oxycodone and Colonic Inertia

oxycodone has been researched along with Colonic Inertia in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (1.82)	18.2507
2000's	19 (17.27)	29.6817
2010's	75 (68.18)	24.3611
2020's	14 (12.73)	2.80

Authors

Authors	Studies
Drewes, AM; Mark, EB; Sieg, M; Vase, L	1
Arnold, S; Bennett, MI; Bromham, N; Chi, Y; Hilgart, JS; Page, AJ; Schmidt-Hansen, M	1
Barrachina, J; Inda, MD; López-Gil, S; López-Gil, V; Margarit, C; Morales, D; Muriel, J; Peiró, AM; Planelles, B; Vara-González, A	1
Ali, S; Carleton, B; Drendel, AL; Gourlay, K; Johnson, DW; Le May, S; Ortiz, S; Rosychuk, RJ; Watts, R; Yukseloglu, A	1
Almeida, W; da Costa, NS; Galiciolli, MEA; Irioda, AC; Lima, LS; Margarete Cestari, M; Nogara, PA; Oliveira, CS; Pereira, ME	1
Berger, M; Hosseinzadeh, A; Krassioukov, A; Maharaj, A; Rizzardo, A; Sachdeva, R	1
Arakawa, S; Chiu, SW; Hiratsuka, Y; Hirayama, H; Inoue, A; Ishiki, H; Kosugi, K; Kubo, E; Matsuda, Y; Miyashita, M; Morita, T; Natsume, M; Nishijima, K; Ouchi, K; Sato, M; Satomi, E; Shigeno, T; Shimizu, M; Shimoda, M; Shimoi, T; Tagami, K; Yamaguchi, T; Yokomichi, N	1
Jimaru, Y; Mitsuba, N; Takahashi, K; Torii, S; Yamada, M	1
Calderini, E; Egan, CG; Iorno, V; Landi, L; Porro, GA	1
Lin, R; Xu, C; Zhao, S	1
Coma, E; González-Barboteo, J; Moreno, D; Olmo, M; Serrano, G	1
Drewes, AM; Frøkjær, JB; Hansen, TM; Mark, EB; Nedergaard, RB	1
Aggarwal, G; Ahmedzai, S; Douglas, C; Green, M; Le, BH; Nicoll, A	1
Amato, F; Ceniti, S; Consoletti, L; Magaldi, D; Mameli, S; Marcassa, C; Notaro, P; Palmieri, V; Pisanu, GM; Vellucci, R	1
Bosse, B; Dupoiron, D; Ellery, A; Hopp, M; Kremers, W; Loewenstein, O; Stachowiak, A	2
Lange, B; Serrie, A; Steup, A	1
Dubois, C; Elling, C; Lange, B; von Zabern, D	1
Ahrens, J; Haeseler, G; Karch, A; Liu, X; Prison, N; Schaefers, D	1
Bai, YJ; Huang, L; Jin, SH; Li, XJ; Liu, DH; Lv, SP; Ma, H; Wang, F; Wang, Y; Zhang, Y; Zhou, JG	1
Huygen, F; Koopmans-Klein, G; Mancini, I; Prenen, H; van Megen, Y; Van Op den Bosch, J	1
Arnold, S; Bennett, MI; Bromham, N; Hilgart, JS; Schmidt-Hansen, M	1
Stubhaug, A	1
Leppert, W; Nosek, H; Nosek, K; Onichimowski, D; Wordliczek, J	1
Coffin, BC; Dickerson, SL; Leppert, W; Morlion, BJ; Mueller-Lissner, SA; O'Brien, T; Vellucci, R	1
Brock, C; Drewes, AM; Gregersen, H; Grønlund, D; Krogh, K; Liao, D; Poulsen, JL	1
Kim, ES	1
Brock, C; Drewes, AM; Gregersen, H; Grønlund, D; Krogh, K; Liao, D; Olesen, AE; Poulsen, JL	1
Ahn, JS; Cho, KJ; Chung, SS; Hwang, CJ; Kim, DS; Kim, JH; Lee, JH; Lee, KY; Moon, SH; Park, HJ; Park, YS	1
Candy, B; Jones, L; Larkin, PJ; Stone, P; Vickerstaff, V	1
Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA	1
Elling, C; Lange, B; Sohns, M; Tempero, J	1
Bødker, MB; Drewes, AM; Frøkjaer, JB; Grønlund, D; Mark, EB; Østergaard, LR	1
Leppert, W; Wordliczek, J; Zajaczkowska, R	1
Beeker, A; Berkhof, J; Neefjes, ECW; Rhodius, CA; Ten Oever, D; van den Berg, HP; van der Vliet, HJ; van der Vorst, MJDL; van der Wijngaart, H; Verheul, HMW	1
Law, PY; Loh, HH; Tao, PL; Wang, Y; Yang, PP; Yeh, TK	1
Ishikawa, H; Sato, J; Shino, M; Suzuki, T; Tanaka, R	1
Falke, D; Gálvez, R; Hans, G; Schäfer, M; Steigerwald, I	1
Hammond, G; Kavanagh, S; Kwong, WJ; Okamoto, A; Upmalis, D; Yang, M	1
Leppert, W	2
Müller-Lissner, S	1
Connola, M; Cuomo, A; Esposito, G; Forte, CA; Marcassa, C; Russo, G	1
Burness, CB; Keating, GM	1
Kuo, A; Meutermans, W; Smith, MT; Wyse, BD	1
Huygen, FJ; Koopmans-Klein, G; van Dongen, VC; van Megen, YJ; Van Zundert, J; Vanelderen, PJ	1
Ahmedzai, SH; Duerr, H; Hopp, M; Janecki, M; Leppert, W; Lomax, M; Pakosz, A	1
De Andrés, J; Koopmans, G; Lux, EA; Simpson, K; Van Megen, Y; Wagemans, M	1
Blagden, M; Bosse, B; Duerr, H; Hafer, J; Hopp, M	1
Clemens, KE; Dunlop, W; Morlion, B	1
Guerriero, F; Marcassa, C; Ricevuti, G; Rollone, M; Sgarlata, C	1
Dickerson, S; Junor, R; Kumar Bhutani, M; Thakur, D	1
Hermanns, K; Hesselbarth, S; Oepen, P	1
O'Brien, T	1
Dioh, A; Gorissen, M; Koopmans-Klein, G; Logé, D; Louis, F; Poelaert, J; van Megen, YJ; Van Op den Bosch, J	1
Mueller-Schwefe, GH; Ueberall, MA	1
Ando, Y; Gyawali, B; Hayashi, N; Honda, K; Shimokata, T; Tsukuura, H	1
Fanelli, A; Fanelli, G	1
Goeree, J; Goeree, R	1
Caldarulo, C; Corli, O; Finocchi, S; Greco, MT; Lazzari, M; Marcassa, C	1
Bindslev, N; Brock, C; Drewes, AM; Hansen, MB; Louring Christrup, L; Nilsson, M; Poulsen, JL	1
Huygen, FJ; Koopmans-Klein, G; Van Megen, YJ; Wagemans, MF; Wartenberg, HC	1
Brock, C; Drewes, AM; Frøkjær, JB; Gram, M; Krogh, K; Nilsson, M; Poulsen, JL; Sandberg, TH	1
Caldarulo, C; Carpenedo, R; Dauri, M; Lazzari, M; Marcassa, C; Natoli, S; Silvi, MB	1
Derry, S; Gaskell, H; Moore, RA; Stannard, C	1
Boese, CK; Bredow, J; Dargel, J; Eysel, P; Lemken, J; Oppermann, J; Spies, CK; Unglaub, F; Zöllner, J	1
Kokki, H; Kokki, M; Kuronen, M; Naaranlahti, T; Nyyssönen, T; Pikkarainen, I; Savolainen, S	1
Fleischer, W; Hopp, M; Leyendecker, P; Nadstawek, J; Reimer, K; Ruckes, C; Wirz, S	1
Fleischer, W; Grothe, B; Hermanns, K; Hopp, M; Leyendecker, P; Meissner, W; Reimer, K; Ruckes, C; Szombati, I; Vondrackova, D; Weber, S	1
Fleischer, W; Hopp, M; Leyendecker, P; Meissner, W; Mueller-Lissner, S; Nadstawek, J; Reimer, K; Ruckes, C; Wirz, S	1
Bosse, B; Buschmann-Kramm, C; Holzer, P; Hopp, M; Leyendecker, P; Maier, C; Mikus, G; Reimer, K; Smith, K; Zenz, M	1
Bosse, B; De Andrés, J; Hopp, M; Krain, B; Kremers, W; Leyendecker, P; Löwenstein, O; Müller-Lissner, S; Nichols, T; Reimer, K; Simpson, K; Troy Ferrarons, J	1
Bond, S; Hopp, M; Krain, B; Kremers, W; Leyendecker, P; Löwenstein, O; Nichols, T; Reimer, K; Rogers, PD; Schutter, U; Uhl, R	1
Hartrick, C; Oh, C; Stegmann, JU; Upmalis, D; Van Hove, I	1
Leyendecker, P; Müller-Lissner, S; Rentz, AM; Yu, R	1
Clemens, KE; Mikus, G	1
Diels, J; Kavanagh, S; Kwong, WJ	1
Kapoor, S	1
Dürr, H; Hakl, M; Hopp, M; Hrib, R; Lejcko, J; Leyendecker, P; Meissner, W; Reimer, K; Sandner-Kiesling, A; Sevcik, P; Tarau, L; Uhl, R	1
Mueller-Lissner, S	1
Blagden, M; Bosse, B; Hopp, M; Leyendecker, P; Löwenstein, O; Lux, EA; Reimer, K; Simpson, KH	1
Clemens, KE; Klaschik, E; Quednau, I	1
Etropolski, M; Kelly, K; Okamoto, A; Rauschkolb, C	1
Cepeda, MS; Kim, M; Sutton, A; Weinstein, R	1
Adile, C; Ferrera, P; Mercadante, S	1
