Page last updated: 2024-09-02

oxymatrine and Liver Cirrhosis

oxymatrine has been researched along with Liver Cirrhosis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (47.37)29.6817
2010's7 (36.84)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
He, C; Wang, J; Wang, W; Wang, Y; Wei, G; Wei, Y; Zhang, Z1
Huang, Z; Ji, L; Lu, B; Wei, M; Zhang, S; Zhao, Q1
Liu, X; Wang, D; Wu, X; Yang, W1
Huang, C; Jiang, X; Liu, B; Liu, H; Liu, Y; Xie, L; Zheng, L1
Chen, J; Dai, G; Hou, Y; Ji, G; Liu, Y; Song, Z; Yang, J; Zhang, Y1
Chen, J; Chen, WG; Hu, ZP; Huang, YJ; Jiang, LP; Lin, H; Wang, GL; Wen, JB; Zhou, SF; Zhou, ZW; Zhu, FQ1
Chen, XL; Deng, ZY; Jin, Y; Li, J; Lü, XW1
Liang, JX; Qu, XF; Wei, JJ; Zeng, WT; Zhang, H; Zhu, KL1
Hu, YY1
He, Y; Jian, YC; Jiang, M; Li, W; Liu, YB; Xiong, WJ1
Cai, CH; Chai, NL; Fu, Q; Shi, H; Wan, J; Wu, BY; Xu, SP1
Chen, CW; Fan, Z; Jia, Y; Lu, L; Mao, Y; Peng, YS; Song, Y; Yang, W; Zeng, M; Zhu, HY1
Song, J; Wang, LL; Yao, P; Zhong, HM; Zhu, L1
Cai, X; Chen, CW; Chen, WX; Fu, QC; Li, CZ; Lu, LG; Mao, YM; She, WM; Tang, MF; Wan, MB; Wang, H; Wang, JY; Wu, SM; Ye, J; Zeng, MD; Zhang, HQ; Zhou, XQ; Zhu, JS1
Jin, YR; Li, CH; Piao, DM; Piao, XX; Wu, CS1
Li, Q; Shi, GF1
He, JF; Liu, J; Shi, BN1
Jiang, MD; Qin, JP; Wu, XL; Xu, H; Zeng, WZ1
Shen, BS; Song, XW1

Reviews

1 review(s) available for oxymatrine and Liver Cirrhosis

ArticleYear
Pay attention to the study on active antiliver fibrosis components of Chinese herbal medicine.
    Chinese journal of integrative medicine, 2012, Volume: 18, Issue:8

    Topics: Alkaloids; Animals; Attention; Benzofurans; Drugs, Chinese Herbal; Humans; Liver Cirrhosis; Quinolizines

2012

Trials

3 trial(s) available for oxymatrine and Liver Cirrhosis

ArticleYear
[Mechanism of oxymatrine in preventing hepatic fibrosis formation in patients with chronic hepatitis B].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:8

    Topics: Adult; Alkaloids; Female; Hepatitis B, Chronic; Humans; Interleukin-10; Liver Cirrhosis; Male; Middle Aged; Quinolizines; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2010
Capsule oxymatrine in treatment of hepatic fibrosis due to chronic viral hepatitis: a randomized, double blind, placebo-controlled, multicenter clinical study.
    World journal of gastroenterology, 2004, Nov-15, Volume: 10, Issue:22

    Topics: Administration, Oral; Adolescent; Adult; Aged; Alkaloids; Antiviral Agents; Biomarkers; Capsules; Chronic Disease; Double-Blind Method; Female; Hepatitis, Viral, Human; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Placebos; Quinolizines; Treatment Outcome

2004
[Effects of oxymatrine on serum cytokines and hepatic fibrotic indexes in patients with chronic hepatitis B].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2008, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Alkaloids; Antiviral Agents; Cytokines; Female; Hepatitis B, Chronic; Humans; Interleukin-6; Liver Cirrhosis; Male; Middle Aged; Quinolizines; Transforming Growth Factor beta1; Treatment Outcome

2008

Other Studies

15 other study(ies) available for oxymatrine and Liver Cirrhosis

ArticleYear
Sodium alginate combined with oxymatrine ameliorates CCl
    International immunopharmacology, 2023, Volume: 125, Issue:Pt A

    Topics: Alginates; Alkaloids; Animals; Carbon Tetrachloride; Liver; Liver Cirrhosis; Mice; Rats; Rats, Sprague-Dawley

2023
The water extract of Sophorae tonkinensis Radix et Rhizoma alleviates non-alcoholic fatty liver disease and its mechanism.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 77

    Topics: Alanine Transaminase; Alkaloids; Animals; Cell Line; Diet; Drugs, Chinese Herbal; Fatty Acids, Nonesterified; Humans; Liver Cirrhosis; Male; Matrines; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Plant Extracts; Quinolizines; Sophora; Triglycerides; Water

2020
Oxymatrine exerts anti-fibrotic effects in a rat model of hepatic fibrosis by suppressing endoplasmic reticulum stress.
    The Journal of international medical research, 2020, Volume: 48, Issue:10

