oxyfedrine and Chronic-Disease

Topics: Amiodarone; Angina Pectoris; Chronic Disease; Coronary Disease; Digitalis Glycosides; Humans; Lidoflazine; Oxyfedrine; Perhexiline; Practolol; Prenylamine; Verapamil

Composite preparation refracterin administered in a dose of 300 mg/day for 3 days in addition to routine therapy significantly improved the results of treatment of severe cardiac insufficiency of ischemic genesis compared to placebo. Improvement of clinical status of patients is determined by positive dynamics of systolic and diastolic functions of the left ventricle.

Topics: Acetyldigoxins; Aged; Cardiac Output, Low; Cardiotonic Agents; Chronic Disease; Coronary Disease; Cytochromes c; Drug Combinations; Echocardiography; Female; Humans; Inosine; Male; Middle Aged; NAD; Oxyfedrine; Systole; Treatment Outcome; Ventricular Function, Left

In 34 patients with chronic cor pulmonale, the drugs from a group of beta-adrenostimulants, nonachlazinum and oxyphedrinum, were tested for effects on their hemodynamics, pulmonary ventilation function, blood gas composition and acid-base balance. In patients with circulatory failure due to lung diseases, nonachlazinum and oxyphedrinum were found to exert a pronounced positive intropic action, to contribute to an increase in cardiac output. The agents may be included into the multimodality therapy of patients with decompensated chronic cor pulmonale.

Topics: Adolescent; Adult; Aged; Bronchitis; Chronic Disease; Clinical Trials as Topic; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nonachlazine; Oxyfedrine; Phenothiazines; Propiophenones; Respiration; Tuberculosis, Pulmonary

Topics: Blood Pressure; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Heart Rate; Humans; Oxyfedrine; Propiophenones; Pulse; Respiration

Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Biopsy; Cardiomyopathies; Chronic Disease; Cytochrome c Group; Drug Combinations; Female; Heart Failure; Humans; Inosine; Male; Middle Aged; NAD; Oxyfedrine; Treatment Outcome

Ildamen has a positive effect on the course of psoriasis in patients with cardiovascular diseases. Its effect in psoriasis appears to be explained by its stimulating action on skin beta-adrenoreceptors. The study carried out by the authors confirms the contribution of beta-adrenoreceptors to the pathogenesis of psoriasis.

Topics: Adult; Aged; Cardiovascular Diseases; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Oxyfedrine; Psoriasis; Receptors, Adrenergic, beta; Recurrence; Time Factors

The experiments on dogs showed that in chronic myocardial ischaemia nonachlasine raising the retrograde arterial pressure and increasing the retrograde blood inflow to the ischaemic focus exerts a positive influence on the collateral cardiac haemodynamics. Raising the tonus of the coronary vessels in the intact regions of the myocardium to a greater extent than in the ischaemic region, nonachlasine redistributes the bloodflow to the advantage of the ischaemic zone. Oxyphedrin, decreasing of the ischaemic zone. Oxyphedrin, decreasing the tonus of the coronaries, especially in the intact areas of the myocardium, elicits the syndrome of "stealing" the zone of ischaemia.

Topics: Adrenergic beta-Agonists; Angina Pectoris; Animals; Chronic Disease; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Nonachlazine; Oxyfedrine; Regional Blood Flow; Vasodilator Agents

Topics: Adrenergic beta-Antagonists; Bradycardia; Chronic Disease; Coronary Disease; Humans; Nitroglycerin; Oxyfedrine

In feline experiments and 65 clinical cases of ischaemic heart disease the efficacy of a new beta-stimulating agetn -- Ildamen -- was studied, the obtained effect was compared to that of Euphillin. Ildamen was found to be highly effective in patients with a moderately decreased coronary reserve and without atherosclerotic lesions in the coronary vessels.

Topics: Adrenergic beta-Agonists; Adult; Aged; Aminophylline; Animals; Blood Pressure; Cats; Chronic Disease; Coronary Circulation; Coronary Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Oxyfedrine; Propiophenones; Vasodilator Agents