Bosse, B; Buschmann-Kramm, C; Müller-Lissner, S; Ueberall, MA	1
Fehlmann, P	1
Ahmedzai, SH; Bar-Sela, G; Bosse, B; Hopp, M; Leyendecker, P; Nauck, F	1
Habu-Tomita, N; Hamaguchi, K; Hasegawa, M; Hashimoto, H; Inoue, Y; Ito, H; Iwamoto, Y; Kato, A; Kihara, T; Koike, K; Koyabu, K; Minami, K; Nakamura, A; Nanba, K; Narita, M; Nishino, I; Noshi, E; Okabayashi, Y; Suzuki, T	1
Araki, H; Ikesue, H; Ishihara, M; Itoh, Y; Kitaichi, K; Matsunaga, H; Oishi, R; Sendo, T; Suemaru, K; Suetsugu, K	1
Hermanns, K; Junker, U; Nolte, T	1
Barton, G; Dunlop, W; Khan, I; Taylor, A; Uhl, R	1
Huhtala, J; Karjalainen, P; Kokki, H; Kokki, M; Kuusniemi, K; Lemken, J; Oppermann, J; Sjövall, S; Zöllner, J	1
Casali, M; Gafforio, P; Gatti, A; Lazzari, M; Marcassa, C; Sabato, AF; Silvestri, C; Tufaro, G	1
Bjerkelund, CE; Comelon, M; Draegni, T; Lenz, H; Qvigstad, E; Raeder, J; Undersrud, H; Wisloeff-Aase, K	1
Markowitz, J; Schein, J; Staats, PS	1
Dvergsten, C; Gimbel, J; Hale, ME	1
Hori, N; Konishi, T	1
Narita, M; Niikura, K; Ozaki, M; Suzuki, T; Yajima, Y	1
Lin, H; Ling, JY; Luo, WB; Sun, XF; Xia, Y; Zhen, ZJ; Zheng, L	1
Chida, M; Hosokawa, T; Kamoto, T; Miura, T; Narabayashi, M; Nishimura, K; Onozawa, Y; Saijo, Y; Shimoyama, N; Takenoshita, S; Tani, K; Tsushima, T	1
Dean, GE	1
Culpepper-Morgan, JA; Foley, K; Houde, RW; Inturrisi, CE; Kreek, MJ; Marsh, F; Portenoy, RK	1

Reviews

23 review(s) available for oxycodone and Colonic Inertia

Article	Year
Oxycodone for cancer-related pain. The Cochrane database of systematic reviews, 2022, 06-09, Volume: 6 Topics: Adult; Analgesics, Opioid; Cancer Pain; Constipation; Humans; Morphine; Nausea; Neoplasms; Oxycodone; Pain; Quality of Life; Reproducibility of Results; Sleepiness; Vomiting	2022
Oxycodone/naloxone prolonged-release tablets in patients with moderate-to-severe, chronic cancer pain: Challenges in the context of hepatic impairment. Asia-Pacific journal of clinical oncology, 2022, Volume: 18, Issue:1 Topics: Analgesics, Opioid; Cancer Pain; Constipation; Delayed-Action Preparations; Humans; Liver Diseases; Naloxone; Neoplasms; Oxycodone; Tablets	2022
Efficacy and safety of tapentadol prolonged release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled release-controlled studies. Current medical research and opinion, 2017, Volume: 33, Issue:8 Topics: Aged; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Female; Health Status; Humans; Male; Middle Aged; Nausea; Osteoarthritis, Knee; Oxycodone; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Vomiting	2017
Opioid-Induced Constipation Relief From Fixed-Ratio Combination Prolonged-Release Oxycodone/Naloxone Compared With Oxycodone and Morphine for Chronic Nonmalignant Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of pain and symptom management, 2017, Volume: 54, Issue:5 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Humans; Morphine; Naloxone; Oxycodone; Randomized Controlled Trials as Topic	2017
Oxycodone for cancer-related pain. The Cochrane database of systematic reviews, 2017, 08-22, Volume: 8 Topics: Aged; Analgesics, Opioid; Cancer Pain; Constipation; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Nausea; Neoplasms; Oxycodone; Pain Measurement; Quality of Life; Randomized Controlled Trials as Topic; Sleep Stages; Vomiting	2017
Oral Prolonged-Release Oxycodone/Naloxone for Managing Pain and Opioid-Induced Constipation: A Review of the Evidence. Pain practice : the official journal of World Institute of Pain, 2018, Volume: 18, Issue:5 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Naloxone; Narcotic Antagonists; Oxycodone; Pain Management	2018
Oxycodone/Naloxone Prolonged Release: A Review in Severe Chronic Pain. Clinical drug investigation, 2017, Volume: 37, Issue:12 Topics: Adult; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Diarrhea; Drug Combinations; Gastrointestinal Tract; Humans; Naloxone; Nausea; Neoplasms; Oxycodone	2017
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. The Cochrane database of systematic reviews, 2018, 06-05, Volume: 6 Topics: Constipation; Defecation; Female; Gastrointestinal Agents; Humans; Intestinal Diseases; Male; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Related Disorders; Oxycodone; Palliative Care; Piperidines; Quaternary Ammonium Compounds; Randomized Controlled Trials as Topic; Receptors, Opioid, mu	2018
Efficacy and safety of tapentadol prolonged release formulation in the treatment of elderly patients with moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo-, and active-controlled trials. Current medical research and opinion, 2018, Volume: 34, Issue:12 Topics: Aged; Chronic Pain; Clinical Trials, Phase III as Topic; Constipation; Delayed-Action Preparations; Double-Blind Method; Female; Health Status Indicators; Humans; Male; Middle Aged; Nausea; Osteoarthritis, Knee; Oxycodone; Randomized Controlled Trials as Topic; Tapentadol; Vertigo; Vomiting	2018
The role of oxycodone/naloxone in the management of patients with pain and opioid-induced constipation. Expert opinion on pharmacotherapy, 2019, Volume: 20, Issue:5 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Gastrointestinal Diseases; Humans; Laxatives; Naloxone; Narcotic Antagonists; Oxycodone; Receptors, Opioid; Receptors, Opioid, mu; Tablets	2019
Oxycodone/naloxone in the management of patients with pain and opioid-induced bowel dysfunction. Current drug targets, 2014, Volume: 15, Issue:1 Topics: Constipation; Drug Combinations; Gastrointestinal Tract; Humans; Naloxone; Oxycodone; Pain	2014
[Opiate induced constipation--mechanisms, relevance and treatment]. Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:43 Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Constipation; Drug Therapy, Combination; Gastrointestinal Motility; Humans; Laxatives; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds	2013
Oxycodone/Naloxone prolonged-release: a review of its use in the management of chronic pain while counteracting opioid-induced constipation. Drugs, 2014, Volume: 74, Issue:3 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Drug Interactions; Humans; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Quality of Life	2014
