Page last updated: 2024-11-02

oxybutynin and Stroke

oxybutynin has been researched along with Stroke in 9 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"In men with hypogonadism and preexisting or a high risk of cardiovascular disease, testosterone-replacement therapy was noninferior to placebo with respect to the incidence of major adverse cardiac events."3.30Cardiovascular Safety of Testosterone-Replacement Therapy. ( Basaria, S; Bhasin, S; Boden, WE; Chan, A; Cunningham, GR; Davey, D; Dubcenco, E; Flevaris, P; Granger, CB; Huang, B; Kalahasti, V; Khan, N; Khera, M; Li, X; Lincoff, AM; Miller, MG; Mitchell, LM; Nissen, SE; Pencina, KM; Snabes, MC; Thompson, IM; Travison, TG; Wang, Q; Wolski, K; Yi, T, 2023)
"Infections were associated with an increased risk of death (p < 0."2.84Infections Up to 76 Days After Stroke Increase Disability and Death. ( Bath, PM; Bereczki, D; Berge, E; Caso, V; Christensen, H; Collins, R; Czlonkowska, A; El Etribi, A; Farr, TD; Fone, KC; Gommans, J; Laska, AC; Learoyd, AE; Ntaios, G; Ozturk, S; Pocock, SJ; Prasad, K; Shaw, L; Sprigg, N; Trueman, RC; Wardlaw, JM; Woodhouse, L, 2017)
"High blood pressure is a common complication in acute stroke and is associated with a poor outcome."2.76The effect of transdermal glyceryl trinitrate on 24 h ambulatory blood pressure in acute/subacute stroke. ( Bath, AJ; Bath, PM; Geeganage, CM, 2011)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Lincoff, AM1
Bhasin, S1
Flevaris, P1
Mitchell, LM1
Basaria, S1
Boden, WE1
Cunningham, GR1
Granger, CB1
Khera, M1
Thompson, IM1
Wang, Q1
Wolski, K1
Davey, D1
Kalahasti, V1
Khan, N1
Miller, MG1
Snabes, MC1
Chan, A1
Dubcenco, E1
Li, X1
Yi, T1
Huang, B1
Pencina, KM1
Travison, TG1
Nissen, SE1
Appleton, JP2
Krishnan, K1
Bath, PM4
Iwano, T1
Toda, H1
Nakamura, K1
Shimizu, K1
Ejiri, K1
Naito, Y1
Mori, H1
Masuda, T1
Miyoshi, T1
Yoshida, M1
Hikasa, Y1
Morimatsu, H1
Ito, H1
Learoyd, AE1
Woodhouse, L1
Shaw, L1
Sprigg, N2
Bereczki, D1
Berge, E1
Caso, V1
Christensen, H1
Collins, R1
Czlonkowska, A1
El Etribi, A1
Farr, TD1
Gommans, J1
Laska, AC1
Ntaios, G1
Ozturk, S1
Pocock, SJ1
Prasad, K1
Wardlaw, JM1
Fone, KC1
Trueman, RC1
Marchitto, N1
Sindona, F1
Pannozzi, A1
Dalmaso, SG1
Anticoli, S1
Raimondi, G1
Mohammed, K1
Abu Dabrh, AM1
Benkhadra, K1
Al Nofal, A1
Carranza Leon, BG1
Prokop, LJ1
Montori, VM1
Faubion, SS1
Murad, MH1
Brown, S1
Geeganage, CM1
Bath, AJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Collaborative, International, Multicentre, Randomised, Parallel-group, Single and Outcome Blinded, Controlled, Factorial Trial to Investigate the Safety and Efficacy of Treatment With Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, a[NCT00989716]Phase 33,500 participants (Anticipated)Interventional2001-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for oxybutynin and Stroke

ArticleYear
Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke.
    Expert opinion on drug delivery, 2020, Volume: 17, Issue:3

    Topics: Administration, Cutaneous; Hemodynamics; Humans; Nitric Oxide Donors; Nitroglycerin; Quality of Life

2020
Oral vs Transdermal Estrogen Therapy and Vascular Events: A Systematic Review and Meta-Analysis.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:11

    Topics: Administration, Oral; Estrogen Replacement Therapy; Evidence-Based Medicine; Female; Humans; Menopau

2015
Therapeutic Potential of Transdermal Glyceryl Trinitrate in the Management of Acute Stroke.
    CNS drugs, 2017, Volume: 31, Issue:1

    Topics: Administration, Cutaneous; Blood Pressure; Cerebrovascular Circulation; Humans; Nitric Oxide Donors;

2017

Trials

4 trials available for oxybutynin and Stroke

ArticleYear
Cardiovascular Safety of Testosterone-Replacement Therapy.
    The New England journal of medicine, 2023, Jul-13, Volume: 389, Issue:2

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Ge

2023
Preventative effects of bisoprolol transdermal patches on postoperative atrial fibrillation in high-risk patients undergoing non-cardiac surgery: A subanalysis of the MAMACARI study.
    Journal of cardiology, 2021, Volume: 78, Issue:5

    Topics: Aged; Atrial Fibrillation; Bisoprolol; Humans; Postoperative Complications; Risk Factors; Stroke; Tr

2021
Infections Up to 76 Days After Stroke Increase Disability and Death.
    Translational stroke research, 2017, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Incidence; Infections; Male; Middle Aged; Nitroglyce

2017
The effect of transdermal glyceryl trinitrate on 24 h ambulatory blood pressure in acute/subacute stroke.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:4

    Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Male; Nit

2011

Other Studies

2 other studies available for oxybutynin and Stroke

ArticleYear
Safety and efficacy of Rotigotine in hospedalized patients with Vascular Parkinsonism aged 75 and older: effects on movement, praxis capacities, time-space orientation, quality of life and adherence to medical therapy.
    Acta bio-medica : Atenei Parmensis, 2019, 05-23, Volume: 90, Issue:2

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Brain Ischemia; Cognition; Dopamine Agonists; Fe

2019
Transdermal hormone replacement therapy not associated with an increased risk of stroke.
    Menopause international, 2010, Volume: 16, Issue:2

    Topics: Aged; Case-Control Studies; Female; Hormone Replacement Therapy; Humans; Longitudinal Studies; Meta-

2010