Page last updated: 2024-09-02

oxymatrine and Cerebral Ischemia

oxymatrine has been researched along with Cerebral Ischemia in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Jianqiang, Y; Lin, M; Ning, J; Ningtian, M; Qingluan, Z; Ru, Z; Rui, C; Tao, S; Yinju, H; Yuxiang, L1
Du, J; Hao, YJ; Jin, SJ; Lei, Z; Li, J; Li, YX; Sun, T; Wang, J; Wang, SJ; Wang, TF; Wang, YS; Yu, JQ; Zhou, R1
Du, J; Hao, YJ; Li, YX; Ma, L; Sun, T; Wang, HB; Wang, J; Wang, SJ; Wang, YS; Yu, JQ; Zhao, P; Zhou, R1
He, MT; Jing, L; Ma, YM; Wang, R; Wang, WJ; Zhang, DH; Zhang, JZ1
Jiao-Yan, Y; Mei, Z; Na, H; Peng, Y; Qi, Y; Qing-Qing, L; Rui-Tao, Z; Ting, S; Wei, J; Xi, L1
Chu, X; Kong, Q; Qiao, B; Zhou, S1
Fan, H; Li, L; Liu, Y; Yang, C; Yang, Y; Yin, J; Zhang, X1
Cui, L; Du, W; Li, M; Liu, L; Wang, L; Yang, R; Zhang, X1
Feng, B; Gerile, O; Guo, YY; Li, XB; Li, YJ; Liu, SB; Yang, L; Yang, Q; Zhang, K; Zhang, N; Zhao, MG1

Other Studies

9 other study(ies) available for oxymatrine and Cerebral Ischemia

ArticleYear
Anti-apoptotic and neuroprotective effects of oxysophoridine on cerebral ischemia both in vivo and in vitro.
    Planta medica, 2013, Volume: 79, Issue:11

    Topics: Alkaloids; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Brain Ischemia; Caspase 3; Cytochromes c; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms

2013
Oxysophoridine protects against focal cerebral ischemic injury by inhibiting oxidative stress and apoptosis in mice.
    Neurochemical research, 2013, Volume: 38, Issue:11

    Topics: Alkaloids; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Reperfusion Injury

2013
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
    Inflammation, 2015, Volume: 38, Issue:6

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Brain; Brain Ischemia; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Intercellular Adhesion Molecule-1; Male; Mice, Inbred ICR; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Reperfusion Injury; Signal Transduction; Time Factors; Transcription Factor RelA

2015
Oxymatrine Alleviates Hyperglycemic Cerebral Ischemia/Reperfusion Injury via Protecting Microvessel.
    Neurochemical research, 2022, Volume: 47, Issue:5

    Topics: Alkaloids; Animals; Apoptosis; Brain Ischemia; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Microvessels; Quinolizines; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2022
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 84

    Topics: Alkaloids; Animals; Blood-Brain Barrier; Brain Ischemia; Caveolin 1; Disease Models, Animal; Down-Regulation; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Neuroprotective Agents; Permeability; Quinolizines; Reperfusion Injury; Sophora

2021
Oxymatrine attenuates cognitive deficits through SIRT1-mediated autophagy in ischemic stroke.
    Journal of neuroimmunology, 2018, 10-15, Volume: 323

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Autophagy; Brain Ischemia; Cognitive Dysfunction; Male; Quinolizines; Random Allocation; Rats; Rats, Sprague-Dawley; Sirtuin 1; Stroke

2018
Oxymatrine downregulates TLR4, TLR2, MyD88, and NF-kappaB and protects rat brains against focal ischemia.
    Mediators of inflammation, 2009, Volume: 2009

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Molecular Structure; Myeloid Differentiation Factor 88; Neuroprotective Agents; NF-kappa B; Quinolizines; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4

2009
The neuroprotection of oxymatrine in cerebral ischemia/reperfusion is related to nuclear factor erythroid 2-related factor 2 (nrf2)-mediated antioxidant response: role of nrf2 and hemeoxygenase-1 expression.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:5

    Topics: Alkaloids; Animals; Antioxidants; Blotting, Western; Brain Ischemia; Heme Oxygenase-1; Immunohistochemistry; Neuroprotective Agents; NF-E2-Related Factor 2; Quinolizines; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2011
Neuroprotective effects of oxymatrine against excitotoxicity partially through down-regulation of NR2B-containing NMDA receptors.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Feb-15, Volume: 20, Issue:3-4

    Topics: Alkaloids; Animals; bcl-2-Associated X Protein; Brain Ischemia; Calcium; Cell Survival; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Male; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Quinolizines; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Sophora

2013