Quality of life and healthcare resource in patients receiving opioids for chronic pain: a review of the place of oxycodone/naloxone. Clinical drug investigation, 2015, Volume: 35, Issue:1 Topics: Analgesics, Opioid; Animals; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Gastrointestinal Diseases; Health Resources; Humans; Naloxone; Narcotic Antagonists; Oxycodone; Quality of Life; Randomized Controlled Trials as Topic	2015
Impact of prolonged-release oxycodone/naloxone on outcomes affecting patients' daily functioning in comparison with extended-release tapentadol: a systematic review. Clinical therapeutics, 2015, Jan-01, Volume: 37, Issue:1 Topics: Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Headache; Humans; Naloxone; Nausea; Oxycodone; Phenols; Quality of Life; Tapentadol; Vomiting	2015
Opioid-induced constipation. Scandinavian journal of gastroenterology, 2015, Volume: 50, Issue:11 Topics: Chloride Channel Agonists; Chronic Pain; Constipation; Humans; Laxatives; Lubiprostone; Naloxone; Oxycodone; Peptides; Phenols; Receptors, Opioid, mu; Tapentadol	2015
Developments in managing severe chronic pain: role of oxycodone-naloxone extended release. Drug design, development and therapy, 2015, Volume: 9 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Naloxone; Narcotic Antagonists; Oxycodone; Quality of Life; Severity of Illness Index	2015
Oxycodone for neuropathic pain in adults. The Cochrane database of systematic reviews, 2016, Jul-28, Volume: 7 Topics: Adult; Aged; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Diabetic Neuropathies; Disorders of Excessive Somnolence; Dizziness; Female; Humans; Male; Middle Aged; Nausea; Neuralgia, Postherpetic; Oxycodone; Randomized Controlled Trials as Topic	2016
Meeting the challenges of opioid-induced constipation in chronic pain management - a novel approach. Pharmacology, 2009, Volume: 83, Issue:1 Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Constipation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Laxatives; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quality of Life	2009
Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction: review of efficacy and safety data in the treatment of patients experiencing chronic pain. Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:2 Topics: Administration, Oral; Chronic Disease; Clinical Trials as Topic; Constipation; Drug Administration Schedule; Drug Therapy, Combination; Humans; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Quality of Life; Receptors, Opioid; Safety	2010
Fixed combination of oxycodone with naloxone: a new way to prevent and treat opioid-induced constipation. Advances in therapy, 2010, Volume: 27, Issue:9 Topics: Analgesics, Opioid; Constipation; Drug Combinations; Humans; Laxatives; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Treatment Outcome	2010
The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review. Advances in therapy, 2010, Volume: 27, Issue:10 Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Laxatives; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds	2010
[Basic studies on cancer pain control]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10 Topics: Analgesics, Opioid; Animals; Constipation; Dose-Response Relationship, Drug; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Vomiting; World Health Organization	2005

Trials

42 trial(s) available for oxycodone and Colonic Inertia

Article	Year
Importance of blinding and expectations in opioid-induced constipation: evidence from a randomized controlled trial. Scandinavian journal of pain, 2022, 04-26, Volume: 22, Issue:2 Topics: Analgesics, Opioid; Constipation; Humans; Male; Motivation; Opioid-Induced Constipation; Oxycodone	2022
Long-term effect of oxycodone/naloxone on the management of postoperative pain after hysterectomy: a randomized prospective study. Minerva anestesiologica, 2020, Volume: 86, Issue:5 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hysterectomy; Naloxone; Oxycodone; Pain, Postoperative; Prospective Studies	2020
Controlled Release of Oxycodone as an Opioid Titration for Cancer Pain Relief: A Retrospective Study. Medical science monitor : international medical journal of experimental and clinical research, 2020, Mar-18, Volume: 26 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nausea; Oxycodone; Pain Management; Pain Measurement; Retrospective Studies; Sleepiness; Treatment Outcome; Vomiting; Xerostomia; Young Adult	2020
Although tapentadol and oxycodone both increase colonic volume, tapentadol treatment resulted in softer stools and less constipation: a mechanistic study in healthy volunteers. Scandinavian journal of pain, 2021, 04-27, Volume: 21, Issue:2 Topics: Colon; Constipation; Cross-Over Studies; Healthy Volunteers; Humans; Male; Oxycodone; Tapentadol	2021
High dosage of a fixed combination oxycodone/naloxone prolonged release: efficacy and tolerability in patients with chronic cancer pain. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Analgesics; Breakthrough Pain; Cancer Pain; Chronic Pain; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Laxatives; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Pain Management; Pain Measurement; Quality of Life	2017
Long-term efficacy and safety of oxycodone-naloxone prolonged-release formulation (up to 180/90 mg daily) - results of the open-label extension phase of a phase III multicenter, multiple-dose, randomized, controlled study. European journal of pain (London, England), 2017, Volume: 21, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Oxycodone; Pain; Pain Management; Pain Measurement; Quality of Life; Treatment Outcome; Young Adult	2017
Tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a double-blind, randomized, placebo- and oxycodone controlled release-controlled study. Current medical research and opinion, 2017, Volume: 33, Issue:8 Topics: Aged; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Female; Health Status; Humans; Male; Middle Aged; Nausea; Osteoarthritis, Knee; Oxycodone; Phenols; Tapentadol; Vomiting	2017
