Page last updated: 2024-11-02

oxymetazoline and Bilateral Headache

oxymetazoline has been researched along with Bilateral Headache in 3 studies

Oxymetazoline: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
oxymetazoline : A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Research Excerpts

ExcerptRelevanceReference
" Safety assessments included treatment-emergent adverse events (TEAEs) and posttreatment worsening of erythema (composite CEA/SSA increase of 1-grade severity from baseline; rebound effect)."6.87Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial. ( Ahluwalia, G; Berk, DR; Cook-Bolden, FE; Draelos, ZD; DuBois, J; Grande, K; Kircik, LH; Weng, E; Werschler, P, 2018)
"Oxymetazoline is a sympathomimetic amine found in over-the-counter nasal decongestants."5.32Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray. ( Hill, MD; Hudon, ME; Loewen, AH, 2004)
" Safety assessments included treatment-emergent adverse events (TEAEs) and posttreatment worsening of erythema (composite CEA/SSA increase of 1-grade severity from baseline; rebound effect)."2.87Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial. ( Ahluwalia, G; Berk, DR; Cook-Bolden, FE; Draelos, ZD; DuBois, J; Grande, K; Kircik, LH; Weng, E; Werschler, P, 2018)
"Oxymetazoline is a sympathomimetic amine found in over-the-counter nasal decongestants."1.32Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray. ( Hill, MD; Hudon, ME; Loewen, AH, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kircik, LH1
DuBois, J1
Draelos, ZD1
Werschler, P1
Grande, K1
Cook-Bolden, FE1
Weng, E1
Berk, DR1
Ahluwalia, G1
Loewen, AH1
Hudon, ME1
Hill, MD1
Greene, RR1

Trials

1 trial available for oxymetazoline and Bilateral Headache

ArticleYear
Pivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial.
    Journal of drugs in dermatology : JDD, 2018, Jan-01, Volume: 17, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Dermatitis; Double-Blind Method; Erythema

2018

Other Studies

2 other studies available for oxymetazoline and Bilateral Headache

ArticleYear
Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Sep-14, Volume: 171, Issue:6

    Topics: Administration, Intranasal; Adult; Brain; Drug Administration Schedule; Female; Headache; Humans; Na

2004
Clinical images: Afrin-induced central nervous system vasospasm and thunderclap headache.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:10

    Topics: Cerebral Angiography; Female; Headache; Humans; Middle Aged; Nasal Decongestants; Oxymetazoline; Vas

2005