Page last updated: 2024-09-02

oxymatrine and Acute Liver Injury, Drug-Induced

oxymatrine has been researched along with Acute Liver Injury, Drug-Induced in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, S; Jin, S; Liu, M; Yan, H1
Chen, C; Lei, L; Li, C; Li, Z; Ren, W; Su, Y; Xu, J; Yang, C1
Bao, YQ; Gu, LL; Li, YL; Lu, H; Shen, ZL1
Liu, Z; Miao, N; Pei, X; Sun, M; Wang, W; Xu, M; Zhang, C1
Du, GH; Gu, LL; Hou, BY; Lu, H; Zhang, L1
Bai, ZF; Chai, X; Cui, HR; Li, GQ; Li, RS; Liu, HM; Meng, YK; Wang, HB; Wang, JB; Xiao, XH; Zhang, ZF; Zhao, HW1
Fan, L; Feng, H; Jia, B; Lan, F; Li, L; Liu, Q; Wang, T; Wang, Y; Xiao, W; Xing, G; Ye, W; Yue, X; Zhao, L; Zhou, C1

Other Studies

7 other study(ies) available for oxymatrine and Acute Liver Injury, Drug-Induced

ArticleYear
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jun-15, Volume: 104

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Liberation; Kidney; Liposomes; Liver; Male; Matrines; Mice; Myocardium; Phosphatidylcholines; Protective Agents; Quinolizines; Spleen; Tissue Distribution

2017
Protective effects of oxymatrine against lipopolysaccharide/D‑galactosamine‑induced acute liver failure through oxidative damage, via activation of Nrf2/HO‑1 and modulation of inflammatory TLR4‑signaling pathways.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Galactosamine; Gene Expression; Glutathione Peroxidase; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Membrane Proteins; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quinolizines; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2018
Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells.
    Molecules and cells, 2018, May-31, Volume: 41, Issue:5

    Topics: Acetylcysteine; Alkaloids; Amino Acid Chloromethyl Ketones; Anthracenes; Antioxidants; Antiviral Agents; Apoptosis; Butylamines; Cell Line; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Free Radical Scavengers; Gene Expression Regulation; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Quinolizines; Reactive Oxygen Species

2018
The protective effects of the combination of sodium ferulate and oxymatrine on ethanol-induced liver damage in mice.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:1

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Coumaric Acids; Drug Therapy, Combination; Ethanol; Interleukin-6; Liver; Male; Malondialdehyde; Mice; NF-kappa B; Protective Agents; Quinolizines; Superoxide Dismutase

2014
Oxymatrine Induces Liver Injury through JNK Signalling Pathway Mediated by TNF-α In Vivo.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:4

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Antiviral Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Liver; Male; MAP Kinase Signaling System; Mice, Inbred ICR; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Quinolizines; Random Allocation; Receptors, Tumor Necrosis Factor, Type I; TNF Receptor-Associated Death Domain Protein; Tumor Necrosis Factor-alpha

2016
Oxymatrine attenuates CCl4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-β1 signaling pathways.
    International immunopharmacology, 2016, Volume: 36

    Topics: Alanine Transaminase; Alkaloids; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Cytokines; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Macrophages; Male; Membrane Proteins; Mice; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta1

2016
Protective effects of oxymatrine against arsenic trioxide-induced liver injury.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Alkaloids; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Heme Oxygenase-1; Male; NF-E2-Related Factor 2; Oxidative Stress; Oxides; Quinolizines; Rats; Rats, Wistar; Signal Transduction

2017