A phase III randomized controlled study on the efficacy and improved bowel function of prolonged-release (PR) oxycodone-naloxone (up to 160/80 mg daily) vs oxycodone PR. European journal of pain (London, England), 2017, Volume: 21, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Oxycodone; Pain Management; Treatment Outcome; Young Adult	2017
Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone. BMC anesthesiology, 2017, 07-11, Volume: 17, Issue:1 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Naloxone; Orthopedic Procedures; Oxycodone; Pain Measurement; Pain, Postoperative; Phenols; Postoperative Nausea and Vomiting; Prospective Studies; Single-Blind Method; Tapentadol	2017
Prolonged release oxycodone and naloxone treatment counteracts opioid-induced constipation in patients with severe pain compared to previous analgesic treatment. Current medical research and opinion, 2017, Volume: 33, Issue:12 Topics: Aged; Analgesics, Opioid; Chronic Pain; Constipation; Defecation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Laxatives; Male; Middle Aged; Naloxone; Oxycodone; Prospective Studies; Quality of Life	2017
A comparison of oral controlled-release morphine and oxycodone with transdermal formulations of buprenorphine and fentanyl in the treatment of severe pain in cancer patients. Drug design, development and therapy, 2017, Volume: 11 Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Cancer Pain; Constipation; Delayed-Action Preparations; Drug Therapy, Combination; Fentanyl; Humans; Lactulose; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Severity of Illness Index	2017
Prolonged-Release Oxycodone/Naloxone Improves Anal Sphincter Relaxation Compared to Oxycodone Plus Macrogol 3350. Digestive diseases and sciences, 2017, Volume: 62, Issue:11 Topics: Adolescent; Adult; Anal Canal; Analgesics, Opioid; Constipation; Cross-Over Studies; Defecation; Delayed-Action Preparations; Denmark; Double-Blind Method; Drug Combinations; Healthy Volunteers; Humans; Male; Muscle Relaxation; Naloxone; Narcotic Antagonists; Oxycodone; Polyethylene Glycols; Pressure; Surveys and Questionnaires; Time Factors; Young Adult	2017
The impact of naloxegol on anal sphincter function - Using a human experimental model of opioid-induced bowel dysfunction. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, May-30, Volume: 117 Topics: Administration, Oral; Adult; Anal Canal; Analgesics, Opioid; Constipation; Cross-Over Studies; Defecation; Denmark; Double-Blind Method; Humans; Male; Middle Aged; Morphinans; Narcotic Antagonists; Oxycodone; Polyethylene Glycols; Pressure; Time Factors; Treatment Outcome; Young Adult	2018
Analgesic Efficacy and Safety of Prolonged-Release Oxycodone/Naloxone in Korean Patients with Chronic Pain from Spinal Disorders. Clinics in orthopedic surgery, 2018, Volume: 10, Issue:1 Topics: Aged; Analgesics, Opioid; Back Pain; Chronic Pain; Constipation; Delayed-Action Preparations; Dizziness; Drug Combinations; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Naloxone; Nausea; Oxycodone; Pain Measurement; Quality of Life; Republic of Korea; Severity of Illness Index; Spinal Diseases	2018
MRI analysis of fecal volume and dryness: Validation study using an experimental oxycodone-induced constipation model. Journal of magnetic resonance imaging : JMRI, 2019, Volume: 50, Issue:3 Topics: Adult; Analgesics, Opioid; Colon; Constipation; Cross-Over Studies; Double-Blind Method; Feces; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oxycodone; Prospective Studies; Reproducibility of Results; Young Adult	2019
Tapentadol prolonged release versus strong opioids for severe, chronic low back pain: results of an open-label, phase 3b study. Advances in therapy, 2013, Volume: 30, Issue:3 Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Chronic Pain; Constipation; Delayed-Action Preparations; Female; Fentanyl; Humans; Hydromorphone; Low Back Pain; Male; Middle Aged; Morphine; Neuralgia; Oxycodone; Pain Measurement; Phenols; Severity of Illness Index; Tapentadol	2013
Bowel function after tapentadol and oxycodone immediate release (IR) treatment in patients with low back or osteoarthritis pain. The Clinical journal of pain, 2013, Volume: 29, Issue:8 Topics: Adolescent; Adult; Analgesics, Opioid; Constipation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Gastroenteritis; Humans; Laxatives; Low Back Pain; Male; Osteoarthritis; Oxycodone; Pain; Phenols; Surveys and Questionnaires; Tapentadol; Time Factors; Young Adult	2013
Patient preference with respect to QoL and reduction in opioid-induced constipation (OIC) after treatment with prolonged-release (PR) oxycodone/naloxone compared with previous analgesic therapy [PREFER study]. International journal of clinical practice, 2014, Volume: 68, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Oxycodone; Patient Preference; Quality of Life	2014
Long-term safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate-to-severe chronic cancer pain. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:3 Topics: Aged; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Pain Management; Pain Measurement; Quality of Life; Severity of Illness Index; Tablets; Treatment Outcome	2015
Fixed ratio (2:1) prolonged-release oxycodone/naloxone combination improves bowel function in patients with moderate-to-severe pain and opioid-induced constipation refractory to at least two classes of laxatives. Current medical research and opinion, 2014, Volume: 30, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Defecation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Laxatives; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Treatment Outcome	2014
Long-term evaluation of combined prolonged-release oxycodone and naloxone in patients with moderate-to-severe chronic pain: pooled analysis of extension phases of two Phase III trials. Neurogastroenterology and motility, 2014, Volume: 26, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Analgesics; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Oxycodone; Surveys and Questionnaires	2014
Safety and efficacy of oxycodone/naloxone vs. oxycodone vs. morphine for the treatment of chronic low back pain: results of a 12 week prospective, randomized, open-label blinded endpoint streamlined study with prolonged-release preparations. Current medical research and opinion, 2015, Volume: 31, Issue:7 Topics: Adult; Aged; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Germany; Humans; Low Back Pain; Male; Middle Aged; Morphine; Naloxone; Oxycodone; Prospective Studies; Young Adult	2015
