Page last updated: 2024-09-02

oxymatrine and Innate Inflammatory Response

oxymatrine has been researched along with Innate Inflammatory Response in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's8 (53.33)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Li, F; Li, J; Liang, J; Liu, J; Luo, Y; Sun, H; Sun, K; Yuan, W; Zeng, M; Zheng, H; Zhou, H1
Jin, Y; Liu, D; Xia, W; Zhang, P; Zhou, K; Zhou, Z1
Chen, Y; Lan, X; Liu, Y; Xu, F; Zhang, Y; Zhao, J1
Chen, Q; Chen, R; Guan, B; Liu, N; Zhong, M1
Ding, J; Ding, Y; Fang, H; Pei, Y; Tan, S; Wang, H; Wei, K; Zhang, C; Zhang, W; Zou, C1
Cao, XK; Dong, PL; Han, H; Li, Z; Teng, CL; Yin, X1
Chang, B; Huang, M; Huang, W; Liang, J; Liu, Y; Long, Y; Lu, Y; Ma, W; Tai, W1
Cui, HL; Fu, Y; Li, CZ; Li, YY; Wu, HQ1
Gao, Q; Shi, HJ; Si, JW; Song, HB; Zou, Q1
Cao, Y; Cong, Y; Liu, Z; Wei, Z; Yang, Z; Yin, R; Zhang, N; Zhou, E1
Qin, XY; Shi, L; Wang, HW; Wang, QZ; Xu, YP1
He, D; Huang, XM; Li, HB; Nie, XZ; Xie, LQ; Zhang, Y; Zheng, WB; Zhou, WX1
Dong, XQ; Hu, YY; Huang, M; Yu, WH; Zhang, ZY1
Du, D; Hu, Z; Liu, Z; Wang, Y; Xu, M; Yuan, X1

Reviews

1 review(s) available for oxymatrine and Innate Inflammatory Response

ArticleYear
Oxymatrine exerts organ- and tissue-protective effects by regulating inflammation, oxidative stress, apoptosis, and fibrosis: From bench to bedside.
    Pharmacological research, 2020, Volume: 151

    Topics: Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Apoptosis; Fibrosis; Humans; Inflammation; Oxidative Stress; Protective Agents; Quinolizines; Sophora

2020

Trials

1 trial(s) available for oxymatrine and Innate Inflammatory Response

ArticleYear
[Effects of oxymatrine on microinflammatory state in patients undergoing continuous hemodialysis: a randomized controlled trial].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2009, Volume: 7, Issue:8

    Topics: Adult; Aged; Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Female; Humans; Inflammation; Interleukin-1beta; Kidney Failure, Chronic; Male; Middle Aged; Quinolizines; Renal Dialysis; Tumor Necrosis Factor-alpha; Young Adult

2009

Other Studies

13 other study(ies) available for oxymatrine and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Oxymatrine ameliorates white matter injury by modulating gut microbiota after intracerebral hemorrhage in mice.
    CNS neuroscience & therapeutics, 2023, Volume: 29 Suppl 1

    Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Dysbiosis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Inflammation; Mice; White Matter

2023
Oxymatrine ameliorates osteoarthritis via the Nrf2/NF-κB axis in vitro and in vivo.
    Chemico-biological interactions, 2023, Aug-01, Volume: 380

    Topics: Animals; Cells, Cultured; Chondrocytes; Cytokines; Inflammation; Interleukin-1beta; Mice; NF-E2-Related Factor 2; NF-kappa B; Osteoarthritis; Signal Transduction

2023
Protective effect of Oxymatrine against acute spinal cord injury in rats via modulating oxidative stress, inflammation and apoptosis.
    Metabolic brain disease, 2020, Volume: 35, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Male; Neuroprotective Agents; Oxidative Stress; Quinolizines; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2020
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Alkaloids; Animals; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Inflammation; Intervertebral Disc Degeneration; Liposomes; Mice; Mice, Inbred Strains; Molecular Structure; Particle Size; Quinolizines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Surface Properties

2020
Synthesis and evolution of neuroprotective effects of oxymatrine derivatives as anti-Alzheimer's disease agents.
    Chemical biology & drug design, 2021, Volume: 98, Issue:1

    Topics: Alkaloids; Alzheimer Disease; Animals; Cell Survival; Drug Discovery; Humans; Inflammation; Interleukin-1beta; Microglia; Neurons; Neuroprotective Agents; PC12 Cells; Quinolizines; Rats; Small Molecule Libraries; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2021
Oxymatrine prevents synovial inflammation and migration via blocking NF-κB activation in rheumatoid fibroblast-like synoviocytes.
    International immunopharmacology, 2018, Volume: 55

    Topics: Adult; Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Movement; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Female; Fibroblasts; Humans; Inflammation; Interleukin-6; Interleukin-8; Male; Mice; Mice, Inbred DBA; Middle Aged; NF-kappa B; Quinolizines; Signal Transduction; Sophora; Synovial Membrane; Transcriptional Activation

2018
Gastroprotective and anti-ulcer effects of oxymatrine against several gastric ulcer models in rats: Possible roles of antioxidant, antiinflammatory, and prosurvival mechanisms.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:10

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Apoptosis; Catalase; Cell Line; Dinoprostone; Ethanol; Gastric Mucosa; Humans; Indomethacin; Inflammation; Interleukins; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2018
Combination of oxymatrine and diammonium glycyrrhizinate significantly mitigates mice allergic contact dermatitis induced by dinitrofluorobenzene.
    Experimental biology and medicine (Maywood, N.J.), 2019, Volume: 244, Issue:13

    Topics: Alkaloids; Animals; Creatinine; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Drug Therapy, Combination; Ear; Glycyrrhizic Acid; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-4; Male; Mice, Inbred BALB C; Mice, Inbred ICR; Potassium; Quinolizines; Skin; Sodium; Urea

2019
Oxymatrine lightened the inflammatory response of LPS-induced mastitis in mice through affecting NF-κB and MAPKs signaling pathways.
    Inflammation, 2014, Volume: 37, Issue:6

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Female; Inflammation; Inflammation Mediators; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mastitis; Mice; Mice, Inbred BALB C; NF-kappa B; Quinolizines; Signal Transduction; Sophora

2014
Oxymatrine inhibits renal fibrosis of obstructive nephropathy by downregulating the TGF-β1-Smad3 pathway.
    Renal failure, 2016, Volume: 38, Issue:6

    Topics: Acute Kidney Injury; Alkaloids; Animals; Cytokines; Disease Models, Animal; Down-Regulation; Fibrosis; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Quinolizines; Random Allocation; Signal Transduction; Smad3 Protein; Transcription Factor RelA; Transforming Growth Factor beta1; Ureteral Obstruction

2016
Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:6

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Brain Injuries; Gene Expression; Inflammation; Interleukin-1beta; Interleukin-6; Male; Neurons; NF-kappa B; Quinolizines; Rats; Rats, Wistar; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2011
The effects of the combination of sodium ferulate and oxymatrine on lipopolysaccharide-induced acute lung injury in mice.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Acute Lung Injury; Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; C-Reactive Protein; Coumaric Acids; Disease Models, Animal; Drug Combinations; Edema; Inflammation; Lipopolysaccharides; Lung; Mice; Peroxidase; Quinolizines; Random Allocation; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2012