    Topics: Alkaloids; Animals; Apoptosis; Endoplasmic Reticulum Stress; Fibrosis; Liver Cirrhosis; Quinolizines; Rats

2020
Oral oxymatrine for hepatitis B cirrhosis: A systematic review protocol.
    Medicine, 2018, Volume: 97, Issue:49

    Topics: Administration, Oral; Alkaloids; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Meta-Analysis as Topic; Protective Agents; Quinolizines; Systematic Reviews as Topic

2018
Targeted delivery of the RGD-labeled biodegradable polymersomes loaded with the hydrophilic drug oxymatrine on cultured hepatic stellate cells and liver fibrosis in rats.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: Actins; Alkaloids; Animals; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Drug Carriers; Gene Expression; Hepatic Stellate Cells; Hydrophobic and Hydrophilic Interactions; Lactones; Liver; Liver Cirrhosis; Male; Maleimides; Nanostructures; Oligopeptides; Polyesters; Polyethylene Glycols; Quinolizines; Rats; Rats, Wistar

2014
Oxymatrine improves intestinal epithelial barrier function involving NF-κB-mediated signaling pathway in CCl4-induced cirrhotic rats.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Alkaloids; Animals; Carbon Tetrachloride; Endotoxins; Enzyme-Linked Immunosorbent Assay; Gene Expression; Immunohistochemistry; Interleukin-6; Intestinal Mucosa; Intestines; Liver Cirrhosis; Male; Protective Agents; Quinolizines; Random Allocation; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2014
Effect of oxymatrine on the p38 mitogen-activated protein kinases signalling pathway in rats with CCl4 induced hepatic fibrosis.
    Chinese medical journal, 2009, Jun-20, Volume: 122, Issue:12

    Topics: Actins; Alkaloids; Animals; Anti-Arrhythmia Agents; Carbon Tetrachloride; Collagen; Collagen Type IV; Hyaluronic Acid; Hydroxyproline; Laminin; Liver Cirrhosis; Male; p38 Mitogen-Activated Protein Kinases; Procollagen; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction

2009
Effect of oxymatrine on hepatic gene expression profile in experimental liver fibrosis of rats.
    Chinese journal of integrative medicine, 2012, Volume: 18, Issue:6

    Topics: Alkaloids; Animals; Down-Regulation; Liver; Liver Cirrhosis; Liver Function Tests; Male; Oligonucleotide Array Sequence Analysis; Quinolizines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Transcriptome; Up-Regulation

2012
Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells.
    World journal of gastroenterology, 2012, Aug-21, Volume: 18, Issue:31

    Topics: Alkaline Phosphatase; Alkaloids; Animals; Apoptosis; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Disease Models, Animal; Hepatic Stellate Cells; In Vitro Techniques; Liposomes; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Quinolizines; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1

2012
[Prophylactic and therapeutic effect of oxymatrine on D-galactosamine-induced rat liver fibrosis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:3

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Calcium Hydroxide; Chemoprevention; Disease Models, Animal; Galactosamine; Liver Cirrhosis; Liver Function Tests; Male; Quinolizines; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Transforming Growth Factor beta

2002
[Effects of oxymatrine on procollagen metabolism and its gene expression in experimental fibrotic rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2003, Volume: 11, Issue:11

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Collagen Type III; Disease Models, Animal; Female; Gene Expression; Liver Cirrhosis; Liver Cirrhosis, Experimental; Procollagen; Quinolizines; Rats; Rats, Sprague-Dawley

2003
Treatment of pig serum-induced rat liver fibrosis with Boschniakia rossica, oxymatrine and interferon-alpha.
    World journal of gastroenterology, 2005, Jan-07, Volume: 11, Issue:1

    Topics: Alkaloids; Animals; Antiviral Agents; Biomarkers; Blood Proteins; Disease Models, Animal; Drugs, Chinese Herbal; Immunohistochemistry; Interferon-alpha; Liver Cirrhosis; Male; Organ Size; Orobanchaceae; Quinolizines; Rats; Rats, Wistar; RNA, Messenger; Swine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Effects of oxymatrine on experimental hepatic fibrosis and its mechanism in vivo.
    World journal of gastroenterology, 2005, Jan-14, Volume: 11, Issue:2

    Topics: Alkaloids; Animals; Carbon Tetrachloride Poisoning; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Liver Cirrhosis; Male; Quinolizines; Rats; Rats, Sprague-Dawley

2005
[Effect of oxymatrine on serum matrix metalloproteinase-2 and its inhibitor in patients with chronic hepatitis B and liver cirrhosis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:11

    Topics: Adolescent; Adult; Aged; Alkaloids; Collagen Type IV; Female; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Laminin; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Middle Aged; Quinolizines; Sophora; Tissue Inhibitor of Metalloproteinase-2

2005
Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl4-induced hepatic fibrosis.
    World journal of gastroenterology, 2008, Apr-07, Volume: 14, Issue:13

    Topics: Alkaloids; Animals; Antiviral Agents; Carbon Tetrachloride; CREB-Binding Protein; Liver Cirrhosis; Male; Models, Biological; Quinolizines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Smad Proteins; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta

2008