Short-term oxycodone treatment does not affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon. Scandinavian journal of gastroenterology, 2016, Volume: 51, Issue:5 Topics: Adult; Analgesics, Opioid; Biopsy; Colon, Sigmoid; Constipation; Cross-Over Studies; Dose-Response Relationship, Drug; Follow-Up Studies; Gastrointestinal Motility; Healthy Volunteers; Humans; Intestinal Mucosa; Ion Transport; Male; Middle Aged; Oxycodone; Rectum; Time Factors; Young Adult	2016
Opioid-induced bowel dysfunction in healthy volunteers assessed with questionnaires and MRI. European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:5 Topics: Adult; Analgesics, Opioid; Constipation; Cross-Over Studies; Defecation; Denmark; Double-Blind Method; Gastrointestinal Motility; Healthy Volunteers; Humans; Intestines; Magnetic Resonance Imaging; Male; Middle Aged; Oxycodone; Pain Measurement; Pain Perception; Pain Threshold; Predictive Value of Tests; Surveys and Questionnaires; Time Factors; Young Adult	2016
Effect of prolonged-released oxycodone/naloxone in postoperative pain management after total knee replacement: a nonrandomized prospective trial. Journal of clinical anesthesia, 2016, Volume: 33 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Constipation; Delayed-Action Preparations; Female; Humans; Intestines; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities; Postoperative Complications; Prospective Studies	2016
Opioid-Induced Bowel Dysfunction in Patients Undergoing Spine Surgery: Comparison of Oxycodone and Oxycodone-Naloxone Treatment. Advances in therapy, 2017, Volume: 34, Issue:1 Topics: Adult; Aged; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Neurosurgical Procedures; Outcome Assessment, Health Care; Oxycodone; Pain, Postoperative; Prospective Studies; Single-Blind Method; Surveys and Questionnaires	2017
Patient assessment of a novel therapeutic approach for the treatment of severe, chronic pain. International journal of clinical practice, 2008, Volume: 62, Issue:8 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Chronic Disease; Constipation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Patient Satisfaction; Prospective Studies; Severity of Illness Index; Treatment Outcome	2008
Analgesic efficacy and safety of oxycodone in combination with naloxone as prolonged release tablets in patients with moderate to severe chronic pain. The journal of pain, 2008, Volume: 9, Issue:12 Topics: Analgesics, Opioid; Chronic Disease; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Low Back Pain; Male; Naloxone; Narcotic Antagonists; Oxycodone; Pain Measurement; Severity of Illness Index; Time Factors; Treatment Outcome	2008
A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation. European journal of pain (London, England), 2009, Volume: 13, Issue:1 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement	2009
Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain. Current medical research and opinion, 2008, Volume: 24, Issue:12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Europe; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Outpatients; Oxycodone; Pain; Primary Health Care	2008
Combined prolonged-release oxycodone and naloxone improves bowel function in patients receiving opioids for moderate-to-severe non-malignant chronic pain: a randomised controlled trial. Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:4 Topics: Analgesics, Opioid; Chronic Disease; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Treatment Outcome	2009
Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: a 10-day, phase III, randomized, double-blind, active- and placebo-controlled Clinical therapeutics, 2009, Volume: 31, Issue:2 Topics: Adult; Aged; Analgesics, Opioid; Constipation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Osteoarthritis, Hip; Osteoarthritis, Knee; Oxycodone; Pain; Phenols; Tapentadol; Vomiting; Young Adult	2009
Validation of the Bowel Function Index to detect clinically meaningful changes in opioid-induced constipation. Journal of medical economics, 2009, Volume: 12, Issue:4 Topics: Analgesics, Opioid; Chronic Disease; Constipation; Delayed-Action Preparations; Diagnostic Self Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Reproducibility of Results; Severity of Illness Index; Surveys and Questionnaires	2009
Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain. International journal of clinical practice, 2010, Volume: 64, Issue:6 Topics: Aged; Analgesics, Opioid; Chronic Disease; Constipation; Defecation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Treatment Outcome	2010
Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials. BMC clinical pharmacology, 2010, Sep-29, Volume: 10 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Patient Discharge; Safety; Treatment Outcome; Young Adult	2010
Bowel function during pain therapy with oxycodone/naloxone prolonged-release tablets in patients with advanced cancer. International journal of clinical practice, 2011, Volume: 65, Issue:4 Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Tablets	2011
Comparable efficacy and superior gastrointestinal tolerability (nausea, vomiting, constipation) of tapentadol compared with oxycodone hydrochloride. Advances in therapy, 2011, Volume: 28, Issue:5 Topics: Aged; Analgesics, Opioid; Chronic Disease; Constipation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Joint Diseases; Male; Middle Aged; Nausea; Oxycodone; Pain; Phenols; Tapentadol; Vomiting	2011
A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate/severe, chronic cancer pain. Palliative medicine, 2012, Volume: 26, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Quality of Life	2012
Prolonged-release oxycodone/naloxone in postoperative pain management: from a randomized clinical trial to usual clinical practice. The Journal of international medical research, 2012, Volume: 40, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Oxycodone; Pain Management; Pain, Postoperative; Spine; Treatment Outcome; Young Adult	2012
