Page last updated: 2024-09-02

oxymatrine and Alzheimer Disease

oxymatrine has been researched along with Alzheimer Disease in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Chen, R; Sun, J; Tian, J; Wang, Z; Zhao, Y; Zhi, Z1
Gao, C; Sui, R; Wang, Z; Zhang, L; Zhu, Y1
Cao, XK; Dong, PL; Han, H; Li, Z; Teng, CL; Yin, X1
Dong, P; Han, H; Han, W; Ji, X1
Chen, Y; Hao, Y; Li, H; Lv, Z; Qi, Z; Qiao, B1

Other Studies

5 other study(ies) available for oxymatrine and Alzheimer Disease

ArticleYear
Targeting the TLR4/NF-κB pathway in β-amyloid-stimulated microglial cells: A possible mechanism that oxysophoridine exerts anti-oxidative and anti-inflammatory effects in an in vitro model of Alzheimer's disease.
    Brain research bulletin, 2021, Volume: 175

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Interleukin-1beta; Mice; Microglia; NF-kappa B; Oxidative Stress; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2021
Oxymatrine-mediated prevention of amyloid β-peptide-induced apoptosis on Alzheimer's model PC12 cells: in vitro cell culture studies and in vivo cognitive assessment in rats.
    Inflammopharmacology, 2023, Volume: 31, Issue:5

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Culture Techniques; Cognition; Humans; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Rats

2023
Synthesis and evolution of neuroprotective effects of oxymatrine derivatives as anti-Alzheimer's disease agents.
    Chemical biology & drug design, 2021, Volume: 98, Issue:1

    Topics: Alkaloids; Alzheimer Disease; Animals; Cell Survival; Drug Discovery; Humans; Inflammation; Interleukin-1beta; Microglia; Neurons; Neuroprotective Agents; PC12 Cells; Quinolizines; Rats; Small Molecule Libraries; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2021
Oxymatrine attenuates amyloid beta 42 (Aβ
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:2

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Male; Maze Learning; Memory; Neurons; Oxidative Stress; Peptide Fragments; Primary Cell Culture; Quinolizines; Rats; Rats, Sprague-Dawley

2019
Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation.
    Journal of neuroimmunology, 2019, 09-15, Volume: 334

    Topics: Alkaloids; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Inflammation Mediators; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolizines

2019