoscope, 2017, Volume: 127, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anesthetics, Local; Chronic Disease; Dr

2017
Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain.
    Stress (Amsterdam, Netherlands), 2003, Volume: 6, Issue:4

    Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Bra

2003
Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction.
    The Laryngoscope, 2005, Volume: 115, Issue:2

    Topics: Administration, Topical; Adolescent; Adrenergic alpha-Agonists; Anti-Infective Agents; Antibiotic Pr

2005
[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa].
    HNO, 2006, Volume: 54, Issue:10

    Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Capillary Permeability; Chronic Disease; Dose

2006
Sequential clinical comparison between two commercially available rhinomanometers.
    Acta oto-laryngologica, 1994, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Airway Resistance; Child; Chronic Disease; Equipment Design; Female; Humans

1994
Alterations in the central nervous alpha 2-adrenoceptor system under chronic psychosocial stress.
    Neuroscience, 1996, Volume: 75, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Chronic Disease; Down-Regulatio

1996
Nasal decongestant therapy.
    The British journal of clinical practice, 1967, Nov-11, Volume: 21, Issue:11

    Topics: Biopsy; Chronic Disease; Epinephrine; Humans; Imidazoles; Nasal Decongestants; Oxymetazoline; Rhinit

1967