A comparison of oxycodone prolonged-release vs. oxycodone + naloxone prolonged-release after laparoscopic hysterectomy. Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:4 Topics: Adult; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Laparoscopy; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain, Postoperative; Prospective Studies	2013
Efficacy and safety of oxymorphone extended release in chronic low back pain: results of a randomized, double-blind, placebo- and active-controlled phase III study. The journal of pain, 2005, Volume: 6, Issue:1 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Chronic Disease; Constipation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Low Back Pain; Male; Middle Aged; Oxycodone; Oxymorphone; Pain Measurement; Placebo Effect; Placebos; Sleep Stages; Treatment Outcome	2005
Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: an open-label trial. Japanese journal of clinical oncology, 2008, Volume: 38, Issue:4 Topics: Administration, Oral; Aged; Analgesics, Opioid; Constipation; Drug Administration Schedule; Female; Humans; Linear Models; Male; Middle Aged; Morphinans; Morphine; Morphine Derivatives; Nausea; Neoplasms; Oxycodone; Pain; Prospective Studies; Renal Insufficiency, Chronic; Sleep Stages; Treatment Outcome; Vomiting	2008

Other Studies

45 other study(ies) available for oxycodone and Colonic Inertia

Article	Year
Oxycodone/naloxone versus tapentadol in real-world chronic non-cancer pain management: an observational and pharmacogenetic study. Scientific reports, 2022, 06-16, Volume: 12, Issue:1 Topics: Analgesics, Opioid; Cancer Pain; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Morphine; Naloxone; Oxycodone; Pharmacogenomic Testing; Quality of Life; Tapentadol	2022
Quantifying the intensity of adverse events with ibuprofen and oxycodone: an observational cohort study. BMJ paediatrics open, 2022, Volume: 6, Issue:1 Topics: Analgesics, Opioid; Child; Cohort Studies; Constipation; Double-Blind Method; Fractures, Bone; Humans; Ibuprofen; Oxycodone; Pain; Pain Measurement	2022
Assessment of Neurotoxic Effects of Oxycodone and Naloxone in SH-SY5Y Cell Line. International journal of molecular sciences, 2023, Jan-11, Volume: 24, Issue:2 Topics: Acetylcholinesterase; Analgesics, Opioid; Cell Line; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Molecular Docking Simulation; Naloxone; Neuroblastoma; Oxycodone; Pain, Postoperative; Superoxide Dismutase	2023
No pain, no strain: Targin® mitigates pain and constipation following spinal cord injury. Annals of clinical and translational neurology, 2023, Volume: 10, Issue:3 Topics: Analgesics, Opioid; Autonomic Dysreflexia; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Spinal Cord Injuries	2023
Prevalence of opioid-induced adverse events across opioids commonly used for analgesic treatment in Japan: a multicenter prospective longitudinal study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023, Oct-16, Volume: 31, Issue:12 Topics: Analgesics, Opioid; Cancer Pain; Constipation; Delirium; Fentanyl; Humans; Hydromorphone; Japan; Longitudinal Studies; Nausea; Oxycodone; Prevalence; Prospective Studies; Tramadol; Vomiting	2023
A Retrospective Observational Study of Factors Affecting the Efficacy of Concurrent Prescription of Naldemedine for Opioid-Induced Constipation Caused by Oxycodone Tablets. Biological & pharmaceutical bulletin, 2023, Volume: 46, Issue:12 Topics: Analgesics, Opioid; Body Weight; Constipation; Humans; Laxatives; Narcotic Antagonists; Opioid-Induced Constipation; Oxycodone; Retrospective Studies	2023
Acute opioid withdrawal syndrome from naloxone/naloxegol interaction. BMJ supportive & palliative care, 2021, Volume: 11, Issue:4 Topics: Analgesics, Opioid; Constipation; Humans; Male; Morphinans; Naloxone; Narcotic Antagonists; Oxycodone; Polyethylene Glycols; Substance Withdrawal Syndrome	2021
Advances in understanding and treatment of opioid-induced-bowel-dysfunction, opioid-induced-constipation in particular: Nordic recommendations based on multi-specialist input. Scandinavian journal of pain, 2016, Volume: 11 Topics: Analgesics, Opioid; Constipation; Gastrointestinal Motility; Humans; Intestinal Diseases; Narcotic Antagonists; Oxycodone; Quality of Life; Quaternary Ammonium Compounds; Treatment Outcome	2016
Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report. A&A practice, 2019, Jan-15, Volume: 12, Issue:2 Topics: Analgesics, Opioid; Colonic Pseudo-Obstruction; Constipation; Decompression, Surgical; Humans; Hydromorphone; Intestinal Perforation; Low Back Pain; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Postoperative Complications; Quaternary Ammonium Compounds; Spinal Stenosis	2019
Optimal treatment of opioid induced constipation in daily clinical practice - an observational study. BMC palliative care, 2019, Mar-29, Volume: 18, Issue:1 Topics: Aged; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Laxatives; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neoplasms; Oxycodone; Pain Management; Prospective Studies; Quaternary Ammonium Compounds; Retrospective Studies; Surveys and Questionnaires	2019
Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice. European journal of pharmacology, 2019, Jun-05, Volume: 852 Topics: Analgesics; Animals; Constipation; Drug Tolerance; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Receptors, Opioid, delta; Respiratory Insufficiency	2019
A preliminary study of the effect of naldemedine tosylate on opioid-induced nausea and vomiting. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:3 Topics: Aged; Analgesics, Opioid; Antiemetics; Constipation; Female; Humans; Incidence; Male; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Nausea; Oxycodone; Receptors, Opioid; Retrospective Studies; Vomiting	2020
Efficacy and gastrointestinal tolerability of oral oxycodone/naloxone combination for chronic pain in outpatients with cancer: an observational study. The American journal of hospice & palliative care, 2014, Volume: 31, Issue:8 Topics: Administration, Oral; Ambulatory Care; Analgesics, Opioid; Chronic Pain; Constipation; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Neoplasms; Oxycodone; Pain Management; Pain Measurement; Retrospective Studies; Treatment Outcome	2014
