oxyfedrine and Tuberculosis--Pulmonary

In 34 patients with chronic cor pulmonale, the drugs from a group of beta-adrenostimulants, nonachlazinum and oxyphedrinum, were tested for effects on their hemodynamics, pulmonary ventilation function, blood gas composition and acid-base balance. In patients with circulatory failure due to lung diseases, nonachlazinum and oxyphedrinum were found to exert a pronounced positive intropic action, to contribute to an increase in cardiac output. The agents may be included into the multimodality therapy of patients with decompensated chronic cor pulmonale.

Topics: Adolescent; Adult; Aged; Bronchitis; Chronic Disease; Clinical Trials as Topic; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nonachlazine; Oxyfedrine; Phenothiazines; Propiophenones; Respiration; Tuberculosis, Pulmonary

The authors have analyzed their experience in the diagnosis and treatment of 32 patients with broncholiths-induced obturation of the segmentary and lobar bronchi with subsequent prolonged recurring inflammatory, cirrhotic or suppurative bronchopulmonary processes farther to a site of bronchial obstruction. 37% of the patients only knew of primary tuberculosis. Chest pains were noted in 50%, hemoptysis in 40%. The rest of the symptoms were not characteristic. Therefore true diagnosis was established, as a rule, in a late period. Patients with broncholiths were treated for many years with the diagnosis of recurring pneumonia, cirrhotic or suppurative processes. Bronchoscopy is a method of choice because broncholiths can be found in a visible zone of the bronchial tree. The earlier bronchoscopy is performed, the easier and better can be the patients' cure.

Topics: Adult; Aged; Bronchial Diseases; Calculi; Female; Humans; Male; Middle Aged; Oxyfedrine; Pneumonia; Propiophenones; Recurrence; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary