Page last updated: 2024-09-02

oxymatrine and Chemical and Drug Induced Liver Injury

oxymatrine has been researched along with Chemical and Drug Induced Liver Injury in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, S; Jin, S; Liu, M; Yan, H1
Chen, C; Lei, L; Li, C; Li, Z; Ren, W; Su, Y; Xu, J; Yang, C1
Bao, YQ; Gu, LL; Li, YL; Lu, H; Shen, ZL1
Liu, Z; Miao, N; Pei, X; Sun, M; Wang, W; Xu, M; Zhang, C1
Du, GH; Gu, LL; Hou, BY; Lu, H; Zhang, L1
Bai, ZF; Chai, X; Cui, HR; Li, GQ; Li, RS; Liu, HM; Meng, YK; Wang, HB; Wang, JB; Xiao, XH; Zhang, ZF; Zhao, HW1
Fan, L; Feng, H; Jia, B; Lan, F; Li, L; Liu, Q; Wang, T; Wang, Y; Xiao, W; Xing, G; Ye, W; Yue, X; Zhao, L; Zhou, C1

Other Studies

7 other study(ies) available for oxymatrine and Chemical and Drug Induced Liver Injury

ArticleYear
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jun-15, Volume: 104

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Liberation; Kidney; Liposomes; Liver; Male; Matrines; Mice; Myocardium; Phosphatidylcholines; Protective Agents; Quinolizines; Spleen; Tissue Distribution

2017
Protective effects of oxymatrine against lipopolysaccharide/D‑galactosamine‑induced acute liver failure through oxidative damage, via activation of Nrf2/HO‑1 and modulation of inflammatory TLR4‑signaling pathways.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Galactosamine; Gene Expression; Glutathione Peroxidase; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Membrane Proteins; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quinolizines; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2018
Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells.
    Molecules and cells, 2018, May-31, Volume: 41, Issue:5

    Topics: Acetylcysteine; Alkaloids; Amino Acid Chloromethyl Ketones; Anthracenes; Antioxidants; Antiviral Agents; Apoptosis; Butylamines; Cell Line; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Free Radical Scavengers; Gene Expression Regulation; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Quinolizines; Reactive Oxygen Species

2018
The protective effects of the combination of sodium ferulate and oxymatrine on ethanol-induced liver damage in mice.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:1

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Coumaric Acids; Drug Therapy, Combination; Ethanol; Interleukin-6; Liver; Male; Malondialdehyde; Mice; NF-kappa B; Protective Agents; Quinolizines; Superoxide Dismutase

2014
Oxymatrine Induces Liver Injury through JNK Signalling Pathway Mediated by TNF-α In Vivo.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:4

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Antiviral Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Liver; Male; MAP Kinase Signaling System; Mice, Inbred ICR; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Quinolizines; Random Allocation; Receptors, Tumor Necrosis Factor, Type I; TNF Receptor-Associated Death Domain Protein; Tumor Necrosis Factor-alpha

2016
Oxymatrine attenuates CCl4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-β1 signaling pathways.
    International immunopharmacology, 2016, Volume: 36

    Topics: Alanine Transaminase; Alkaloids; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Cytokines; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Macrophages; Male; Membrane Proteins; Mice; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta1

2016
Protective effects of oxymatrine against arsenic trioxide-induced liver injury.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Alkaloids; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Heme Oxygenase-1; Male; NF-E2-Related Factor 2; Oxidative Stress; Oxides; Quinolizines; Rats; Rats, Wistar; Signal Transduction

2017