In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile. British journal of pharmacology, 2015, Volume: 172, Issue:2 Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Buprenorphine; Castor Oil; Constipation; Diarrhea; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Hot Temperature; Male; Morphine; Morphine Derivatives; Oxycodone; Pain; Pyrrolidines; Rats, Sprague-Dawley; Respiratory Insufficiency	2015
Efficacy and tolerability of low-dose oral prolonged-release oxycodone/naloxone for chronic nononcological pain in older patients. Clinical interventions in aging, 2015, Volume: 10 Topics: Activities of Daily Living; Aged; Chronic Pain; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Female; Humans; Italy; Male; Naloxone; Oxycodone; Pain Management; Pain Measurement; Prospective Studies; Quality of Life; Treatment Outcome	2015
Prolonged-release oxycodone/naloxone in opioid-naïve patients - subgroup analysis of a prospective observational study. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:4 Topics: Aged; Constipation; Defecation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Narcotics; Neoplasms; Oxycodone; Pain; Pain Management; Prospective Studies; Quality of Life	2015
The attractiveness of opposites: agonists and antagonists. Journal of pain & palliative care pharmacotherapy, 2015, Volume: 29, Issue:1 Topics: Administration, Oral; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Naloxone; Narcotic Antagonists; Oxycodone; Pain	2015
Treatment with prolonged-release oxycodone/naloxone improves pain relief and opioid-induced constipation compared with prolonged-release oxycodone in patients with chronic severe pain and laxative-refractory constipation. Clinical therapeutics, 2015, Apr-01, Volume: 37, Issue:4 Topics: Aged; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Laxatives; Male; Middle Aged; Naloxone; Oxycodone; Quality of Life	2015
Cost-effectiveness analysis of oxycodone with naloxone versus oxycodone alone for the management of moderate-to-severe pain in patients with opioid-induced constipation in Canada. Journal of medical economics, 2016, Volume: 19, Issue:3 Topics: Adult; Analgesics, Opioid; Canada; Chronic Pain; Constipation; Cost-Benefit Analysis; Drug Combinations; Female; Humans; Male; Monte Carlo Method; Naloxone; Narcotic Antagonists; Oxycodone; Pain Management; Quality-Adjusted Life Years; Treatment Outcome	2016
Efficacy and tolerability of oral oxycodone and oxycodone/naloxone combination in opioid-naïve cancer patients: a propensity analysis. Drug design, development and therapy, 2015, Volume: 9 Topics: Aged; Analgesics, Opioid; Chronic Pain; Constipation; Defecation; Drug Combinations; Female; Humans; Laxatives; Male; Middle Aged; Naloxone; Narcotic Antagonists; Neoplasms; Oxycodone; Pain Measurement; Propensity Score; Quality of Life; Retrospective Studies; Rome; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Treatment Outcome	2015
The efficacy of standard laxative use for the prevention and treatment of opioid induced constipation during oxycodone use: a small Dutch observational pilot study. Expert review of gastroenterology & hepatology, 2016, Volume: 10, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Constipation; Defecation; Diarrhea; Female; Humans; Intestines; Laxatives; Male; Middle Aged; Narcotic Antagonists; Netherlands; Oxycodone; Pilot Projects; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome	2016
Switching to low-dose oral prolonged-release oxycodone/naloxone from WHO-Step I drugs in elderly patients with chronic pain at high risk of early opioid discontinuation. Clinical interventions in aging, 2016, Volume: 11 Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Italy; Male; Naloxone; Oxycodone; Pain Measurement; Quality of Life; Retrospective Studies; Severity of Illness Index	2016
Costs of gastrointestinal events after outpatient opioid treatment for non-cancer pain. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:4 Topics: Adult; Aged; Ambulatory Care; Analgesics, Opioid; Cohort Studies; Constipation; Databases, Factual; Drug Prescriptions; Drug Utilization; Emergency Medical Services; Female; Gastrointestinal Diseases; Humans; Hydrocodone; Insurance, Health, Reimbursement; Intestinal Obstruction; Male; Middle Aged; Nausea; Oxycodone; Pain; Retrospective Studies; Socioeconomic Factors; United States; Vomiting	2010
Emerging new therapeutic options for the management of opioid induced constipation. Journal of pain & palliative care pharmacotherapy, 2010, Volume: 24, Issue:1 Topics: Alprostadil; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Laxatives; Lubiprostone; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds	2010
Targinact--opioid pain relief without constipation? Drug and therapeutics bulletin, 2010, Volume: 48, Issue:12 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Follow-Up Studies; Humans; Naloxone; Oxycodone; Pain; Randomized Controlled Trials as Topic	2010
Effect of tapentadol extended release on productivity: results from an analysis combining evidence from multiple sources. The Clinical journal of pain, 2012, Volume: 28, Issue:1 Topics: Adult; Aged; Chronic Pain; Cohort Studies; Constipation; Cross-Sectional Studies; Delayed-Action Preparations; Double-Blind Method; Efficiency; Female; Humans; Male; Markov Chains; Middle Aged; Narcotics; Oxycodone; Phenols; Randomized Controlled Trials as Topic; Retrospective Studies; Surveys and Questionnaires; Tapentadol	2012
High doses of oxycodone-naloxone combination may provide poor analgesia. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:9 Topics: Aged; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Humans; Lung Neoplasms; Male; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Treatment Outcome	2011
The Bowel Function Index for evaluating constipation in pain patients: definition of a reference range for a non-constipated population of pain patients. The Journal of international medical research, 2011, Volume: 39, Issue:1 Topics: Analgesics, Opioid; Chronic Disease; Constipation; Cross-Sectional Studies; Defecation; Female; Germany; Humans; Male; Middle Aged; Naloxone; Oxycodone; Pain; Quality of Life; Reference Values; Research Design; Surveys and Questionnaires	2011
[A year of chronic pain with Targin--experience from daily practice. Interview with Dr. Patricia Fehlmann]. Revue medicale suisse, 2011, Jun-29, Volume: 7, Issue:301 Topics: Administration, Oral; Analgesics, Opioid; Chronic Disease; Constipation; Drug Combinations; Evidence-Based Medicine; Humans; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quality of Life; Switzerland; Treatment Outcome	2011
Distinct relations among plasma concentrations required for different pharmacological effects in oxycodone, morphine, and fentanyl. Journal of pain & palliative care pharmacotherapy, 2011, Volume: 25, Issue:4 Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Constipation; Dose-Response Relationship, Drug; Fentanyl; Male; Models, Animal; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley	2011
A multi-institutional study analyzing effect of prophylactic medication for prevention of opioid-induced gastrointestinal dysfunction. The Clinical journal of pain, 2012, Volume: 28, Issue:5 Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Constipation; Female; Gastrointestinal Diseases; Humans; Japan; Laxatives; Magnesium Oxide; Male; Middle Aged; Morphine; Nausea; Neoplasms; Odds Ratio; Oxycodone; Pain; Vomiting	2012
Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain - results from a large observational study. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:3 Topics: Aged; Analgesics, Opioid; Chronic Pain; Constipation; Defecation; Delayed-Action Preparations; Drug Combinations; Female; Germany; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Neuralgia; Oxycodone; Pain Measurement; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Treatment Outcome	2012
Quality of life benefits and cost impact of prolonged release oxycodone/naloxone versus prolonged release oxycodone in patients with moderate-to-severe non-malignant pain and opioid-induced constipation: a UK cost-utility analysis. Journal of medical economics, 2012, Volume: 15, Issue:3 Topics: Analgesics, Opioid; Cohort Studies; Constipation; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Combinations; Humans; Naloxone; Oxycodone; Pain; Quality of Life; Severity of Illness Index; United Kingdom	2012
Prolonged-release oxycodone/naloxone in nonmalignant pain: single-center study in patients with constipation. Advances in therapy, 2013, Volume: 30, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Male; Middle Aged; Naloxone; Oxycodone; Pain Measurement; Retrospective Studies; Treatment Outcome	2013
Oxycodone + naloxone: choose morphine and optimal laxative therapy instead. Prescrire international, 2013, Volume: 22, Issue:134 Topics: Analgesics, Opioid; Constipation; Drug Combinations; Humans; Laxatives; Morphine; Naloxone; Oxycodone	2013
Incidence of constipation associated with long-acting opioid therapy: a comparative study. Southern medical journal, 2004, Volume: 97, Issue:2 Topics: Aged; Analgesics, Opioid; California; Constipation; Female; Fentanyl; Humans; Incidence; Male; Middle Aged; Morphine; Oxycodone; Pain; Retrospective Studies	2004
[Pain management for cancer patients with critical pathway on computer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2 Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Constipation; Critical Pathways; Humans; Microcomputers; Neoplasms; Oxycodone; Pain Measurement; Pain, Intractable	2005
[Rating of opioids. With rational use for individual treatment goal]. MMW Fortschritte der Medizin, 2006, Aug-31, Volume: 148, Issue:35-36 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Constipation; Humans; Middle Aged; Oxycodone; Pain; Pain Measurement; Prospective Studies; Time Factors; Treatment Outcome	2006
[Quality of life suffers much in constipation. Plea for an intelligent pain therapy]. MMW Fortschritte der Medizin, 2006, Aug-31, Volume: 148, Issue:35-36 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Constipation; Drug Combinations; Humans; Middle Aged; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quality of Life; Surveys and Questionnaires; Time Factors	2006
[A milestone in pain therapy. Intelligent pain therapy with opioid-naloxone combination]. MMW Fortschritte der Medizin, 2007, May-03, Volume: 149, Issue:18 Topics: Chronic Disease; Clinical Trials as Topic; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Naloxone; Narcotics; Oxycodone; Pain	2007
[Feasibility to treat pediatric cancer pain with analgesics for adults and their efficacy]. Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:8 Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Constipation; Delayed-Action Preparations; Feasibility Studies; Female; Fentanyl; Humans; Leukemia; Lymphoma; Male; Morphine; Nausea; Oxycodone; Pain, Intractable; Vomiting; World Health Organization	2007
[New study demonstrates dual effect of an oxycodone/naloxone combination. Strong pain palliation and preserving intestinal function]. MMW Fortschritte der Medizin, 2007, Nov-29, Volume: 149, Issue:48 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Gastrointestinal Motility; Humans; Naloxone; Oxycodone; Pain; Palliative Care; Randomized Controlled Trials as Topic; Sleep	2007
[General practice study reveals simplification of therapy for physician and patients. Patient satisfaction and better quality of life]. MMW Fortschritte der Medizin, 2007, Nov-29, Volume: 149, Issue:48 Topics: Analgesics, Opioid; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Gastrointestinal Motility; Humans; Multicenter Studies as Topic; Naloxone; Oxycodone; Pain; Palliative Care; Patient Satisfaction; Quality of Life; Randomized Controlled Trials as Topic	2007
When analgesia leads to constipation. Nursing, 1995, Volume: 25, Issue:1 Topics: Adult; Constipation; Female; Humans; Oxycodone	1995
Treatment of opioid-induced constipation with oral naloxone: a pilot study. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:1 Topics: Adult; Constipation; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Middle Aged; Naloxone; Oxycodone; Pilot Projects; Substance-Related Disorders	1992